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Loading dose of 60,000 IU Vitamin D once a week for 5 weeks safely raised deficient to above 30 ng – Nov 2024

Most of the world uses Vitamin D loading doses of

  1. 50,000 IU weekly
  2. 50,000 IU daily for a week
  3. 200,000 to 400,000 IU as a single dose in critical situations

India, and a few others, use 60,000 instead of 50,000 IU
Do not recall ever seeing an adverse reaction to any Vitamin D loading doses

Safety and Efficacy of Loading Doses of Vitamin D: Recommendations for Effective Repletion

Pharmaceuticals 2024, 17(12), 1620; https://doi.org/10.3390/ph17121620
by Béla E. Tóth 1,*,István Takács 2,Kristóf Kádár 3,Sara Mirani 1,Miklós Vecsernyés 1ORCID and Péter Lakatos 2
1 Department of Pharmaceutical Surveillance and Economy, Faculty of Pharmacy, University of Debrecen, 4032 Debrecen, Hungary
2 Department of Internal Medicine and Oncology, Semmelweis University, 1085 Budapest, Hungary
3 Department of Oral Biology, Semmelweis University, 1085 Budapest, Hungary
* Author to whom correspondence should be addressed.
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Background/Objectives: Epidemiological data on vitamin D status revealed that, despite various dosage and durations of supplementation, the effectiveness often fails to achieve optimal outcomes. The need for higher doses than previously recommended was suggested, but several modifying factors should be considered, including the level of deficiency, and BMI. The objectives of this post hoc evaluation are to characterize treatment effectiveness based on the applied dose, duration and BMI; and to assess the safety aspects associated with rapid repletion of vitamin D.

Methods: Vitamin D deficient subjects selected in the post-hoc analysis: seventy patients included from a combined loading-maintenance supplementation (300,000 IU followed by 60,000 IU) protocol and 62 deficient subjects who received a low-dose maintenance (1000 IU/day) therapy. The risk of overload and the incidence of hypercalciuria and hypercalcemia resulting from loading or post-loading maintenance were investigated.

Results: The moderate–fast-loading schedule of 60,000 IU per week for 5 weeks, effectively achieves the target in 25(OH)D levels over 30 ng/mL for all deficient subjects, regardless of their BMI. Slower loading with lower weekly doses confirms the safety of supplementation, but the effectiveness is dependent on the subjects’ BMI; overweight and obese patients require higher doses to reach the same vitamin D levels. No difference in safety parameters observed compared to low-dose therapies.

Conclusions: The loading treatment involving a total dose of 300,000 IU administered over 5 or 10 weeks is effective for repletion, does not lead to 25(OH)D overload, and poses no additional risks of hypercalcemia or hypercalciuria. Furthermore, there are no safety concerns regarding changes in bone resorption markers. A combination of the loading treatment with a subsequent maintenance dose of 2000 IU daily is adequate to achieve the target vitamin D levels.
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VitaminDWiki – Loading Dose of Vitamin D category contains

209 items in category
see also Overview Loading of vitamin D   Overview Toxicity of vitamin D
Better than Daily 1: Fewer chances to forget, 2) Gets past receptor barrier
Injection category has 68 items
 
It appears that over 1 million Vitamin D loading doses have been taken
Doses ranged from 100,000 to 600,000 IU over a period of a day to a month
No reports of serious adverse reactions
Many studies report on the benefits resulting from loading doses

