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How We can fix this pandemic in a month (Vitamin D: 20K IU for 14 days) – June 22, 2020

Orthomolecular Medicine News Service

Commentary by Damien Downing, MBBS, MRSB


Opinions of vitamin D needed to PREVENT COVID-19 include

  • This commentary: 20,000 IU/day for 14 days then 4,000 IU daily
    • Note: 1/2 of the population needs more than 4,000 IU daily
  • 50,000 IU/day for 7 days then 50,000 IU weekly (= 7,000 IU daily)
  • VitaminDWiki: 400,000 IU once then 200,000 IU monthly (= 7,000 IU daily)
    • Thus, the estimated Vitamin D total doses needed for restoration:
      • 280,000 IU, 350,000 IU and 400,000 IU

Note: Need large doses if Overweight or Obese
Note: Need larger loading and maintenance doses to TREAT COVID-19

If we act on the data showing that it is highly probable that vitamin D can save lives, we could fix this pandemic in a month, for perhaps $2 per person. There would be no significant adverse effects. If we wait for "evidence" that vitamin D mitigates the impact of COVID-19, thousands more will die. If we could arrange to give everyone vitamin D, and it failed to protect them, so what? The risk from not acting is much greater than the risk from acting. Dosage is important and generally misunderstood.

Two countries have acted on this already: Egypt and Slovenia. Why can't we?

The Orthomolecular Medicine News Service has been publicizing the importance of vitamins D and C, and the minerals zinc and magnesium, in this pandemic since January [1]. I have been writing about Vitamin D and sunlight for over 30 years [2], and it has never been more relevant.

If you caught the COVID19 virus right now, having a good vitamin D status (from already having taken a supplement) would

  • Reduce your risk of the disease becoming severe by 90%
  • Reduce your risk of dying by 96%

This is not "proven" or "evidence-based" until we have done controlled trials comparing it to placebo. Any volunteers for that? But the data, already strong, has been pouring in since the start of the pandemic. Here's the data for the two statements above.

[A Hazard Ratio of 4 means that in one condition, for instance vitamin D deficiency, you are 4 times more likely to suffer the "hazard" than in another condition, say vitamin D adequacy. The graphics are all mine.]

A Philippine study [3]


With a deficient vitamin D status (<50nmol/L) the probability of becoming Severe or Critical with COVID-19 was 72.8% against 7.2% with adequate vitamin D (>75nmol/L). The Hazard Ratio is 10.0.

An Indonesian study [4]

With a deficient vitamin D status (<50nmol/L) the mortality rate from COVID-19 was 98.8% against 4.1% with adequate vitamin D (>75nmol/L). The Hazard Ratio is 24.1.

A review of data on Europe [5]

For countries in Europe, the probability of developing COVID-19, and of dying from it, is negatively correlated with mean population vitamin D status, with both probabilities reaching zero above about 75nmol/L. (The chart also shows the lower vitamin D levels for the elderly in Spain and Italy. [6]) It is also known that other factors such as age, hypertension, and cardiovascular disease, obesity, and diabetes are commonly associated with death in COVID-19. [5-8] For example, the elderly population in care facilities often do not get much sunlight exposure nor adequate supplements of essential nutrients including vitamin D, which will increase their risk of serious infections. Further, the 25(OH)D level in northern European countries such as Sweden drops in late winter to ~50 nmol/L or less, which may explain their relatively high death rate from infection. [9]

Dosage is important and generally misunderstood
Recent studies have suggested in discussion that more than 4000 IU per day of vitamin D3 may carry a risk of harm, citing the UK Scientific Advisory Committee on Nutrition report of 2016 which set the recommended Upper Level (UL) intakes of 50mcg/2000IU per day. [10] That report says; "Excessive vitamin D intakes have, however, been shown to have toxic effects (Vieth, 2006)". [10] However this is misleading, as the Vieth paper [11] states: "Published reports suggest toxicity may occur with 25(OH)D concentrations beyond 500 nmol/L." This leaves a wide margin of safety.

The 3 papers mentioned above [3-5] show that a vitamin D3 blood level of at least 75 nmol/L (30 ng/ml) is needed for protection against COVID-19. Government recommendations for vitamin D intake - 400 IU/day for the UK and 600 IU/day for the USA (800 IU for >70 years) and the EU - are based primarily on bone health. This is woefully inadequate in the pandemic context. An adult will need to take 4000 IU/day of vitamin D3 for 3 months to reliably achieve a 75 nmol/L level [12]. Persons of color may need twice as much [13]. These doses can reduce the risk of infection, but are not for treatment of an acute viral infection. And since vitamin D is fat-soluble and its level in the body rises slowly, for those with a deficiency, taking a initial dose of 5-fold the normal dose (20,000 IU/day) for 2 weeks can help to raise the level up to an adequate level to lower infection risk.

