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ICU patients greatly helped by Vitamin D loading doses – if gut-friendly – Oct 2020

Meta-analysis on this page of all forms of Vitamin D did not find any benefit to ICU patients. ICU patients often have poor digestive systems, and so respond best to gut-friendly Vitamin D.

I have highlighted those gut-friendly RCTs using Vitamin D
Gut-friendly forms include:

  • Injection
  • IV
  • Topical
  • Emulsions
  • Mucous membranes in the mouth
  • Vaginal

Overview Gut and vitamin D contains gut-friendly information

Gut-friendly, Sublingual, injection, topical, UV, sunshine

Getting Vitamin D into your body has the following chart

Getting Vitamin D into your body also has the following
If poorly functioning gut
Bio-D-Mulsion Forte – especially made for those with poorly functioning guts, or perhaps lacking gallbladder
Sublingual – goes directly into the bloodstream
Fat-soluble Vitamins go thru the slow lymph system
   you can make your own sublingual by dissolving Vitamin D in water or use nano form
Oil: 1 drop typically contains 400 IU, 1,000 IU, or 4,000 IU, typically not taste good
Topical – goes directly into the bloodstream. Put oil on your skin, Use Aloe vera cream with Vitamin D, or make your own
Vaginal – goes directly into the bloodstream. Prescription-only?
Bio-Tech might be usefulit is also water-soluble
Vitamin D sprayed inside cheeks (buccal spray) - several studies
    and, those people with malabsorption problems had a larger response to spray
Inject Vitamin D quarterly into muscle, into vein, or perhaps into body cavity if quickly needed
Nanoparticles could be used to increase vitamin D getting to the gut – Oct 2015
Poor guts need different forms of vitamin D has the following
Guesses of Vitamin D response if poor gut

Bio FormSpeedDuration
10Injection ($$$)
or Calcidiol or Calcitriol
D - Slow
C -Fast
10 Sun/UVBSlowLong
(skin patch/cream, vagina)
Fast nano
9Nanoemulsion -mucosal
perhaps activates VDR
9?Inhaled (future)FastNormal
8Bio-D-Mulsion ForteNormalNormal
6Water soluble (Bio-Tech)NormalNormal
(some goes into gut)
3Coconut oil basedSlowNormal
2Food (salmon etc.)SlowNormal
2Olive oil based (majority)SlowNormal

10= best bioavailable, 0 = worst, guesses have a range of +-2
Speed: Fast ~2-6 hours, Slow ~10-30 hours
Duration: Long ~3-6 months, Normal = ~2 months

Vitamin D supplementation and the outcomes of critically ill adult patients: a systematic review and meta-analysis of randomized controlled trials – Oct 2020
Shao-Huan Lan,7, Chih-Cheng Lai,7, Shen-Peng Chang, Li-Chin Lu, Shun-Hsing Hung* & Wei-Ting Lin*
 Download the PDF from VitaminDWiki

Created by admin. Last Modification: Monday October 19, 2020 19:36:52 GMT-0000 by admin. (Version 4)

Attached files

ID Name Comment Uploaded Size Downloads
14439 ICU not gut.jpg admin 18 Oct, 2020 46.02 Kb 445
14438 Criticall Ill meta-analysis.pdf admin 18 Oct, 2020 1.74 Mb 453