Orthomolecular Medicine News Service
Commentary by Damien Downing, MBBS, MRSB
Opinions of vitamin D needed to PREVENT COVID-19 include
- This commentary: 20,000 IU/day for 14 days then 4,000 IU daily
- Note: 1/2 of the population needs more than 4,000 IU daily
- 50,000 IU/day for 7 days then 50,000 IU weekly (= 7,000 IU daily)
- VitaminDWiki: 400,000 IU once then 200,000 IU monthly (= 7,000 IU daily)
- Thus, the estimated Vitamin D total doses needed for restoration:
- 280,000 IU, 350,000 IU and 400,000 IU
- Thus, the estimated Vitamin D total doses needed for restoration:
Note: Need large doses if Overweight or Obese
Note: Need larger loading and maintenance doses to TREAT COVID-19
If we act on the data showing that it is highly probable that vitamin D can save lives, we could fix this pandemic in a month, for perhaps $2 per person. There would be no significant adverse effects. If we wait for "evidence" that vitamin D mitigates the impact of COVID-19, thousands more will die. If we could arrange to give everyone vitamin D, and it failed to protect them, so what? The risk from not acting is much greater than the risk from acting. Dosage is important and generally misunderstood.
Two countries have acted on this already: Egypt and Slovenia. Why can't we?
The Orthomolecular Medicine News Service has been publicizing the importance of vitamins D and C, and the minerals zinc and magnesium, in this pandemic since January [1]. I have been writing about Vitamin D and sunlight for over 30 years [2], and it has never been more relevant.
If you caught the COVID19 virus right now, having a good vitamin D status (from already having taken a supplement) would
- Reduce your risk of the disease becoming severe by 90%
- Reduce your risk of dying by 96%
This is not "proven" or "evidence-based" until we have done controlled trials comparing it to placebo. Any volunteers for that? But the data, already strong, has been pouring in since the start of the pandemic. Here's the data for the two statements above.
[A Hazard Ratio of 4 means that in one condition, for instance vitamin D deficiency, you are 4 times more likely to suffer the "hazard" than in another condition, say vitamin D adequacy. The graphics are all mine.]
A Philippine study [3]
With a deficient vitamin D status (<50nmol/L) the probability of becoming Severe or Critical with COVID-19 was 72.8% against 7.2% with adequate vitamin D (>75nmol/L). The Hazard Ratio is 10.0.
An Indonesian study [4]
With a deficient vitamin D status (<50nmol/L) the mortality rate from COVID-19 was 98.8% against 4.1% with adequate vitamin D (>75nmol/L). The Hazard Ratio is 24.1.
A review of data on Europe [5]
For countries in Europe, the probability of developing COVID-19, and of dying from it, is negatively correlated with mean population vitamin D status, with both probabilities reaching zero above about 75nmol/L. (The chart also shows the lower vitamin D levels for the elderly in Spain and Italy. [6]) It is also known that other factors such as age, hypertension, and cardiovascular disease, obesity, and diabetes are commonly associated with death in COVID-19. [5-8] For example, the elderly population in care facilities often do not get much sunlight exposure nor adequate supplements of essential nutrients including vitamin D, which will increase their risk of serious infections. Further, the 25(OH)D level in northern European countries such as Sweden drops in late winter to ~50 nmol/L or less, which may explain their relatively high death rate from infection. [9]
Dosage is important and generally misunderstood
Recent studies have suggested in discussion that more than 4000 IU per day of vitamin D3 may carry a risk of harm, citing the UK Scientific Advisory Committee on Nutrition report of 2016 which set the recommended Upper Level (UL) intakes of 50mcg/2000IU per day. [10] That report says; "Excessive vitamin D intakes have, however, been shown to have toxic effects (Vieth, 2006)". [10] However this is misleading, as the Vieth paper [11] states: "Published reports suggest toxicity may occur with 25(OH)D concentrations beyond 500 nmol/L." This leaves a wide margin of safety.
The 3 papers mentioned above [3-5] show that a vitamin D3 blood level of at least 75 nmol/L (30 ng/ml) is needed for protection against COVID-19. Government recommendations for vitamin D intake - 400 IU/day for the UK and 600 IU/day for the USA (800 IU for >70 years) and the EU - are based primarily on bone health. This is woefully inadequate in the pandemic context. An adult will need to take 4000 IU/day of vitamin D3 for 3 months to reliably achieve a 75 nmol/L level [12]. Persons of color may need twice as much [13]. These doses can reduce the risk of infection, but are not for treatment of an acute viral infection. And since vitamin D is fat-soluble and its level in the body rises slowly, for those with a deficiency, taking a initial dose of 5-fold the normal dose (20,000 IU/day) for 2 weeks can help to raise the level up to an adequate level to lower infection risk.
Other essential nutrients can help
As mentioned above, many studies have shown that for those deficient in essential nutrients, a protocol that includes vitamin D, vitamin C, magnesium, and zinc can decrease the risk of infection for viruses, including those similar to COVID-19.[1] Recommended preventive adult doses are vitamin C, 3000 mg/day (in divided doses, to bowel tolerance), magnesium, 400 mg (in malate, citrate, or chloride form), zinc, 20 mg. [1]
References
- 1. Saul AW. (2020) Vitamin C Protects Against Coronavirus. Orthomolecular Medicine News Service http://orthomolecular.org/resources/omns/v16n04.shtml
- 2. Downing D. (1988) Day Light Robbery. Arrow Books, London. ISBN-13: 978-0099567400
- 3. Alipio MM. (2020) Vitamin D supplementation could possibly improve clinical outcomes of patients infected with Coronavirus-2019 (COVID- 2019). Preprint available at SSRN: https://ssrn.com/abstract=3571484
- 4. Raharusuna P, Priambada S, Budiarti C et al. (2020) Patterns of COVID-19 Mortality and Vitamin D: An Indonesian Study.
- 5. Ilie, P., Stefanescu, S., Smith, L. (2020) The role of Vitamin D in the prevention of Coronavirus Disease 2019 infection and mortality. Research Square preprint. https://europepmc.org/article/ppr/ppr147305
- 6. Lips P, Cashman K, Lamberg-Allardt C et al (2019) Current vitamin D status in European and Middle East countries and strategies to prevent vitamin D deficiency: a position statement of the European Calcified Tissue Society. Eur J Endocrinol. 180:23-54. https://europepmc.org/article/MED/30721133
- 7. Oaklander M (2020) Almost Every Hospitalized Coronavirus Patient Has Another Underlying Health Issue, According to a Study of New York Patients. Time Magazine, April 22, 2020. https://time.com/5825485/coronavirus-risk-factors
- 8. Richardson S, Hirsch JS, Narasimhan M. (2020) Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area. JAMA. 323:2052-2059. https://jamanetwork.com/journals/jama/fullarticle/2765184
- 9. Klingberg E, Oleröd G, Konar J, et al. (2015) Seasonal variations in serum 25-hydroxy vitamin D levels in a Swedish cohort. Endocrine, 49:800-808. https://pubmed.ncbi.nlm.nih.gov/25681052
- 10. UK Scientific Advisory Committee on Nutrition (SACN) (2016) Vitamin D and Health. https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/537616/SACN_Vitamin_D_and_Health_report.pdf
- 11. Vieth R (2006) Critique of the considerations for establishing the tolerable upper intake level for vitamin D: critical need for revision upwards. J Nutr, 136:1117-1122. https://pubmed.ncbi.nlm.nih.gov/16549491
- 12. Vieth R, Chan PC, MacFarlane GD. (2001) Efficacy and safety of vitamin D(3) intake exceeding the lowest observed adverse effect level. Am J Clin Nutr, 73:288-294. https://pubmed.ncbi.nlm.nih.gov/11157326
- 13. Cashman KD, Ritz C, Adebayo FA, et al. (2019) Differences in the dietary requirement for vitamin D among Caucasian and East African women at Northern latitude. Eur J Nutr. 58:2281-2291. https://pubmed.ncbi.nlm.nih.gov/30022296
Nutritional Medicine is Orthomolecular Medicine
Orthomolecular medicine uses safe, effective nutritional therapy to fight illness.
