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Little weight loss in obese children from very small amount of vitamin D (1200 IU) – RCT April 2020

Long-Term Effects of Vitamin D Supplementation in Obese Children During Integrated Weight–Loss Programme—A Double Blind Randomized Placebo–Controlled Trial

Nutrients 2020, 12(4), 1093; https://doi.org/10.3390/nu12041093
by Michał Brzeziński 1,2,*OrcID,Agnieszka Jankowska 1,Magdalena Słomińska-Frączek 3,Paulina Metelska 2,4,Piotr Wiśniewski 5,Piotr Socha 6 andAgnieszka Szlagatys-Sidorkiewicz 1OrcID


After 25 weeks, 1200 IU of vitamin D daily raised Vitamin D blood levels of obese children from 19 to 25 ng
Benefits of Vitamin D are rarely seen for any health problem if levels are <30 ng
This trial would have been successful if it had given at least:

Daily or Weekly
Children 2,000 IU 14,000 IU
Youths (heavier) 3,000 IU21,000 IU

Items in both categories Infant-Child and Obesity are listed here:

Items in both categories Intervention and Obesity are listed here:

 Download the PDF from VitaminDWiki

Background: Vitamin D was studied in regards to its possible impact on body mass reduction and metabolic changes in adults and children with obesity yet there were no studies assessing the impact of vitamin D supplementation during a weight management program in children and adolescence. The aim of our study was to assess the influence of 26 weeks of vitamin D supplementation in overweight and obese children undergoing an integrated 12–months’ long weight loss program on body mass reduction, body composition and bone mineral density.

Methods: A double–blind randomized placebo–controlled trial. Vitamin D deficient patients (<30 ng/ml level of vitamin D) aged 6–14, participating in multidisciplinary weight management program were randomly allocated to receiving vitamin D (1200 IU) or placebo for the first 26 weeks of the intervention.

Results: Out of the 152 qualified patients, 109 (72%) completed a full cycle of four visits scheduled in the program. There were no difference in the level of BMI (body mass index) change – both raw BMI and BMI centiles. Although the reduction of BMI centiles was greater in the vitamin D vs. placebo group (−4.28 ± 8.43 vs. −2.53 ± 6.10) the difference was not statistically significant (p = 0.319). Similarly the reduction in fat mass—assessed both using bioimpedance and DEXa was achieved, yet the differences between the groups were not statistically significant.

Conclusions: Our study ads substantial results to support the thesis on no effect of vitamin D supplementation on body weight reduction in children and adolescents with vitamin D insufficiency undergoing a weight management program.

Created by admin. Last Modification: Friday June 19, 2020 17:42:33 GMT-0000 by admin. (Version 7)

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