TOP articles in Loading Dose of Vitamin D

160 VitaminDWiki pages have 50,000 or 50000 IU in the title

This list is automatically updated

Items found: 161
Title Modified
CIS (MS) reduced 36% by two capsules of 50,000 IU of Vitamin D taken biweekly – RCT March 2025 10 Mar, 2025
Osteoporosis in France can be fought with 50,000 IU of Vitamin D, weekly then bi-weekly (30-60ng) - Feb 2025 21 Feb, 2025
Smoking depression, etc. reduced by Vitamin D (bi-weekly, 50,000 IU) - RCT Dec 2021 19 Jan, 2025
Depression cost-effectively reduced by 50,000 IU of Vitamin D monthly (Iranian teens) – July 2023 28 Nov, 2024
Sleep disorders nicely treated by Vitamin D (50,000 IU twice a month) – RCT May 2017 16 Oct, 2024
Migraine Headache duration and intensity reduced by 50,000 IU vitamin D every two week plus probiotics – RCT Oct 2024 14 Oct, 2024
Health can be greatly improved by weekly 50,000 IU of Vitamin D - video and charts Lahore- March 2023 30 Aug, 2024
Health can be greatly improved by weekly 50,000 IU of Vitamin D - video Lahore - March 2023 30 Aug, 2024
High-Doses (50,000 IU weekly, etc.) if at high risk of Vitamin D deficiency - Aug 2024 12 Aug, 2024
50,000 IU of Vitamin D monthly is safe for 1 year, levels still rising – June 2024 13 Jun, 2024
Depression in seniors greatly reduced by Vitamin D (50,000 IU weekly) – meta-analysis June 2023 10 Jun, 2024
Children with ADHD again helped by 50,000 IU weekly Vitamin D – RCT June 2024 18 May, 2024
Sepsis (with mechanical ventilation) treated by 5days of 50,000 IU of Vitamin D – RCT May 2024 06 May, 2024
50,000 IU of Vitamin D - many studies 07 Apr, 2024
50,000 IU of Vitamin D weekly greatly decreased bone loss from prostate cancer therapy - RCT March 2024 24 Mar, 2024
PMS reduced by 50,000 IU every two weeks - RCT Jan 2024 15 Jan, 2024
Following Bariatric surgery, weekly 50,000 IU of standard Vitamin D is not enough – Jan 2024 12 Jan, 2024
Venous ulcers healed 4X faster with weekly 50,000 IU vitamin D – RCT Oct 2012 08 Sep, 2023
Muscle pain in obese women reduced by aerobic exercise plus 50,000 IU Vitamin D - RCT May 2021 27 Aug, 2023
IBS reduced by 50,000 IU of Vitamin D (weekly or bi-weekly) – Meta-analysis July 2023 16 Aug, 2023
Sleep greatly improved by 50,000 IU of vitamin D once every two weeks – RCT Sept 2018 07 Aug, 2023
Pain not reduced by 60,000 IU monthly vitamin D (need 50,000 IU weekly) – RCT Aug 2023 22 Jul, 2023
How often might 50,000 IU vitamin D be taken - results of clinical trials 18 Jul, 2023
Gestational Diabetes reduced with 50,000 IU of vitamin D every 3 weeks and daily Calcium – RCT June 2014 17 Jul, 2023
Multiple Sclerosis fatigue reduced by weekly Vitamin D (50,000 IU) – June 2023 15 Jul, 2023
Multiple Sclerosis treated equally by UVB and weekly 50,000 IU of Vitamin D – RCT July 2023 18 Jun, 2023
Mild Obstructive Sleep Apnea decreased by 50,000 IU weekly vitamin D – June 2021 20 May, 2023
Chronic tonsillitis virtually eliminated in children by Vitamin D (50,000 IU weekly) – RCT May 2023 20 May, 2023
Breast Cancer trial using 50,000 IU Vitamin D weekly cancelled (no funding) 18 Apr, 2023
Urinary Incontinence reduced by 50,000 IU of vitamin D weekly (details behind paywall) – RCT Feb 2023 24 Feb, 2023