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COVID-19 treated by Vitamin D - studies, reports, videos in VitaminDWiki follows
As of Augest 11, 2022, the VitaminDWiki page had: 34 trials, 11 trial results, 37 meta-analyses and reviews, 69 observations, 38 recommendations, 55 associations, 89 speculations, 58 videos, 45 Mortality studies see related: Governments, HealthProblems, Hospitals, Dark Skins, 26 risk factors are ALL associated with low Vit D, Recent Virus pages Fight COVID-19 with 50K Vit D weekly Vaccines Take lots of Vitamin D at first signs of COVID 116 COVID Clinical Trials using Vitamin D (08/2022)
5 most-recently changed Virus entries
Top Vitamin D and COVID-19 recent
- Vitamin D can provide HEALTH immunity to fight the Corona virus this fall - Aug 2022
- Super-immune do not get COVID symptoms (perhaps Vitamin D) - Aug 2022
- COVID children helped by Vitamin D, trial terminated: unethical to not give Vitamin D to all: – RCT July 2022
- Current Compherensive Approach to COVID-19 (293 pages) - July 2022
- Some countries give treatment kits containing vitamin D if test positive for COVID) - July 2022
- Elderly who had been in COVID ICU were 4X more likely to die if low vitamin D – Nov 2022
- ‘Pandemic of the Boosted’: UK Data Reveal Problem With COVID Vaccinations - July 2022
- Pandemic Vitamin D levels dropped by 3.3 ng (perhaps less D, more health problems) – May 2022
- Long-COVID is now the biggest COVID concern (there are solutions) – July 2022
- Severe COVID 2.6 X less likely if supplement with Vitamin D – 26th meta-analysis - July 2022
- Calcifediol is in the title of 7 virus pages as of June 2022
- Some COVID hospitalizations are due to poor Vitamin D genes (Binding Protein in this commentary) – June 2022
- COVID, Cancer, etc. are Vitamin D low-hanging-fruit – Editorial June 2022
- COVID deaths are often of fully vaccinated in fully vaccinated countries – June 2022
- Both Omicron and Monkeypox show evidence of mutation by the human immune system – June 2022
- Treat COVID early with high-dose Vitamin D (20th as of June 2022)
- Vitamin D might mitigate endemic COVID - June 2022
- Vitamin D also provides COVID Neuroprotection – April 2022
- 89% are vaccinated, but Omicron BA.5 is surging (Portugal) June 2022
- COVID hospital deaths reduced 2X by 8 days of UVB – pilot RCT May 2022
- Surviving COVID with vitamins and minerals is not a myth – June 2022
- Vitamin D is the only one which: 1) Can be done at home, 2) Needs only a single dose
- 400,000 IU of vitamin D 3 days after COVID symptoms reduced 14 day mortality by 3X – Annweiler RCT May 2022
- Patients hospitalized with COVID not helped by 500,000 IU of Vitamin D – RCT – May 2022
- Suspect that they did not get the Vitamin D until 1 week after getting symptoms
- both groups had adequate vitamin D levels upon entering hospital
- COVID-19 Is Treatable and Preventable With Vitamin D: Dr. Malone - May 24, 2022
- Less COVID if more vitamin D from food (Spain) – May 2022
- You Are Going to Get COVID Again … and Again … and Again once every 3 years
- Unless you take Vitamin D
- Omicron BA.2.12.1 - US dominate form,100,000 cases daily - May 24, 2022
- Problems after childhood vaccinations - many studies - perhaps fewer problems if more Vitamin D
- Loading dose of Vitamin D for patients hospitalized with COVID (140,000 IU) – RCT completed 2021
- COVID Ventilation 2X less likely if 200,000 IU of Vitamin D when enter hospital – May 2022
- COVID in seniors 5X less likely to be severe if vegetarian (small study) – April 2022
- Inhaling Nitric Oxide 4 times a day (which increases Vitamin D) fights COVID - May 2022
- Forecast of 100 million more US COVID infections in fall and winter - May 2022
- Vitamin D, Immune function, and SARS-CoV2 – May 2022
- COVID death 5.2X more likely if Vitamin D deficient – May 2022
- Severe COVID while pregnant - none had taken any vitamin D – Oct 2021
- Risk factors for severe COVID in children are all related to low vitamin D (same as adults) - April 2022
- Innate immune suppression by SARS-CoV-2 mRNA vaccinations - April 2022
- Dr. McCullough is one of the authors, in-depth look at VARS 2021 data
- COVID death 6.9X less likely if high Magnesium to Calcium ratio – April 2022
- 13 Magnesium and COVID studies in VitaminDWiki
- 21 fewer days in hospital with ARDS (COVID) if 10,000 IU of Vitamin D daily after enter hospital – RCT April, 2022
- Speculation: "No hospitalization if had gotten high dose vitamin D at COVID symptom onset"
- 4X less likely to get COVID following 4,000 IU daily for a month – RCT April 2022
- COVID and CVD deadly pandemics share a risk factor: low vitamin D - April 2022
- 29 X more likely to die of COVID if less than 20 ng of Vitamin D - March 2022
- 2.9 X less risk of COVID ICU if seniors had supplemented with Vitamin D (any amount) – April 2022
- Data from Spring of 2020. Wonder why the 2 year delay
- Micronutrients such as vitamin D should improve vaccine effectiveness (and decrease side effects) – April 2022
- High altitudes reduce the COVID-19 infection (not a surprise) – April 2022
- Obesity, Hypovitaminosis D, and COVID-19 – April 2022
- COVID while pregnant: 2.6 X more likely to be Vitamin D deficient (need to supplement) - March 2022
- Pfizer vaccine produced 30 percent more antibodies if more vitamin D – July 2022
- COVID-XE variant can probably be fought by strong immune systems (Vitamin D, etc.) - April 2022
- COVID Long-Haul at 49 weeks: overactive immune system, type O blood - March 2022
- CDC and UK data reveal the COVID vaccines do not prevent cases, transmission, severe illness or deaths - April 3, 2022
- Children have less severe COVID, but just as much long-haul as adults - April 2022
- COVID-XE variant can probably be fought by strong immune systems (Vitamin D, etc.) - April 2022
- COVID breakthru 2X more likely if pregnant (should take Vitamin D) - April 2022
- COVID, like influenza, may be able to mutate to avoid vaccines for decades - March 2022
- Increase in COVID Omicron deaths among vaccinated (CA this time) - March 2022
- Risk of COVID not reduced by 3,200 IU of vitamin D for 6 months (no surprise) – RCT March 2022
- COVID length of stay: the best predictor was Vitamin D (of 70 parameters) – March 2022
- Review of Early Treatments of COVID-19 (within a few days of symptoms)
- Omicron-1 survives on surfaces 3X longer than original - March 18, 2022
- Compare symptoms of Omicron, Flu and Colds Vitamin D fights all of them
- Immune system both activates and uses vitamin D (in brain, fight COVID, etc.) - March 2022
- COVID length of stay: The best predictor was Vitamin D (of 70 parameters) – March 2022
- COVID: most places are dropping restrictions, some are surging, and a few are both - March 15, 2022
- Giving Vitamin D often reduced COVID Mortality– Review of 11 studies – March 2022
- 18 million excess global deaths in past 2 years: COVID plus collateral damage - Lancet March 2022
- decreased Vitamin D due to lock-up is one of the possible causes
- Vitamin D of 30-40 ng fights COVID, Dr. Grimes on Liverpool Study - March 2022
- Vitamin D separately helps X or COVID, should help X with COVID (example: diabetes) – March 2022
- Recall: 26 health problems associated with increased COVID risk, ALL are assoicated with low vitamin D
- COVID can be fought by healthy immune systems (vitamins, etc.) - Feb 2022
- Note elsewhere: Vitamin D improved immune system so much that half did not even test positive 24th meta-analysis
- Vitamin D helps both the innate and adaptive immune systems fight COVID-19 – Jan 2022
