Low magnesium if poor kidney, poor gut, cancer, cancer drugs – Jan 2021

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Hypomagnesemia in the Cancer Patient

Kidney360. 2021 Jan 28; 2(1): 154–166.. doi: 10.34067/KID.0005622020
Biruh T. Workeneh, 1 Nupur N. Uppal, 2 Kenar D. Jhaveri, 2 and Helbert Rondon-Berrioscorresponding author 3

Hypomagnesemia is a common medical problem that contributes to the morbidity and mortality of patients with cancer. This review summarizes magnesium physiology and highlights the mechanisms underlying magnesium disturbances due to cancer and cancer treatment. The causes of hypomagnesemia can be categorized according to the pathophysiologic mechanism: decreased intake, transcellular shift, gastrointestinal losses, and kidney losses. Patients with cancer are at risk for opportunistic infections, frequently experience cardiovascular complications, and often receive classes of medications that cause or exacerbate hypomagnesemia. Also, cancer-specific therapies are responsible for hypomagnesemia, including platinum-based chemotherapy, anti-EGF receptor mAbs, human EGF receptor-2 target inhibitors (HER2), and calcineurin inhibitors. Urinary indices, such as the fractional excretion of magnesium, can provide useful information about the etiology. The management of hypomagnesemia depends on the magnitude of hypomagnesemia and the underlying cause. We recommended checking serum magnesium at the beginning of treatment and as part of routine monitoring throughout cancer treatment. Opportunities exist for potential research and practice improvement, including further characterization of hypomagnesemia regarding the clinical effect on cancer outcomes, preventing hypomagnesemia in patients receiving high-risk anticancer agents, and developing effective therapeutic strategies.
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VitaminDWiki - Magnesium and Vitamin D contains

331 items in category, see also

• Overview Magnesium and vitamin D
• Magnesium deficiency – causes and symptoms – May 2016
• Vitamins and Metals needed by the Immune System – Jan 2020
• Magnesium: intake decreased, difficult to measure in body – Sept 2018
• Magnesium deficiency estimated by just 6 Yes No questions - Dec 2019
• Magnesium fights diabetes (yet again)– meta-analysis Nov 20218
• Intracellular Magnesium and Vitamin D - a few studies
• Magnesium in Healthcare (Rickets, Stones, Pregnancy, Depression, etc.) with level of evidence – Sept 2017
• Magnesium is great for health, topical much faster than oral, MgCl2 is the best – 2019
• Magnesium is important for health but levels are low – July 2018
• How to get lots of Magnesium – especially needed for Coimbra MS and Autoimmune Protocol
• COVID death 6.9X less likely if high Magnesium to Calcium ratio – April 2022
• Magnesium etc. reduced in crops (must supplement) – 2009

Mg and Vitamin D

• Intracellular Magnesium and Vitamin D - a few studies
• Vitamin D and Magnesium need each other - many studies
• Why Vitamin D is Useless without This Critical Nutrient (Magnesium) - Jan 2019
• 500 mg of Magnesium for 8 weeks increased Vitamin D by 4 ng – July 2020
• Magnesium and Vitamin D - pre-colon cancer – RCT Dec 2018
• Magnesium is vital to Vitamin D in 4 places (maybe 8) – March 2018
• Magnesium and Vitamin D – recent deficiencies, needed, synergistic - good overview 2017
• Vitamin D Cofactors in a nutshell
• Magnesium and Vitamin D - similar, different and synergistic

Dr. Dean

• Some Podcasts by Dr. C Dean – Magnesium, Vitamin D, Iodine, etc.
• Magnesium and the body - depletion and reduced intake - Dean Oct 2019
• Magnesium, Vitamin D, Omega-3, TSH - importance and testing - Dean and Baggerly - Oct 2019

Number of studies in both of the categories of Magnesium and:

Bone 15,  Cardiovascular 17,   Diabetes 27. Depression 14,  Obesity 11,   Omega-3 31,  Zinc 21,  Pregnancy 10,  Headache 10,   Virus 25,   Calcium 24   Virus 25   Mortality 7   Hypertension 11   Inflammation 3   Pain 7 etc.

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VitaminDWiki Magnesium pages with CANCER in title (11 as of June 2022)

This list is automatically updated