50,000 IU and other high dose vitamin studies 15 Jan, 2023
Can get 50,000 IU Vitamin D anywhere on the globe 21 Dec, 2022
50,000 IU Vitamin D weekly is often recommended 30 Nov, 2022
Diabetes prevented by 50,000 IU vitamin D monthly (Iran) – Jan 2022 03 Nov, 2022
COVID etc. prevented and treated with 50,000 IU Vitamin D capsules - July 2022 22 Jul, 2022
50,000 IU of Vitamin D weekly for 6 months after cardiac failure helps – RCT May 2022 11 Jun, 2022
50,000 IU capsules of Vitamin D can be obtained everywhere - Jan 2022 26 Jan, 2022
Poor odor detection if low Vitamin D, better after 50,000 IU weekly - July 2021 23 Jan, 2022
Resistance training can be aided by Vitamin D, 50,000 IU monthly is not often enough – RCT Dec 2021 11 Jan, 2022
50,000 IU Vitamin D weekly was the most popular for Breast Cancer - May 2020 30 Aug, 2021
Diabetes helped somewhat by weekly 50,000 IU of vitamin D (5 ways to improve) – RCT Aug 2021 19 Aug, 2021
Vitamin D for infections and COVID (50,000 IU weekly for 3 months) – July 2021 02 Aug, 2021
Yet another study confirms Depression is treated by weekly Vitamin D (50,000 IU)– RCT Dec 2019 09 Jul, 2021
Cognitive function of adult women improved in 3 months of 50,000 IU weekly Vitamin D – Jan 2019 09 Jul, 2021
Immune systems helped by 50,000 IU of vitamin D (weekly for 3 months) – May 2021 03 Jun, 2021
Peripheral diabetic neuropathy helped by weekly 50,000 IU vitamin D – Jan 2019 25 May, 2021
Depression treated by 50K IU Vitamin D weekly (but not 1,000 IU daily) – meta-analysis Jan 2021 25 Apr, 2021
Reduce COVID-19 risks with 50,000 IU Vitamin D doses 14 Mar, 2021
Stroke patients getting weekly 50,000 IU Vitamin D did better – trial March 2021 12 Mar, 2021
Weekly 50,000 IU was the most succesful way to restore vitamin D levels (football) - Aug 2020 08 Feb, 2021
Endometriosis treated by Vitamin D (50,000 IU bi-weekly) – RCT Jan 2021 30 Jan, 2021
Bone density improved by monthly 50,000 IU of vitamin D for 6 months – RCT Jan 2021 19 Jan, 2021
Migraine headaches reduced with 50,000 IU vitamin D weekly – RCT July 2015 14 Jan, 2021
Take 50,000 IU of Vitamin D weekly before and after COVID-19 vaccination 27 Dec, 2020
Trial: Can 50,000 IU of Vitamin D weekly help with Breast Cancer Chemotherapy - Early 2021 21 Dec, 2020
50,000 IU vitamin D weekly to avoid Osteroporosis after Breast Cancer - May 2020 26 Nov, 2020
BPH (PSA) decreased by Vitamin D (50,000 IU bi-weekly) – RCT Nov 2020 21 Nov, 2020
In Vitro Fertilization clinical trial using 50,000 IU of Vitamin D bi-weekly – Dec 2024 14 Sep, 2020
Newborn Vitamin D - single 50,000 IU is better than daily – RCT Sept 2016 25 Jul, 2020
Weekly 50,000 IU of vitamin D is again found to be good – RCT May 2020 27 May, 2020
Reduce Coronavirus risk with Vitamin D (50,000 IU once a week) 27 Mar, 2020
IBS diarrhea treated by weekly 50,000 IU of Vitamin D – RCT March 2020 25 Mar, 2020
50,000 IU Vitamin D weekly provided enough benefit for combat sport athletes – March 2020 21 Mar, 2020
Response by obese to weekly 50,000 IU of Vitamin D – May 2018 12 Feb, 2020
Irritable Bowel Syndrome treated by weekly 50,000 IU Vitamin D – RCT Feb 2019 18 Jan, 2020