- Only a single supplement taken before infection decreased COVID severity (vitamin D) – Feb 2022
- COVID children with multisystem inflammatory syndrome have less than 10 ng of vitamin D – March 2022
- Vitamin D supplementation reduced risk of COVID-19 ICU by 2.8 X – review of 10 reviews Feb 2022
- COVID vaccination makes 6X more antibodies in those having good levels of both vitamin D and Iron – June 2021
- VitaminDWiki interview and transcript - Jan 2022 143 minute - includes a section on early treatments for COVID
- 14 X less likely to have severe COVID if previously had more than 40 ng level of Vitamin D – Feb 2022
- How vitamins A, B, C, D, E, F (Omega), K fight COVID - Feb 2022
- Estrogen supplements may cut COVID-19 deaths by half (no surprise - more E, more Vitamin D) - Feb 2022
- Group achieving 30 ng (vs 26 ng) were 2X less likely to get COVID symptoms - RCT Jan 2022
- Vitamin D helps both the innate and adaptive immune systems fight COVID-19 – Jan 2022
- COVID test positive is about half as likely if have Vitamin D – 24th meta-analysis - Jan 2022
- FLCCC COVID guidelines now include vitamin D loading doses - Jan 2022
- Vitamin D and its’ role in Parkinson’s disease patients with COVID - Jan 2022
- COVID death rate was 3X lower in those with Multiple Sclerosis (85 pcnt were taking Vitamin D) - Jan 2022
- Vitamin D fights COVID (54 studies of 1,400,000 people) – 23rd meta-analysis - Dec 2021
- Vitamin D benefits ignored at a time they are most needed - Grant Jan 9, 2022
- Increase in non-COVID deaths (ages 18-64) in Indiana, India, etc. - Jan 5, 2022
- Vitamin D and COVID-19: a narrative review - Holick - Jan 4, 2022
- Two times less likely to test positive for COVID if vitamin D level more than 55ng, etc. – Dec 31, 2021
- Vitamin D and COVID - Davies, Benskin (Dark Horse video with transcript) - Dec 27, 2021
- Ivermectin taken before COVID decreased death rate by 68 percent (3,000 with Ivermectin vs 3,000 without) - Dec 24, 2021
- The Vitamin D Receptor is associated with many health problems perhaps SARS-COV-2 as well
- Dr. McCullough on COVID-19: vaccine problems, home treatment – video, transcript – Dec 13, 2021
- Far fewer vaccination antibodies against Omicron - Dec 14, 2021
- Did HIV help Omicron evolve - Dec 10, 2021
- COVID-19 death increased 2X if low Vitamin D (less than 10 to less than 30 ng) – 21st meta-analysis Dec 2021
- Most COVID patients had sticky blood platelets (Omega-3 helps) - Dec 2021
- 16,000 Physicians and Scientists Agree Kids Shouldn’t Get COVID Vaccine - Dec 15, 2021
- Florida A.G. recommends Vitamin D, Zinc, Quercetin, etc. to reduce risk of COVID - Dec 12, 2021
- Vitamin D and a Dr. in Israel - Campbell video and transcript - Dec 11, 2021
- Epstein-Barr Virus may cause Long-Haul, CFS, and MS (Vitamin D should help)
- Pfizer knew of 290 kinds of COVID vaccine problems
- Vaccinated have HIGHER infection rates than unvaxxed (UK age 30-70) - Dec 9, 2021
- Rapid Vitamin D Delivery May Result in Better COVID Outcomes - Dec 9, 2021
- 11,321 Breakthru COVID cases in Massachusetts last week (fully vaccinated) - Dec 7, 2021
- COVID vaccines produce blood antibodies, not the needed mucosal antibodies - Dec 7, 2021
- also has several Vitamin D & COVID videos
- Coronaviruses evolve faster with vaccinations, expect more beyond Omicron - Nov 30, 2021
- Omega-3 decreases heart disease and COVID: Harris and Patrick, video and transcript - Dec 2021
- COVID is also associated with low Vitamin K - many studies
- Compulsory COVID Interventions do not work (400 studies - GreenMed Info) Dec 1, 2021
- Vitamin D loading doses quickly and safely raise levels – meta-analysis Dec 2021
- Real Anthony Fauci - book synopsis by Masterjohn Dec 3, 2021
- Large dose of calcifediol or vitamin D up to 15 days before COVID hospitalization reduced death rates (1.5X, 1.3X) – Dec 2021
- COVID-19 infection risk 2X higher in vaccinated than previously infected (28,000 in Netherlands) – preprint Nov 24, 2021
- Higher COVID death rates in more obese counties - Dec 2021
- COVID Virus kept mutating for 154 days in an immunocompromised person – Dec 2020
- COVID-19 risk reduction by Vitamin D, etc. - Grassroots Health Nov 29, 2021
- Vitamin D appears to drop while fighting COVID but recover later – Nov 2021
- How obesity reduces the ability of vitamin D to fight health problems such as COVID - Nov 2021
- Vaccinated were 28 percent of cases, 23 percent of deaths (waning)- CDC Sept 2021
- 11 percent fewer COVID-19 deaths if lockdowns had allowed sunshine – Nov 2021
- Long-Haul COVID is somewhat less of a problem if vaccinated – Nov 2021
- Elderly vaccinated for COVID were 2X more likely to die of ischemic stroke (2930 vs 1180 deaths)– Nov 2021
- Younger are much less likely to die of COVID than elderly (posters) - Nov 2021
- 3.3 X more likely to die if infected with SARS-Cov-2 plus a second pathogen – meta-analysis May 2021
- Pfizer trial vaccinated 22,000: 1 COVID death prevented, but 4 died of heart attacks - Nov 2021
- Problems with vaccine use during a pandemic - Dr. Bossche 2021, 2022
- 3,900 deaths within 2 weeks of 2nd vaccination in Sweden - Nov 18, 2021
- Discussion of COVID and 50 ng of Vitamin D (video and transcript)– Dr. Campbell Nov 17, 2021
- Vaccine definition by the CDC seems to now include Vitamin D - Sept 2021
- US is buying 5 billion dollars of Pfizer COVID pills (10 million dollars of Vitamin D might do as well) - Nov 2021
- Vaccination immunity is waning - Fauci - Nov 14, 2021
- Low Vitamin D etc. more than 3 months after COVID hospitalization – Sept 2021
- Bill Gates admits COVID-19 vaccines don't stop viral transmission - Nov 5, 2021
- COVID, influenza, hepatitis B, measles, etc. vaccine responses vary with Vitamin D and its receptor
- 2X more male teens died than normal in England this summer (perhaps vaccination) - Oct 2021
- Vaccine passports expire in 6 months in Israel, but not (yet) in the US - Oct 2021
- COVID probably fought by Vitamin D, might need 50 ng - Dr. Patrick Nov 8, 2021
- COVID-19 risk reduced by vitamin D supplementation – umbrella review of 7 meta-analysis – Oct 2021
- Perhaps 3X more likely to catch COVID-19 in a group (church) in Nov 2021 than Nov 2020
- Vaccination effectiveness dropped from 83 percent to ZERO after 9 months (Sweden, preprint) – Oct 2021
- COVID natural Immunity is most likely better than vaccination immunity- literature review by Masterjohn - Oct 2021
- COVID winter is coming again in Northern US, Canada, Europe, Russia - Nov 2021
- French recommended 200,000 IU of Vitamin D to stop COVID-19 - Jan 2021
- COVID-19 severity associated with 3 vitamin D genes – Oct 2021
- Vitamin D was the only supplement that fought COVID-19 (out of 6) – Oct 2021
- Colin Powell died of COVID-19 (he had 4 risk factors for low vitamin D) – Oct 18, 2021
- https://vdmeta.com/
- COVID-19 treated by Vitamin D (example: ICU reduced by 5X) – 20th meta-analysis Oct 13, 2021
- COVID-19 and Vitamin D (42 studies, consensus) – Oct 2021
- Vitamin D was a top COVID-19 treatment at 4 hospital groups - May 2021
~ 83,000 patients
- COVID-19 and Vitamin D - Wikipedia Oct 10, 2021
- COVID-19 risk reduction by early treatment: 5X Vitamin D – Oct 8, 2021
- Dr. McCullough on COVID-19: vaccine problems, home treatment – video, slides, transcript – Oct and Dec 2021
- COVID-19 symptoms and comorbidities associated with the type of Vitamin D Receptor – Oct 2021
- COVID-19 and Vitamin D – expert consensus and guidelines (Annweiler, behind paywall) – Oct 2021
- Pfizer vaccine half as effective as Moderna after 6 months (fading or Delta) - Mayo preprint Aug 2021
