Gynecol Endocrinol. 2017 Aug;33(8):649-652. doi: 10.1080/09513590.2017.1306737. Epub 2017 May 3.
71% is unlikely to be just a chance
Even 61% would be also unlikely (p=.007)
- Birth rates doubled with Vitamin D - 300,000 for infertile men – RCT Nov 2017
- Poor fertility in both women and men associated with low vitamin D – review Feb 2018
- Global sperm count dropped by 59 percent in 40 years – meta-analysis Aug 2017
- Assisted Reproduction – 5 studies concluded vitamin D repletion helps – Review March 2015
- Vitamin D and Human Reproduction – 51 page chapter – April 2017
Fertility and Sperm category contains the following summary
Overview Women and Vitamin D
Overview Pregnancy and vitamin D Fertility and Vitamin D – several articles
Ensure a healthy pregnancy and baby - take Vitamin D before conception
IVF OR "IN VITRO FERTILIZATION" in 11 VitaminDWiki titles as of Jan 2022
Search VitaminDWiki for "Assisted reproduction" 177 items as of Sept 2019
Search VitaminDWiki for "polycystic ovary syndrome" OR PCOS" Sept 2019
Search VitaminDWiki fore Testosterone 77 items just in webpages as of Sept 2020
Search VitaminDWiki for "erectile dysfunction" 120 items as of July 2018
Conception and vitamin D snapshot as of 2012
Paffoni A1, Ferrari S1, Mangiarini A1, Noli S2, Bulfoni A3, Vigano P4, Parazzini F2, Somigliana E1,2.
1 Infertility Unit, Fondazione Ca' Granda, Ospedale Maggiore Policlinico , Milan , Italy.
2 Department of Clinical Sciences and Community Health , Università degli Studi di Milano , Milan , Italy.
3 Department of Obstetrics and Gynaecology , Humanitas Research Hospital , Milan , Italy , and.
4 Division of Genetics and Cell Biology , Reproductive Sciences Laboratory, IRCCS Ospedale San Raffaele , Milan , Italy.
A large number of evidence supports the role of vitamin D insufficiency in both women and men infertility. However, no studies have evaluated the rate of concordance of vitamin D status between the partners. This finding might open new scenarios in the interpretation of the available data linking vitamin D insufficiency and infertility. In the present cross-sectional study, 103 consecutive infertile couples were recruited between April and May 2014. Both partners concomitantly provided a serum sample for the assessment of 25-hydroxy-vitamin D 25-(OH)-D. Vitamin D insufficiency was defined as serum 25-(OH)-D <20 ng/ml. One hundred-fifty subjects (73 women and 77 males) were 25-(OH)-D insufficient, corresponding to a rate of 73%. Overall, concordance was observed in 73 couples (71%), thus higher than the expected 61% (0.732 + 0.272) based on chance (p = 0.007). The Pearson coefficient of correlation R2 between the partners of the couples was 0.52 (p < 0.001). No statistically significant differences emerged when evaluating the rate of 25-(OH)-D insufficiency according to the causes of infertility. Serum 25-(OH)-D correlates within the partners of infertile couples. Further evidence is warranted to determine the clinical relevance and possible clinical applications of this finding.
PMID: 28466668 DOI: 10.1080/09513590.2017.1306737
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