Hip surgery with multiple doses of 50,000 IU of vitamin D weekly both before and after – RCT 2023 16 Jan, 2020
Obese lost more weight on diet if added 50,000 IU of vitamin D weekly – many RCTs 25 Dec, 2019
Obese taking 50,000 IU of vitamin D weekly lost more weight (again) – RCT Dec 2019 25 Dec, 2019
General Anxiety Disorder treated by weekly Vitamin D (50,000 IU -Omega-3, Mg also help) – Sept 2019 09 Dec, 2019
Cystic Fibrosis not helped by 50,000 IU of Vitamin D taken twice a month – RCT Feb 2019 01 Nov, 2019
Fibromyalgia treated with Vitamin D (50,000 IU weekly for 3 months) – 2016, 2017, 2018, 2019 19 Oct, 2019
PMS again significantly reduced by 50,000 IU of vitamin D (This time, every two weeks) – RCT Oct 2019 19 Oct, 2019
Depression decreased after vitamin D (50,000 IU weekly to elderly in the case) – RCT Oct 2019 17 Oct, 2019
Long-term neck and back pains greatly reduced by 50,000 IU of Vitamin D – 4 cases – Sept 2019 14 Sep, 2019
Hashimoto's thyroiditis helped by weekly 50,000 IU of vitamin D – RCT May 2019 10 Sep, 2019
Athletes helped by weekly 50,000 IU Vitamin D – RCT Aug 2019 10 Aug, 2019
Hay Fever treated by Vitamin D (50,000 IU weekly) – RCT July 2019 02 Aug, 2019
Urgency Urinary Incontinence in senior black women decreased 40 percent by weekly 50,000 IU vitamin D – RCT Dec 2018 07 Jul, 2019
Treating Vitamin D deficiency in senior women – such as 50,000 IU daily for 15 days then twice a month – Review April 2019 14 Jun, 2019
Grip strength following wrist fracture increased by 50,000 IU Vitamin D monthly – May 2019 09 May, 2019
PMS in teens reduced 3X by 50,000 IU vitamin D weekly – Jan 2018 23 Mar, 2019
Schizophrenia reduced by biweekly 50,000 IU Vitamin D and probiotics – RCT Feb 2019 21 Feb, 2019
Poor Vitamin D binding had 30 percent less response to Vitamin D (50,000 IU weekly) – Feb 2019 04 Feb, 2019
Sleep improved with 50,000 IU Vitamin D every two weeks – RCT Oct 2018 20 Dec, 2018
Depression probably treated by bi-weekly 50,000 IU of vitamin D - RCT 2020 05 Dec, 2018
50,000 IU of vitamin D weekly following cardiac failure helps – RCT 2014 24 Nov, 2018
Attention-Deficit Hyperactivity Disorder treated by weekly 50,000 IU of vitamin D – RCT Nov 2018 21 Nov, 2018
Diabetic nephropathy (Kidney) treated by 50,000 IU of vitamin D weekly – RCT Jan 2019 17 Nov, 2018
Diabetes treated if given enough vitamin D (example: 50,000 IU weekly) – review of RCT - Jan 2017 02 Nov, 2018
Depression in seniors treated by weekly 50,000 IU of vitamin D – RCT Sept 2018 15 Oct, 2018
50,000 IU of Vitamin D weekly for 9 weeks did not improve CVD – Aug 2018 28 Aug, 2018
Multiple Sclerosis treated by 50,000 IU Vitamin D bi-weekly plus Omega-3 – RCT July 2018 06 Jul, 2018
Asthma treated by daily 50,000 IU of Vitamin D – April 2018 24 Jun, 2018
Fibromyalgia pain substantially reduced by weekly Vitamin D (50,000 IU) – June 2018 23 Jun, 2018
Pancreatic Cancer stabilized by a woman taking 50,000 IU of vitamin D daily - 2016 03 Jun, 2018
Pregnancies helped a lot by Vitamin D (injection then 50,000 IU monthly) – RCT May 2018 28 May, 2018
Knee pain and depression reduced by monthly 50,000 IU vitamin D – RCT April 2018 21 Apr, 2018