- Severe COVID-19 2.5 X more likely if low vitamin D (23 studies) – 19th meta-analysis Oct 2021
- COVID-19 cases vs. vaccination (counties and countries) - Sept 2021
- 7 Symptoms predictive of COVID-19 (from 1,000,000 in UK) – Oct 2021
- Emergency treatments if get COVID-19 symptoms - Oct 2021
- COVID-19 mortality extrapolates to zero at 50 ng of vitamin D – 18th Meta-analysis Sept 2021
- COVID-19 patients getting 300,000 IU of Vitamin D were 5X less likely to die – Sept 2021
- COVID-19 patients had low levels of Zinc, Vitamin A, Vitamin D, and Vitamin C – Sept 2021
- US COVID-19 deaths now exceed 1918 flu, soon AIDS (Vitamin D fights all 3) - Sept 19, 2021
- Predict 2X more likely to die of COVID-19 if vitamin D Deficient (Iran 2020) – Sept 2021
- COVID-19 appears reduced by Resveratrol plus 100K IU of vitamin D – Small RCT Sept 2021
- COVID-19 Vitamin D Clinical Trials - US Sept 15, 2021 36 trials
- Long-haul, VAERS, Ivermectin, vaccines, etc. Drs. Seheult, Patrick: Video with table of contents - Sept 17, 2021
- Vitamin D might augment COVID-19 vaccines – 6 papers as of Dec 2021
- COVID-19 risk reduced 4X by each of: Vitamin D, Omega-3, Curcumin, Zinc (each increases D in cells)
- COVID-19 risk reduction by early treatment: 5X Vitamin D – Oct 8, 2021
- Vitamin D and Health video with transcript - Dr. Grant Sept 2021
- Influence of Vitamin D on COVID-19 (Guidebook) - Benskin Sept 2021
- Vitamin D and COVID, review of evidence, loading dose if less than 50 ng - Masterjohn Sept 2021
- Higher vitamin D, less severe COVID and deaths in hospital (in Iran this time) – Sept 2021
- COVID-19 therapeutics and cytokine storms (vitamin D occurs 51 times) – Aug 2021
- Many Vitamin D metabolites: some help skin aging, reduce Cytokine storms, but are not tested – Aug 2021
- Fauci investing 3 billion dollars to develop a safe pill to fight virus (but we already have 3) – Aug 4, 2021
- US coalition of Black and Latino churches hope to reduce the 3X COVID-19 disparity - Aug 2021
- Less than 10 dollars of Vitamin D per COVID-19 life saved in Myanmar - Jan 2021
- Effectiveness of COVID-19 vaccines might be increased by Vitamin D – Aug 2021
- Various forms of Vitamin D should be able to fight COVID-19 (model) – Aug 2021
- Vaccinated and Unvaccinated are just as infectious after catching COVID-Delta (UK study) - Aug 2021
- In-home testing of viral load, etc. Dr. Topol interview with transcript – Aug 11, 2021
- Boosting Immunity with Vitamin D to reduce COVID-19 risks - Aug 2021
- A virus can mutate to avoid a vaccine, need more than vaccines to fight a virus – July 31, 2021
- COVID-19 mortality was associated with vitamin D deficiency of 47 countries – July 2021
- Severe COVID-19 5X more likely if low vitamin D (23 studies) – 16th meta-analysis July 2021
- Initial efficacy of vaccines against COVID-Delta - July 20, 2021
- Taking vitamin D (guess 600 IU avg) reduced US COVID-19 risk by 25 percent (more D would be better) – July 2021
- Many drugs, such as Vitamin D, decrease the risk of COVID-19 – July 2021
- Vaccine effectiveness may drop to only 16% in 6 months if time between jabs was only 3 weeks – July 2021
- Vitamin D known to fight 8 classes of health problems, probably fight COVID-19 as well – July 2021
- Vitamin D, C, A, and E, as well as Iron, Se, and Zinc each augment vaccine response – July 2021
- Vitamin D is one of 14 ways proven to treat COVID-19 – July 2021
- COVID-19 death 40 percent less likely if supplemented with Vitamin D and got above 30 ng (Spain 108,000 people) – July 2021
- Severe pediatric COVID 5.5 more likely if low vitamin D (review of 6 studies) -July 2021
- 5,000 U daily raised Vitamin D a bit and helped COVID-19 a bit – RCT June 2021
- Severe COVID-19 3.5 more likely if low vitamin D (30 studies) – meta-analysis July 2021
- 7X less likely to go to ICU if COVID-19 ward gave calcifediol (semi-activated Vitamin D) – July 2021
- Poor food, little intense exercise again associated with low Vitamin D (and more COVID-19 in this case) – July 2021
- If low vitamin D, 2.5X more likely enter hospital with COVID-19 (UK, 10 months) – June 17, 2021
- COVID-19 patients who had supplemented with Vitamin D were 3X less likely to enter ICU – June 2021
- Vitamin D and COVID-19 both affect immune cells – June 2021
- Pandemics are now every few years, next might be in 2025 (Vitamin D levels have crashed) – June 2021
- Higher rate of serious Vaccination problems than COVID-19 deaths – June 24, 2021
- COVID-19 5X worse if poor Vitamin D gene (CYP2R1) – June 2021
- 600,000 IU of Vitamin D helped 26 out of 28 COVID-19 patients in ICU (Brazil and Bolivia) June 2021
- 3 billion dollars being spent on developing a pill to treat pandemic viruses (ignoring Vitamin D)
- COVID-19 death in hospital 5X more likely if low vs high vitamin D – preprint June 2021
- COVID-19 and variants are here to stay (he fails to mention that vitamin D might help) - June 2021
- Vitamin D reduces COVID-19 complications – June 2021
- How Vitamin D, Magnesium, Omega-3 and Zinc prevent and treat COVID-19 and many other health problems – June 2021
- More than enough evidence on the Yellow Card system to declare the COVID-19 vaccines unsafe for use in humans. - June 9, 2021
- COVID-19 deaths 1.7X more likely if low vitamin D (even after “adjusting” for low D health problems) – May 2021
- Vitamin D has the most supporting science of all micronutrients to fight COVID-19 – May 2021
- COVID-19 fought by Vitamin D, how much more evidence is needed -May 2021
- COVID-21 (COVID-19 with mutations) causing increased pregnancy problems in Brazil and India – May 2021 Pregnancy
- COVID-19, dark skin, pregnancy - Dr. Grimes, etc. - May 2021 Pregnancy
- Increased pregnancy problems with COVID-19 – meta-analysis and letter to editor – April 2021 Pregnancy
- Vitamin D Receptor activation should reduce ARDS associated with COVID-19 - June 2020
- Half of COVID-19 death rate differences explained by rates of elderly influenza vaccination and low vitamin D – April 2021
- COVID-19 inflammation extinguished by 60,000 IU of vitamin D nanoemulsion daily for a week – RCT May 2021
- Treatments for 303,000 COVID-19 patients: vitamin D is both popular and over-the-counter – May 2021 Red = Vitamin D
- Dr. Fauci speculates on future use of masks in the winter (when vitamin D levels are low) May 2021
- Country reliant on tourism vaccinated, but now 1 in 1,000 get COVID-19 daily - May 2021
- Many supplements appear to fight COVID-19 – vitamin D cited 52 times – May 2021
- COVID-19 deaths 1.5X less likely if more than 40 ng of vitamin D – US VA – April 2021
- Growing consensus: COVID-19 symptoms are due to infected blood vessels - April 2021
- COVID-19 while pregnant increased many infant health problems by 1.5X – April 29, 2021 Pregnancy
- Multiple Sclerosis patients had fewer COVID-19 problems (Note: many MSers take Vitamin D) – April 30, 2021
- Problems with vaccine use during a pandemic - Dr. Bossche interview with transcript - April 22, 2021
- Vitamin D supplementation and high levels reduce COVID-19 deaths in elderly – Review April 17, 2021
- Co-Epidemic of Obesity and COVID-19 (a co-epidemic of Vitamin D not mentioned) – April 2021
- Vitamin D fights many health symptoms, including COVID-19: Dr. Mahtani video and transcript - April 2021
- COVID-19 vaccines look good in the short term, but probably not good for the long term
- COVID-19 while pregnant is not good (increased risk of dying by 22X) – April 2021 Pregnancy
- COVID-19 increased chance of death within 6 months by 1.6X, even if not hospitalized – April 2021