Other essential nutrients can help
As mentioned above, many studies have shown that for those deficient in essential nutrients, a protocol that includes vitamin D, vitamin C, magnesium, and zinc can decrease the risk of infection for viruses, including those similar to COVID-19.[1] Recommended preventive adult doses are vitamin C, 3000 mg/day (in divided doses, to bowel tolerance), magnesium, 400 mg (in malate, citrate, or chloride form), zinc, 20 mg. [1]


Nutritional Medicine is Orthomolecular Medicine
Orthomolecular medicine uses safe, effective nutritional therapy to fight illness.

For more information: http://www.orthomolecular.org

Find a Doctor: To locate an orthomolecular physician near you: http://orthomolecular.org/resources/omns/v06n09.shtml

The peer-reviewed Orthomolecular Medicine News Service is a non-profit and non-commercial informational resource.

COVID-19 treated by Vitamin D - studies, reports, videos in VitaminDWiki follows

As of Jan 26 had:  34 trials4 trial results,  13 meta-analyses and reviews,   46 observations,   26 recommendations,   42 associations,  84 speculations,  38 videos   see also COVID-19 and Vitamin D:   Governments.   Health problems.   Hospitals

Top Vitamin D and COVID-19 recent updates


Intervention Trial Summary Table
Details on #5 = COVIT-TRIAL Dec 27
Note: >70% of the RCT using Vitamin D to fight COVID-19 are using at least 100,000 IU during the first week
RCTs for COVID-19



Trial Results

Virus meta-analyses and Systematic Reviews

Observe - Less likely to become infected

short URL to this section = https://is.gd/COVID_less

Observe - Reduced Severity/Death

MORTALITY AND Virus (automatically updated):


Vitamin D Dosing Recommendations for COVID-19

Some people wanted improved immune systems, so took more vitamin D

COVID-19 associated with Low Vitamin D

Vitamin D levels are lower in those who test positive for COVID-19 -[doi:10.3390/nu12051359| Nutrients] May 09

    • Image
  • [https://articles.mercola.com/sites/articles/archive/2020/05/08/vitamin-d-level-correlated-to-covid19-outcomes.aspx?cid_source=dnl&cid_medium=email&cid_content=art1HL&cid=20200508Z1&et_cid=DM527863&et_rid=867359477 |Vitamin D Level Is Directly Correlated to COVID-19 Outcome] Mercola May 8
    • Overview of many studies and video by Ivor Cummins
  • [https://www.sciencedaily.com/releases/2020/05/200507131012.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine%2Fvitamin_d+%28Vitamin+D+News+--+ScienceDaily%29 |Vitamin D linked to low virus death rate in 20 countries in Europe] Science Daily May 7
  • [https://doi.org/10.1101/2020.05.01.20087965 |Evidence Supports a Causal Model for Vitamin D in COVID-19 Outcomes] May 6 preprint
    • Excellent extensive use of Causal Influence AI to discover associations.
    • I have suspected that Causal Influence could be much better, far lower cost, and faster than the use of RCTs
  • [https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3586555|Evidence of Protective Role of Ultraviolet-B (UVB) Radiation in Reducing COVID-19 deaths] preprint May 7
    • "permanent unit increase in UVI is associated with a 2.2 % decline in daily growth rates of cumulative COVID-19 deaths [p < 0.01]
    • as well as a 1.9 % decline in the daily growth rates of CFR [p < 0.05]
    • 64 countries, 78 days, 6 UVI models
  • [https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3593258#.XrE0oF1wSjU.twitter |Vitamin D Level of Mild and Severe Elderly Cases of COVID-19: A Preliminary Report] May 5
    • 176 seniors in S. Asia - published in India
    • Image
  • Almost everyone with COVID-19 in a Louisiana ICU had low vitamin D – April 29, 2020
  • COVID-19 mortality rate highest North of 35 degrees latitude (Vitamin D) – April 20, 2020
  • COVID-19 was 19X more likely if low vitamin D (may be invalid data)– April 2020 Philippines
    • The raw data has strange gaps in the vitamin D levels
    • Image
  • Research Suggests a Link Between Vitamin D Deficiency and COVID-19 Deaths May 5
  • Indonesia preprint 13X if vitamin D insufficient,19X for patients who are vitamin D deficient.
    • VitaminDWiki has requested but has not yet access to the raw data
  • COVID-19 infections associated with very low vitamin D – Turin Italy – March 2020



click here to see earlier speculations





Groups which actively ignore Vitamin D possibility

  • The Wellcome-Gates COVID-19 Accelerator initiative expressly prohibits funding for Vitamins.

Why/How Vitamin D both treats and prevents virus

File not found.

Short URL for this section = https://is.gd/covitamind

Created by admin. Last Modification: Tuesday June 23, 2020 01:11:54 GMT-0000 by admin. (Version 8)

Attached files

ID Name Comment Uploaded Size Downloads
13944 Ortho Europe.jpg admin 22 Jun, 2020 23:26 32.85 Kb 389
13943 Ortho Indonesia.jpg admin 22 Jun, 2020 23:25 21.25 Kb 390
13941 Ortho Phil.jpg admin 22 Jun, 2020 23:22 32.65 Kb 426
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