50,000 IU vitamin D routinely given monthly in New Zealand senior homes since 2011– Dec 2016 07 Apr, 2018
IBS quality of life improved by vitamin D (50,000 IU every two weeks) – RCT May 2016 14 Mar, 2018
HbA1c levels (Diabetes) reduced by monthly 50,000 IU of vitamin D – Dec 2017 01 Mar, 2018
Cystic Fibrosis got some benefit from 50,000 IU of vitamin D weekly (need gut-friendly form) – Feb 2018 03 Feb, 2018
Hypertension not controlled by 26 ng of Vitamin D (50,000 IU bi-weekly A-A) – RCT Nov 2017 18 Nov, 2017
Vitamin D taken daily (4,000 IU) vs weekly (50,000 IU) – RCT 2019 23 Oct, 2017
Vitamin D supplementation for newborns – 400 IU daily vs 50,000 IU dose – RCT Sept 2016 21 Oct, 2017
Depression in adolescent girls reduced somewhat by 50,000 IU weekly for 9 weeks – July 2017 01 Sep, 2017
Sleep quality improved with 50,000 IU of vitamin D every two weeks – RCT May 2017 23 Aug, 2017
Preeclampsia reoccurred half as often if get 50,000 IU of Vitamin D every two weeks – Aug 2017 22 Aug, 2017
Vitamin D supplementation guidelines (adults – 50,000 IU per week) – Feb 2017 21 Aug, 2017
Hemodialysis patients (CKD) helped by weekly 50,000 IU of vitamin D – Jan 2017 27 Jul, 2017
Canadian grant funding lost for prescribing 50,000 IU of vitamin D – July 2017 23 Jul, 2017
Cervical lesions (precancerous, identified by pap smear) treated by bi-weekly 50,000 IU of vitamin D – RCT Feb 2017 22 Jul, 2017
Type 1 diabetes helped with 50,000 IU of vitamin D every two weeks – Nov 2014 20 Jul, 2017
Knee osteoarthritis treated with vitamin D, weekly 50,000 IU – May 2015 20 Jul, 2017
Chinese women in tropics needed 50,000 IU of Vitamin D monthly to keep above 30 ng – RCT May 2017 14 Jul, 2017
50,000 IU of vitamin D every two weeks – Jordan conclusion - RCT July 2017 08 Jul, 2017
Fertility marker (Anti-Müllerian Hormone) improved in a week by a single dose to 50,000 IU of vitamin D – RCT July 2017 08 Jul, 2017
Fibromyalgia treated with Vitamin D (50,000 IU weekly for 3 months) – Nov 2016 27 Jun, 2017
Many benefits of 50,000 IU vitamin D every two weeks (methadone treatment) – RCT June 2017 21 Jun, 2017
Don’t take a PRESCRIPTION of 50,000 IU of vitamin D – June 2017 05 Jun, 2017
Vitamin D – 50,000 IU monthly is enough if near the equator and have normal weight – May 2017 25 Apr, 2017
50,000 IU vitamin D weekly is safe and effective for Primary Hyperparathyroidism – Jan 2013 23 Jan, 2017
Pulmonary hypertension reduced in some people with weekly 50,000 IU vitamin D for 3 months – 2016 16 Jan, 2017
Juvenile Lupus fatigue reduced by vitamin D ( 50,000 IU weekly for 6 months) – RCT May 2015 24 Nov, 2016
Gestational Diabetes treated with 50,000 IU every two weeks – RCT Sept 2016 03 Sep, 2016
5,000 IU daily or 50,000 IU Vitamin D weekly repleted many dark skinned adolescents – RCT Dec 2015 06 Aug, 2016
Free Vitamin D in New Zealand to prevent falls in nursing homes (50,000 IU monthly) – June 2016 30 Jul, 2016
50,000 IU vitamin D daily in ICU greatly reduces number and cost of heart attacks – Nov 2015 24 Jun, 2016
Nursing home residents need Vitamin D 4,000 IU daily or 50,000 IU weekly – Jan 2016 25 May, 2016
IBS quality of life improved by vitamin D (50,000 IU weekly) – RCT May 2016 17 May, 2016