- Elderly nutrition and COVID-19 – systematic review July 2021
- Hospitalized children with COVID-19 and inflammation had lower vitamin D – March 2021
- Probablity of COVID-19 death increased 8X if had Periodionttitis
- COVID-19 risks reduced by Vitamin D, Magnesium, Zinc, Resveratrol, Omega-3, etc. (auto-updated)
- Long-haul COVID-19 - another hint that Vitamin D should help - Dec 2020
- 6X less risk of COVID-19 ICU if Vitamin D and Vit B12 and Mg – Jan 2021
- Vitamin D supplementation and high levels reduce COVID-19 deaths in elderly – Review April 17, 2021
- Severe childhood COVID-19 associated with Vitamin D deficiency (hospital in Turkey) – March 2021
- Kidney patients who happened to be getting high-dose Calcitriol were 9X less likely to die of COVID-19 - April 6, 2021
- Overview of reviews of COVID-19 and vitamin D, etc. – April 2021
- Less COVID-19 infection, mortality in countries with higher Vitamin D (Asia in this case) – May 2021
- COVID-19 was the third-leading cause of death in the US, especially in those with dark skins - April 1, 2021
- Children with COVID-19 and low levels of Vitamin D have more severe cases – March 31, 2021
- Risk of COVID-19 death was 4.9 X higher if very low vitamin D – March 31, 2021 17th mortality observation
- Diabetes has many bidirectional links with COVID-19 – March 2021
- Diabetes is one of the 26 health risks identified by the CDC for getting COVID-19 - ALL of which are associated with low vitamin D
- COVID-19 was 2.6X more severe if very low Vitamin D (43 studies) – meta-analysis March 26, 2021
- To protect against COVID-19, how much vitamin D – 20 to 50 ng – March 19, 2021
- COVID-19 mortality for Parkinson’s is 1 in 5, speculates that vitamin D could help - March 18, 2021
- Prefer 40 – 60 ng of Vitamin D to minimize COVID-19 – March 17, 2021
- The lower the Vitamin D, the worse the COVID-19 (600 in Turkey)– March 2021
- COVID-19 prognostic indicators in plasma extrapolate to zero if Vitamin D is 40 to 80 ng – March 2021
- COVID public health messages 1, 2, and 3 should be - vitamin d vitamin d, vitamin d (video and transcript) - Mar 5, 2021
- COVID-19 mortality 2X higher if low Vitamin D (Mexican hospital, preprint) - March 2021
- Chronic Fatigue Syndrome and long-haul COVID-19
- low vitamin D, autoimmune and cytokine storms may be involved on both
- 2.1 X more COVID-19 deaths in European countries with less than 20 ng of vitamin D – March 12, 2021
- Supporting non-standard but proven ways to fight COVID-19 can result in job loss – March 2021
- 3X less likely to die of COVID-19 if good level of vitamin D (seniors in Boston)– March 8, 2021
- Low Vitamin D associated with 2.7X more severe COVID-19 – 12th MA March 5, 2021
- COVID-19 fought by Vitamin D or Heat - Drs Seheult and Patrick video - March 3, 2021
- Vitamin D Deficiency and Covid-19: Book by Drs Anderson and Grimes - July 2020
- Vitamin D recommendations for COVID-19 – Spanish Geriatrics Society – March 2021
- 250,000 FREE bottles of vitamin D to fight COVID-19 by Dr. Murray at iHerb – March 3 2021 Dr. Oz show
- Vitamin D and COVID-19 webinar - Feb 24, 2021
- Mongolia's National Vitamin D3 Program started in 2019
- COVID-19 what it is, prevention by Functional Nutrition doctor - Feb 2021
- All COVID-19 in ICU had low vitamin D, no difference in outcome if low vs very low – Feb 2021
- Low-cost Ivermectin and Vitamin D fight COVID-19 – Marik video 1 hr – Feb 18, 2021
- Low vitamin D associated with COVID-19 problems in NYC hospitals – Feb 2021
- All COVID-19 patients had low vitamin D, the lowest were more likely to die – Feb 18, 2021
- Vitamin D not help 10 days after COVID-19 symptoms - RCT March 2021
- 5X less likely to enter ICU with COVID-19 if get Calcifediol (semi-activated vitamin D) - RCT Feb 19, 2021
- Ultra-Orthodox Jews have concealing clothing, high levels of COVID-19, and ultra low Vitamin D - Feb 2021
- c19study.com/d Summary of Vitamin D and COVID studies (the following is updated automatically)
- Vitamin D can prevent severe COVID-19 in Latin America too – review Feb 1, 2021
- Vitamin D and COVID-19: 1 hour simple video - Jan 31, 2021
- Higher vitamin D in a country is associated with fewer COVID-19 cases (in Asia) Feb 3, 2021 44th association
- Vitamin-D and COVID-19: time for the profession to take a stand – Jan 20, 2021
- Roll Call of Credible Experts Advocating Vitamin D for COVID-19 - Jan 26, 2021
- Call for immediate action - Fight COVID-19 with vitamin D (up to 4,000 IU) - Jan 28, 2021
- Vitamin D, Zinc, etc. look promising for COVID-19 (Holick) – Jan 25, 2021
- Heavy Smokers 2.2 X more likely to be hospitalized with COVID-19 (they typically have 10 ng less Vitamin D) Jan 25 FREE PDF
- Vitamin D plus Inositol might help pregnancies during COVID-19 – April 2021
- MATH plus protocol for COVID-19 includes Calcifediol or Vitamin D - Jan 2021
- Vitamin D supplementation fights COVID-19 – 11th meta-analysis Jan 24, 2021
- Vitamin D helps the immune system fight COVID-19 – video Jan 21, 2021
- COVID-19 2.7 X more likely to be severe if less than 8 ng of vitamin D (China) – Jan 2021
- 2.7 fewer COVID-19 hospital deaths in those having more than 30 ng of vitamin D – Mayo Jan 9, 2021
- Vitamin D Help Us Fight Infections - interview of Dr. Thakkar (transcript) Jan 20, 2021
- COVID-19 onset strongly associated with latitude in Europe (Vitamin D)– Jan 21, 2021
- France: 73 experts and 6 academies recommend vitamin D to prevent COVID-19 Jan 19, 2021
- Worse COVID-19 patients got 400,000 IU of vitamin D, deaths cut in half – Jan 14, 2021
- Vitamin D-COVID interview by Dr. Campbell of Davies (member of UK Parliament) - Jan 17, 2021
- Iranians with COVID-19 were 2.3 X more likely to die if low vitamin D – Jan 2021
- Many COVID-19 risks are associated with low vitamin D (7 studies) – Systematic Review Jan 2021
- 40 ng of Vitamin D to fight COVID 15K to 50K weekly or 100K monthly - Spanish Jan 2021
- Poor COVID-19 prognosis was 6 X more likely if low vitamin D – Jan 21, 2021
- Unraveling the roles of vitamin D status and melanin during COVID-19 (Review) Jan 11
- Less than 10 dollars of Vitamin D per COVID-19 life saved in Myanmar - Jan 2021
- 2.8 X fewer COVID-19 nursing home deaths if add 10,000 IU Vitamin D daily for a week (small observation)- Jan 2021
- 3.7 X less likely to die of COVID-19 if supplemented with Vitamin D - meta-analysis Jan 5, 2021
- COVID-19 test positive 4.5 X more likely if had low vitamin D test within 4 years – Jan 6, 2021
- Don’t Let COVID-19 Patients Die With Vitamin D Deficiency - Jan 5, 2021
- Less likely to test positive for COVID-19 if higher Vitamin D – meta-analysis Jan 6, 2021
- Vitamin D reduces COVID-19 by 80 percent - anonymous meta-analysis - Jan 5, 2021
- COVID 19 Video - Drs. Seheult and Campbell - Jan 2021
- Many drugs increase ACE2 and COVID-19 (176 page review) - Dec 2020
- Italian nursing home COVID-19 – 4X less likely to die if taking Vitamin D– Dec 22, 2020
- Take 50,000 IU of Vitamin D weekly before and after COVID-19 vaccination by VItaminDWiki
- COVID-19 lung infection upsets Vitamin D genes (so more or different form of Vit D is required) - Dec 22, 2020
- COVID-19 Disease and Vitamin D: A Mini-Review – Dec 15, 2020
- French Consensus – 200,000 IU of Vitamin D if get COVID-19 – Dec 22, 2020
- Rational approach to COVID-19: 50k-100k of Vitamin D weekly – Dec 2020
- Shift workers 2X more likely to get COVID-19 (low Vitamin D) - Dec 2020
- COVID-19 plus pneumonia in ICU with low vitamin D equaled Death - Dec 2020
- Excellent on-going analysis of Vitamin D and COVID-19 publications