Prediabetics not helped by 50,000 IU of vitamin D weekly and Calcium– Jan 2013 03 Apr, 2016
New Zealand – new 50,000 IU vitamin D capsule has soy which can cause allergic reactions – March 2016 09 Mar, 2016
Knee osteoarthritis reduced somewhat by 50,000 IU vitamin D monthly (need more) – RCT Aug 2015 08 Mar, 2016
Pain of Diabetic Neuropathy reduced with weekly 50,000 IU vitamin D– CT Feb 2015 22 Oct, 2015
Vitamin D loading dose then weekly 50,000 IU not help (COPD) if very deficient – Oct 2015 16 Oct, 2015
Preeclampsia reduced by Vitamin D (50,000 IU bi-weekly) and Calcium – Oct 2015 15 Oct, 2015
Gestational diabetes reduced by just two 50,000 IU doses of vitamin D – RCT Nov 2014 02 Oct, 2015
Vitamin D more than 40 ng: 1300 IU 50% chance: 5,000 IU 80% chance - Aug 2014 13 Sep, 2015
Vitamin D levels of HIV and non HIV equally restored with 50,000 IU twice a week - July 2015 24 Jul, 2015
Diabetes not treated by MONTHLY 50,000 IU vitamin D (which is not quite enough) – May 2015 12 Jul, 2015
Diabetes RCT we expect to fail just 50,000 IU monthly - July 2014 12 Jul, 2015
No multiple sclerosis relapses during pregnancy if 50,000 IU of Vitamin D weekly – RCT April 2015 21 Jun, 2015
Near the end of pregnancy 50,000 IU vitamin D weekly was great – RCT April 2013 08 Jun, 2015
Pregnant mothers in Quatar needed more than weekly 50,000 IU Vitamin D – Nov 2013 28 Mar, 2015
Peripheral Neuropathy in type II Diabetes reduced a bit by 50,000 IU weekly of vitamin D – RCT Feb 2015 28 Mar, 2015
Lupus not treated by monthly 50,000 IU vitamin D (no surprise) – RCT April 2015 23 Mar, 2015
50,000 IU Vitamin D one time after birth helped – RCT Jan 2015 14 Jan, 2015
50,000 IU monthly safe to take without any vitamin D testing – RCT Dec 2013 22 Dec, 2014
Fibromyalgia pain with trazodone reduced by 50 percent with weekly 50,000 IU of vitamin D – RCT Nov 2014 22 Nov, 2014
Will vitamin D loading dose and 50,000 IU monthly will help after melanoma surgery – Oct 2014 24 Oct, 2014
Diabetes treated by 50,000 IU of vitamin D weekly with 1 g Calcium daily – RCT July 2014 14 Sep, 2014
7 improvements in lives of veterans with chronic pain with 50,000 IU vitamin D weekly – June 2012 20 Aug, 2014
Asthma reduced by weekly 50,000 IU of vitamin D – RCT Aug 2014 03 Aug, 2014
Vitamin D repaired nerve in rat (50,000 IU daily dose equivalent for human) – June 2013 28 Jun, 2014
Optic neuritis progession into Multiple Sclerosis reduced 68 percent by 50,000 IU of vitamin D weekly 08 May, 2014
COPD helped by weekly 50,000 IU Vitamin D – Aug 2013 03 May, 2014
7100 IU vitamin D (50,000 weekly) significantly reduced fibromyalgia – 2009 20 Jan, 2014
Need to adjust cofactors if take 50,000 IU of vitamin D weekly – Nov 2013 12 Jan, 2014
50,000 IU of vitamin D monthly in winter gets most above 20 ng – RCT Nov 2013 21 Dec, 2013
50,000 IU vitamin D weekly increased levels by 52 ng normally, but only 28 ng if obese – Oct 2013 13 Nov, 2013
50,000 IU vitamin D 1-3 times per week helped obese patients in rehab. – May 2013 01 Aug, 2013
50,000 IU vitamin D suggested to prevent osteoporosis (weekly then monthly)– April 2019 No value for 'modification_date_major'