- Those getting high dose vitamin D were 7 X less likely to die of COVID-19 - Dec 11, 2020
- COVID-19 patients with low vitamin D had far fewer natural killer cells – Dec 2020
- COVID-19 Vitamin D: Overview of Evidence by Dr. Seheult (Video and transcript) - Dec 10, 2020
- 75 articles indicate that Vitamin D should fight COVID-19 – Evidence Review Dec 10, 2020
- COVID-19 Vitamin D: Overview by Dr. in Sri Lanka (Video and transcript) - Dec 8, 2020
- Vitamin D recommended to fight COVID-19 by 2 groups – Dec 7, 2020
- Vitamin D helps athletes while reducing their COVID-19 risk - Dec 4, 2020
- 5X more likely to test positive for COVID-19 if low vitamin D in previous 5 years (900,000 people) - Dec 4, 2020
- 5.8 X more likely to die of COVID-19 if low vitamin D - Systematic Review Dec 3, 2020
- Evidence of Vitamin D fighting COVID-19 etc. - take 4,000 IU if less than 20 ng (UK) – Dec 1, 2020
- 3.8 X higher risk of COVID-19 death if low vitamin D – Belgium Nov 25, 2020
- Hyperglycemic 2X more likely to have severe COVID-19 - Nov 2020 Diabetes
- A Medical School COVID-19 protocol includes Vitamin D for all phases – Marik Nov 2020
- Fight COVID-19 without drugs or vaccines, Vitamin D is the single most-studied way – Nov 2020
- Hospital COVID-19 observation: 7X more likely to live if more than 20 ng of vitamin D– Nov 19, 2020
- Higher vitamin D associated with fewer cases and deaths in India Nov 2020
- COVID-19 defeated 3x faster by 420,000 IU Vitamin D nanoemulsion – RCT Nov 12, 2020
- 9X COVID-19 survival in nursing home if had 80,000 IU dose of vitamin D in previous month – Oct 2020
- Rate of COVID-19 test positive is 40 pcnt lower if high vitamin D (192,000 people) - Holick Sept 2020
Intervention
Intervention Trial Summary Table
Details on #5 = COVIT-TRIAL Dec 27
Note: >70% of the RCT using Vitamin D to fight COVID-19 are using at least 100,000 IU during the first week
Trial Results
- 21 fewer days in hospital with ARDS (COVID) if 10,000 IU of Vitamin D daily after enter hospital – RCT April, 2022
- Speculation: "No hospitalization if had gotten high dose vitamin D at COVID symptom onset"
- 4X less likely to get COVID following 4,000 IU daily for a month – RCT April 2022
- Group achieving 30 ng (vs 26 ng) were 2X less likely to get COVID symptoms - RCT Jan 2022
- 5,000 U daily raised Vitamin D a bit and helped COVID-19 a bit – RCT June 2021
- 5.000 IU daily does not help miuch
- Vitamin D reduced COVID-19 inflammation (60,000 IU daily for 8 days) - RCT Feb 2021
- Vitamin D not help 10 days after COVID-19 symptoms - RCT March 2021
- 5X less likely to enter ICU with COVID-19 if get Calcifediol (semi-activated vitamin D) - RCT Feb 19, 2021
- 2X fewer COVID-19 deaths observed if infrequent vitamin D (2X more deaths if daily dose) – ClinicalTrial Oct 20, 2020
- A Clinical Trial, not a Randomized Controled Clinical Trial
- COVID-19 defeated by calcifediol form of Vitamin D in Spain - pilot RCT Aug 29, 2020
- Severe COVID-19 not fought by vitamin D when given too late - RCT Nov 18, 2020
Virus meta-analyses and Systematic Reviews
Short URL for this section = is.gd/vdwmeta
- Severe COVID 2.6 X less likely if supplement with Vitamin D – 26th meta-analysis - July 2022
- COVID test positive is about half as likely if have Vitamin D – 24th meta-analysis - Jan 2022
- Small amounts of Vitamin D reduce Influenza risk by 22 percent (loading dose is far better) – meta-analysis Jan 2022
- Vitamin D fights COVID (54 studies of 1,400,000 people) – 23rd meta-analysis - Dec 2021
- COVID-19 treated by Vitamin D (reduce ICU by 3X) - 22nd meta-analysis - Dec 29, 2021
- COVID-19 death increased 2X if low Vitamin D (less than 10 to less than 30 ng) – 21st meta-analysis Dec 2021
- COVID-19 risk reduced by vitamin D supplementation – umbrella review of 7 meta-analysis – Oct 2021
- COVID-19 treated by Vitamin D (example: ICU reduced by 5X) – 20th meta-analysis Oct 13, 2021
- Severe COVID-19 2.5 X more likely if low vitamin D (23 studies) – 19th meta-analysis Oct 2021
- COVID-19 mortality extrapolates to zero at 50 ng of vitamin D – 18th Meta-analysis Sept 2021
- COVID-19 death 1.6 X more likely if low vitamin D (24 studies) – 17th meta-analysis Aug 2021
- Severe COVID-19 5X more likely if low vitamin D (23 studies) – 16th meta-analysis July 2021
- Severe COVID-19 3.5 more likely if low vitamin D (30 studies) – meta-analysis July 2021
- COVID-19 patients who had supplemented with Vitamin D were 3X less likely to enter ICU – June 2021
- Low Calcium associated with severe COVID-19 – several studies
- COVID-19 mortality 3X more likely if low vitamin D (999,179 people) – meta-analysis March 29, 2021
- COVID-19 was 2.6X more severe if very low Vitamin D (43 studies) – meta-analysis March 26, 2021
- Low Vitamin D associated with 2.7X more severe COVID-19 – 12th MA March 5, 2021
- Vitamin D supplementation fights COVID-19 – 11th meta-analysis Jan 24, 2021
- 3.7 X less likely to die of COVID-19 if supplemented with Vitamin D - meta-analysis Jan 5, 2021
- Less likely to test positive for COVID-19 if higher Vitamin D – meta-analysis Jan 6, 2021
- Vitamin D reduces COVID-19 by 80 percent - anonymous meta-analysis - Jan 5, 2021
- COVID-19 1.7X more likely to be severe if low Vitamin D - meta-analysis Oct 2020
- Low Vitamin D associated 1.8X increased risk of COVID-19 death in hospital – meta-analysis Nov 4, 2020
- Acute viral respiratory infections (RTI) reduced by Vitamin D - 20 reviews - Aug 2020
- Prudent to consider that Vitamin D has a role in COVID-19 – meta-analysis – Aug 7, 2020
- Risk of enveloped virus infection is increased 50 percent if poor Vitamin D Receptor - meta-analysis Dec 2018
- Hepatitis B patients have 2 ng lower level of Vitamin D – meta-analysis June 2019
- Influenza Vaccination not benefited by lowish levels of vitamin D – meta-analysis March 2018
Reviews
- Vitamin D supplementation reduced risk of COVID-19 ICU by 2.8 X – review of 10 reviews Feb 2022
- COVID-19 and Vitamin D (42 studies, consensus) – Oct 2021
- Overview of reviews of COVID-19 and vitamin D, etc. – April 2021
- Vitamin D can prevent severe COVID-19 in Latin America too – review Feb 1, 2021
- Many COVID-19 risks are associated with low vitamin D (7 studies) – Systematic Review Jan 2021
- Excellent on-going analysis of Vitamin D and COVID-19 publications not a formal publication
- COVID-19 Disease and Vitamin D: A Mini-Review – Dec 15, 2020
- 75 articles indicate that Vitamin D should fight COVID-19 – Evidence Review Dec 10, 2020
- 5.8 X more likely to die of COVID-19 if low vitamin D - Systematic Review Dec 3, 2020
- COVID-19 Scoping Review of Vitamin D finds lots of evidence, protocol to be used is unclear - Nov 26, 2020
Observe - Less likely to become infected
short URL to this section = https://is.gd/COVID_less
- 14 X less likely to have severe COVID if previously had more than 40 ng level of Vitamin D – Feb 2022
- COVID-19 patients had low levels of Zinc, Vitamin A, Vitamin D, and Vitamin C – Sept 2021
- Taking vitamin D (guess 600 IU avg) reduced US COVID-19 risk by 25 percent (more D would be better) – July 2021
- Vitamin D is one of 14 ways proven to treat COVID-19 – July 2021
- COVID-19 death 40 percent less likely if supplemented with Vitamin D and got above 30 ng (Spain 108,000 people) – July 2021
- Children with COVID-19 and low levels of Vitamin D have more severe cases – March 31, 2021
- Kidney patients who happened to be getting high-dose Calcitriol were 9X less likely to die of COVID-19 - April 6, 2021