VitaminDWiki – Health problems fought by 50,000 IU weekly:

ADHD,  Anxiety,  Asthma,  Autism,  Back Pain,  BPH (prostate),  Cancer - Breast,  Cancer - Colon,  Cancer - Prostate,  Cardiovascular,  Chronic Obstructive Pulmonary Disease,  Cognitive Decline,  Colds,  COVID,  Depression,  Diabetes,  Endometriosis,  Falls,  Fibromyalgia,  Hashimoto's Thyroiditis,  Hay Fever,  Heart Failure,  Hives,  Hypertension – Pulmonary,  Immune System,  Infant,  Inflammatory Bowel Syndrome,  Influenza,  Kidney Disease,  Knee-Pain,  Lupus,  Migraine,  Multiple Sclerosis,  Muscles - women, Obesity,  Pain - Chronic,  Pain - Growing,  PMS,  Preeclampsia,  Premature Birth,  Respiratory Tract Infection,  Schizophrenia,  Sleep-Poor,  Sleep Apnea,  Smoking,  Sports Performance,  Stroke,  Surgery,  Tonsilitis,  Tuberculosis,  Ulcerative Colitis,  Ulcers – Venous,  Urinary Tract Infection   click here for proof

75+ VitaminDWiki pages have Loading in the title

The list is automatically updated

Items found: 76
Title Modified
Vitamin D loading doses typically helped critically ill, but never harmed (21 RCTs) - Jan 2025 26 Jan, 2025
Loading dose of 60,000 IU Vitamin D once a week for 5 weeks safely raised deficient to above 30 ng – Nov 2024 05 Dec, 2024
Low Back Pain not helped by vitamin D if low dose or short duration (loading dose does help however) - meta-analysis Nov 2024 01 Nov, 2024
Loading dose of 300,000 IU Vitamin D got most above 20 ng in a week – Nov 2023 31 Jul, 2024
Cancer Immunotherapy is enhanced by a Vitamin D loading dose - Aug 2023 25 Jan, 2024
Breastfeeding Vitamin D loading dose of 300,000 IU is OK - UK govt. Dec 2023 04 Jan, 2024
Large Vitamin D loading doses recomended (Italy, goal 40-60 ng) - 2011 01 Jan, 2024
Vitamin D loading dose of 30,000 IU twice a week is safe and effective – RCT July 2023 22 Dec, 2023
Vitamin D 100,000 IU loading dose and stem cell transplants – RCT Oct 2023 31 Oct, 2023
Overview Loading of vitamin D 18 Jul, 2023
Fast responses to Vitamin D – loading dose, nanoemulsion and Calcifediol – April 2023 15 Apr, 2023
3,200 IU of Vitamin D for 3 weeks before colon cancer surgery helped a bit (higher or loading dose would be much better) – March 2023 31 Mar, 2023
Better Surgical outcomes if preceded by Vitamin D loading dose – Oct 2018 19 Oct, 2022
Loading Dose of Vitamin D 22 May, 2022
Loading dose of Vitamin D for patients hospitalized with COVID (140,000 IU) – RCT completed 2021 22 May, 2022
Small amounts of Vitamin D reduce Influenza risk by 22 percent (loading dose is far better) – meta-analysis Jan 2022 25 Jan, 2022
FLCCC COVID guidelines now include vitamin D loading doses - Jan 2022 20 Jan, 2022
Vitamin D loading doses quickly and safely raise levels – meta-analysis Dec 2021 03 Dec, 2021
Childhood cancers – give Vitamin D loading dose if low – Oct 2021 27 Oct, 2021
Stoss (loading) dose of vitamin D resulted in bigger response at 30 days (again) – RCT April 2021 14 Oct, 2021
Non-Alcoholic Fatty Liver Disease (NAFLD) treated by Vitamin D (20,000 IU weekly after loading dose) – RCT June 2016 05 Oct, 2021
Vitamin D and COVID, review of evidence, loading dose if less than 50 ng - Masterjohn Sept 2021 05 Sep, 2021
In-home testing of viral load, etc. Dr. Topol interview with transcript – Aug 11, 2021 14 Aug, 2021
Vitamin D loading dose was as effective as daily dosing (rickets in this case) – RCT July 2021 19 Jul, 2021
Omega-3 – most humans and horses can start with loading doses – saving 1 to 3 months 18 Apr, 2021
Respiratory Tract Infection risk reduced 2X by Vitamin D loading doses – meta-analysis Jan 2021 22 Jan, 2021
Vitamin D loading dose (stoss therapy) proven to improve health 13 Nov, 2020
ICU patients greatly helped by Vitamin D loading doses – if gut-friendly – Oct 2020 18 Oct, 2020
Vitamin D Replentishment (Loading doses are not toxic)– Feb 2012 04 Oct, 2020
Sickle cell Vitamin D deficiency corrected with 160 K IU loading dose – July 2014 25 Jul, 2020
Healthy in Seven Days - Loading dose of Vitamin D – book 2014 25 Jul, 2020
ICU survival increased with vitamin D single 540K IU loading dose - JAMA Sept 2014 25 Jul, 2020
300,000 IU injection loading dose of vitamin D3 stopped gestational diabetes in RCT – Oct 2011 25 Jul, 2020
Elderly Vitamin D Loading Dose of 500,000 IU is safe and effective – RCT 2009 12 Feb, 2020
Low trauma bone fractures in seniors – considering Vitamin D loading dose for all, without testing – Nov 2019 12 Nov, 2019
Ulcerative Colitis significantly reduced by 480,000 IU loading dose of nano Vitamin D – RCT July 2019 21 Sep, 2019
2X improved development by severely malnourished children with 2 loading doses of vitamin D – RCT May 2018 19 Jul, 2019
COPD quality of life improved by 400,000 IU Vitamin D loading dose – RCT July 2019 08 Jul, 2019
Call to action – more Vitamin D for pregnancies, loading doses are OK – Holick Aug 2019 25 Jun, 2019
Cerebral malaria deaths prevented by loading dose of vitamin D (mice) – Sept 2018 23 Sep, 2018
Vitamin D loading dose of 300,000 IU for children – 3 weeks with capsules, biscuits, injection – RCT Aug 2018 16 Aug, 2018
Post-birth stress index (allostatic load) – propose adding low Vitamin D as 11th item – April 2018 12 Apr, 2018
Total Testosterone, Erectile function scores, etc improved with loading dose of Vitamin D2 - Jan 2017 26 Sep, 2017
Rheumatoid Arthritis nicely treated by Vitamin D (300,000 IU loading dose) – May 2017 24 Jul, 2017
Bone health not improved in 2 months of Vitamin D (need 6 months or loading dose) – RCT April 2017 10 Jun, 2017
Vitamin D loading doses reduce ICU mortality by 30 percent – meta-analysis April 2017 20 May, 2017
Children in Intensive Care need Vitamin D loading dose of 10000 IU per kg (nearing a consensus) - Oct 2016 10 Apr, 2017
Vitamin D loading dose after hip fracture surgery was great – RCT Aug 2016 06 Apr, 2017
Vitamin D loading doses of up to 400,000 IU OK for adolescents – meta-analysis Dec 2014 19 Mar, 2017
Vitamin D supplementation protocols: loading, injection, etc – RCT June 2014 15 Mar, 2017
Quick restoration of vitamin D in children – 10,000 IU per kg loading dose was not enough – Jan 2017 06 Mar, 2017
300,000 IU loading dose of vitamin D does not help the obese much – Jan 2017 01 Feb, 2017
Knee osteoarthritis pain reduced by 60,000 IU monthly vitamin D following loading dose – RCT Nov 2013 24 Dec, 2016
Takes a year to restore children and youths to good levels of vitamin D without loading dose - RCT Dec 2016 19 Dec, 2016
Loading dose greatly improves subsequent daily Vitamin D if have liver fibrosis – RCT Nov 2016 18 Nov, 2016
Loading dose of 300,000 IU of vitamin D does not last long – March 2014 03 Nov, 2016
Neonate loading dose of 30,000 IU vitamin D helped a lot – May 2014 29 Oct, 2016
Vitamin D Loading dose - 20,000 IU daily is not enough if obese, etc. (Cancer) great table and chart – Oct 2016 08 Oct, 2016
Wisdom tooth (3rd molar) extraction helped by Vitamin D loading dose – RCT March 2016 17 Jul, 2016
Loading dose of Vitamin D2 REDUCED vitamin D blood in a third of the patients – Jan 2015 24 Mar, 2016
More stress (allostatic load biomarkers) associated with vitamin D deficiency – Oct 2015 17 Dec, 2015
Congenital Heart problems - vitamin D levels drop even lower after surgery, loading dose probably required - thesis 2015 07 Dec, 2015
Vitamin D loading dose then weekly 50,000 IU not help (COPD) if very deficient – Oct 2015 16 Oct, 2015
600,000 vitamin D loading doses – good response to both oral and muscular – Oct 2015 13 Oct, 2015
Lupus flares totally eliminated by loading dose then 100000 IU of vitamin D each month – Oct 2012 19 Dec, 2014
Will vitamin D loading dose and 50,000 IU monthly will help after melanoma surgery – Oct 2014 24 Oct, 2014
Osteoporosis Society UK: 20 ng vitamin D is sufficient, loading dose 300,000 IU – Sept 2014 17 Sep, 2014
Vitamin D for Italians – Senior 2300 IU, if deficient loading dose of at least 300,000 IU– Med Society 2011 19 Mar, 2014
Pre-diabetes was not helped by conventional vitamin D loading for 12 weeks – Jan 2013 29 Aug, 2013
Turkey prescribed 400 IU for all infants, with loading dose for those with rickets – 2005 24 Jun, 2013
Loading dose for Vitamin D 18 Feb, 2013
Variety of vitamin D loading dose recommendations in the UK - 2011 28 Oct, 2012
Loading dose of 300,000 IU vitamin D every 6 months – Dec 2011 31 Aug, 2012
Vitamin D3 much better than D2 for loading doses– meta-analysis May 2012 23 Jun, 2012
Vitamin D2 loading doses did not increase, and may have decreased blood levels– June 2011 29 Mar, 2012
Vitamin D3 loading dose of 500,000 IU for elderly – Aug 2009 07 Nov, 2011

Loading dose of 60,000 IU Vitamin D once a week for 5 weeks safely raised deficient to above 30 ng – Nov 2024        
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