- 2.1 X more COVID-19 deaths in European countries with less than 20 ng of vitamin D – March 12, 2021
- Mongolia's National Vitamin D3 Program started in 2019
- COVID-19 2.7 X more likely to be severe if less than 8 ng of vitamin D (China) – Jan 2021
- COVID-19 test positive 4.5 X more likely if had low vitamin D test within 4 years – Jan 6, 2021
- 3.8 X higher risk of COVID-19 death if low vitamin D – Belgium Nov 25, 2020
- 5X more likely to test positive for COVID-19 if low vitamin D in previous 5 years (900,000 people) - Dec 4, 2020
- 1 Rate of COVID-19 test positive is 40 pcnt lower if high vitamin D (192,000 people) - Holick Sept 2020
- 2 COVID-19 increased 3.5 X if Ultra-Orthodox (cloth) Sept, 2020
- 3 COVID-19 1.77X less likely if more than 20 ng of vitamin D (489 people) – JAMA Sept 2020
- 1.8 X higher risk if <12 ng vs >30 ng - independent of sex, race
- 4 7X less likely to test COVID-19 positive if had more than 30 ng of Vitamin D (7,804 Israelis) - preprint July 3
- and 20X less likely to be hospitalized for COVID-19
- UV provides the best explanation of COVID-19 variation in Italy (74 pcnt) – Nov 2020
- Vitamin D helps athletes while reducing their COVID-19 risk - Dec 4, 2020
- Vitamin D has eliminated ICU COVID-19 in hospital in Dubai since June - Sept 26, 2020
- 1.4X less risk of COVID-19 if had taken some Vitamin D (a US yes-no survey) – Nov 30, 2020
- COVID-19 defeated 3x faster by 420,000 IU Vitamin D nanoemulsion – RCT Nov 12, 2020
- COVID-19 antibodies 2.6 X more likely if had symptoms and low vitamin D (UK hospital staff)– Oct 5 2020
- Vitamin D Cuts SARS-CoV-2 Infection Rate by Half Mercola Sept 28
- 47% lower SARS-CoV-2 positivity rate if > 50 ng vs < 20 ng
- 58% lower risk of testing positive for SARS-CoV-2 if > 30 ng vs < 30 ng
- 2X higher risk of hospitialization if <30 ng
- ICU patients got semi-activated Vitamin D - death rate dropped to 2% from 50%
Observe - Reduced Severity/Death
MORTALITY AND Virus (automatically updated):
- Elderly who had been in COVID ICU were 4X more likely to die if low vitamin D – Nov 2022
- More COVID mortality if less than 20 ng of Vitamin D (Mexico) – May 2022
- 15,000,000 excess deaths in 2 years - May 2022
- COVID death 5.2X more likely if Vitamin D deficient – May 2022
- 29 X more likely to die of COVID if less than 20 ng of Vitamin D - March 2022
- Giving Vitamin D reduced COVID Mortality– Review of 11 studies – March 2022
- 18 million excess global deaths in past 2 years: COVID plus collateral damage - Lancet March 2022
- COVID severity and death more likely if low vitamin D (Egypt this time) - March 2022
- US nursing homes are epicenters for COVID deaths (200,000) - Feb 2022
- Ivermectin taken before COVID decreased death rate by 68 percent (3,000 with Ivermectin vs 3,000 without) - Dec 24, 2021
- Increase in non-COVID deaths (ages 18-64) in Indiana, India, etc. - Jan 5, 2022
- Only 35,000 died in US of COVID who previously had been healthy
- COVID-19 mortality extrapolates to zero at 50 ng of vitamin D – 18th Meta-analysis Sept 2021
- COVID-19 patients getting 300,000 IU of Vitamin D were 5X less likely to die – Sept 2021
- Predict 2X more likely to die of COVID-19 if vitamin D Deficient (Iran 2020) – Sept 2021
- COVID-19 mortality not associated with Vitamin D (everyone had very low levels) -Sept 2021
- COVID-19 mortality for Blacks is 5X that for whites in 2 LA Hospitals - July 2021
- COVID-19 mortality was associated with vitamin D deficiency of 47 countries – July 2021
- Similar death rate for Vaccination and COVID-19 study and video – June 24, 2021
- COVID-19 death in hospital 5X more likely if low vs high vitamin D – preprint June 2021
- COVID-19 deaths 1.7X more likely if low vitamin D (even after “adjusting” for low D health problems) – May 2021
- COVID-19 deaths 1.5X less likely if more than 40 ng of vitamin D – US VA – April 2021
- Vitamin D supplementation and high levels reduce COVID-19 deaths in elderly – Review April 17, 2021
- Less COVID-19 infection, mortality in countries with higher Vitamin D (Asia in this case) – May 2021
- COVID-19 was the third-leading cause of death in the US, especially in those with dark skins - April 1, 2021
- Risk of COVID-19 death was 4.9 X higher if very low vitamin D – March 31, 2021
- COVID-19 mortality 2X higher if low Vitamin D (Mexican hospital, preprint) - March 2021
- All COVID-19 patients had low vitamin D, the lowest were more likely to die – Feb 18, 2021
- 2.7 fewer COVID-19 hospital deaths in those having more than 30 ng of vitamin D – Mayo Jan 9, 2021
- Worse COVID-19 patients got 400,000 IU of vitamin D, deaths cut in half – Jan 14, 2021
- Iranians with COVID-19 were 2.3 X more likely to die if low vitamin D – Jan 2021
- Poor COVID-19 prognosis was 6 X more likely if low vitamin D – Jan 21, 2021
- Less than 10 dollars of Vitamin D per COVID-19 life saved in Myanmar - Jan 2021
- 2.8 X fewer COVID-19 nursing home deaths if add 10,000 IU Vitamin D daily for a week (small observation)- Jan 2021
- Italian nursing home COVID-19 – 4X less likely to die if taking Vitamin D– Dec 22, 2020
- Shift workers 2X more likely to get COVID-19 (low Vitamin D) - Dec 2020
- Those getting high dose vitamin D were 7 X less likely to die of COVID-19 - Dec 11, 2020
- COVID-19 male mortality increased 3.9 X if low vitamin D – observation Nov 25, 2020
- Hospital COVID-19 observation: 7X more likely to live if more than 20 ng of vitamin D– Nov 19, 2020
- COVID-19 lung death 4X more likely in Iran if less than 25 ng of vitamin D – Oct 30, 2020
- COVID-19 was killing dark-skinned doctors, then they got a Vitamin D recommendation
- 9X COVID-19 survival in nursing home if had 80,000 IU dose of vitamin D in previous month – Oct 2020
- 14.7 X more likely to die of COVID-19 if less than 12 ng of Vitamin D (185 Germans) – Sept 10, 2020
- COVID ARDS deaths 2X more likely if less than 10 ng of Vitamin D – Aug 8, 2020
- COVID-19 mortality rate highest North of 35 degrees latitude (Vitamin D) – April 20, 2020
- COVID-19 more frequent and deadly for those with dark skins (high risk of low vitamin D)
- Vitamin D of 30-40 ng fights COVID, Dr. Grimes on Liverpool Study - March 2022
- Higher vitamin D, less severe COVID and deaths in hospital (in Iran this time) – Sept 2021
- Severe childhood COVID-19 associated with Vitamin D deficiency (hospital in Turkey) – March 2021
- Poor COVID-19 prognosis was 6 X more likely if low vitamin D – Jan 21, 2021
- 2.8 X fewer COVID-19 nursing home deaths if add 10,000 IU Vitamin D daily for a week (small observation)- Jan 2021
- Italian nursing home COVID-19 – 4X less likely to die if taking Vitamin D– Dec 22, 2020
- Higher vitamin D associated with fewer cases and deaths in India Nov 2020
- Chinese COVID-19 study – 80 pct of severe cases had low Vitamin D, all asymptomatic cases had OK Vit D – Oct 13, 2020
- COVID-19 lung death 4X more likely in Iran if less than 25 ng of vitamin D – Oct 30, 2020
- COVID-19 patients who happened to be taking Vitamin D did much better – Oct 27,2020
- 9X COVID-19 survival in nursing home if had 80,000 IU dose of vitamin D in previous month – Oct 2020
- 15 studies indicating that Vitamin D fights COVID-19 - Dr. Grimes Oct 9, 2020
- Children infection by COVID-19 had much lower levels than controls Research Gate, Turkey Oct 2020
- 32X more likely to have severe-critical COVID-19 in Turkish hospital if Vitamin D deficient – Oct 5, 2020
- Admission to COVID-19 ICU 1.7X more likely to have less than 20 ng of vitamin D – Sept 2020
- Vitamin D levels were NOT associated with COVID-19 severity - Sept 2020
- ALL patients had < 20 ng of vitamin D.
- Impact of Vitamin D Deficiency on COVID-19-A Prospective Analysis from the CovILD Registry,
- Hint: need >30 ng to get a benefit doi: 10.3390/nu12092775
- COVID-19 and Vitamin D studies - Dec 2021
- COVID-19 3.2X more likely to be severe if vitamin D deficient (80 patients) – Sept 22, 2020
- 14.7 X more likely to die of COVID-19 if less than 12 ng of Vitamin D (185 Germans) – Sept 10, 2020
- Vitamin D associated with less severe COVID-19 (Iran) - Aug 28, 2020
- Less COVID-19 at high altitude due to more Vitamin D or other possible reasons – July 2020
- Far fewer COVID-19 deaths in the summer (Europe, Canada) Aug 21
- Death rates fell as vitamin D levels typically go up in the summer.
- Many charts. 4 other possible reasons for the drop in death rates
- COVID ARDS deaths 2X more likely if less than 10 ng of Vitamin D – Aug 8, 2020
- Observations that Vitamin D, Zinc, and Selenium separately reduce COVID-19 – Aug 7, 2020
- Vitamin D Supplementation During the COVID-19 Pandemic Mayo Clinic Letter (Online June 6) Aug 5, FREE 2 page PDF
- "In Slovenia, in view of COVID-19 pandemic, medical doctors were urgently advised by leading experts to supplement vitamin D in high-risk and fragile individuals and in COVID-19 patients"
- Russian Hospital observed 5X more likely to have severe COVID-19 if Vitamin D Deficient – Aug 2020
- Vitamin D Sufficiency Reduced Risk for Morbidity and Mortality in COVID-19 Patients - Holick July 14
- No COID19 deaths in a hospital if >41 ng and <80 years old
- [https://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0239799&utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+plosone%2FPLoSONE+%28PLOS+ONE+-+New+Articles%29|Peer reviewed publication] Sept 25
- "We did observe that 6.3% of the patients who had a blood level of 25(OH)D of at least 40 ng/mL succumbed to the infection compared to 9.7% and 20% who died and had a circulating blood level above and below 30 ng/mL respectively. Thus, a blood level of at least 40 ng/mL may be optimal for vitamin D’s immunomodulatory effect. "
- [https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0239799.s001&type=supplementary|Nice 4 minute video by Dr. Holick] - unfortunately only recommends 1500 - 2000 IU for adults, which will take >6 months to get most people above 16 ng
- Evaluation of the Relationship Between Zinc Vitamin D and b12 Levels in the Covid-19 Positive Pregnant Women posted May 29
- Exclusion Criteria: No vitamin D , Vitamin B12 or Zinc supplement use
- Clinical trial Arm1: Observe COVID-19 Deaths and Vitamin D levels in the UK trial completion June 2021
- Arm2: Measure Vitamin D of patients in general practices and see if they get COVID-19 in the next 6 months (prevention)
- Clinical trial observing Vitamin D levels of 500 people in Spain at entry into ICU and recording outcomes hould have been completed July 2020
- Clinical trial to observe vitamin D levels of 100 COVID-19 Turks in hospital should have been completed July 2020
- Bursa City Hospital, NCT04394390
- WHO 3 RCT for Vitamin D and COVID-19 as of May 27 (WHO not responding when asked for details)
- NCT04386044 Investigating the Role of Vitamin D in the Morbidity of COVID-19 Patients 10/05/2020
- NCT04334005 Vitamin D on Prevention and Treatment of COVID-19 29/03/2020
- ChiCTR2000029732 Impact of vitamin D deficiency on prognosis of patients with novel coronavirus pneumonia (COVID-19) 2020-02-10
- Clinical trial to measure Vitamin D status AND vitamin D genes of COVID-19 patients in Portugal Study completion date March 2021
- No intervention, hope they consider genes not noticed by Vit. D tests: such as Vitamin D Receptor, CYP27B1
Vitamin D Dosing Recommendations for COVID-19
- FLCCC COVID guidelines now include vitamin D loading doses - Jan 2022
- Vitamin D and COVID, review of evidence, loading dose if less than 50 ng - Masterjohn Sept 2021
- To protect against COVID-19, how much vitamin D – 20 to 50 ng – March 19, 2021
- Prefer 40 – 60 ng of Vitamin D to minimize COVID-19 – March 17, 2021
- Vitamin D recommendations for COVID-19 – Spanish Geriatrics Society – March 2021
- French recommended 200,000 IU of Vitamin D to stop COVID-19 - Jan 2021
- Roll Call of Credible Experts Advocating Vitamin D for COVID-19 - Jan 26, 2021
- Call for immediate action - Fight COVID-19 with vitamin D (up to 4,000 IU) - Jan 28, 2021
- Vitamin D, Zinc, etc. look promising for COVID-19 (Holick) – Jan 25, 2021
- Vitamin-D and COVID-19: time for the profession to take a stand – Jan 20, 2021
- MATH plus protocol for COVID-19 includes Calcifediol or Vitamin D - Jan 2021
- France: 73 experts and 6 academies recommend vitamin D to prevent COVID-19 Jan 19,2021
- 40 ng of Vitamin D to fight COVID 15K to 50K weekly or 100K monthly - Spanish Jan 2021
- UK Parliament discussing Vitamin D for COVID-19 Jan 14, 2021. mentioned 66 times - mainly 400 IU
- Take 50,000 IU of Vitamin D weekly before and after COVID-19 vaccination by VItaminDWiki
- French Consensus – 200,000 IU of Vitamin D if get COVID-19 – Dec 22, 2020
- Rational approach to COVID-19: 50k-100k of Vitamin D weekly – Dec 2020
- Vitamin D recommended to fight COVID-19 by 2 groups – Dec 7, 2020
- COVID-19 protocol proposed in India includes Vitamin D - Nov 12, 2020
- Covid-19 protocol includes Vitamin D and aspirin - Nov 27, 2020
- A Medical School COVID-19 protocol includes Vitamin D for all phases – Marik Nov 2020
- Evidence of Vitamin D fighting COVID-19 etc. - take 4,000 IU if less than 20 ng (UK) – Dec 1, 2020
- Clinical trials are proving that Vitamin D fights COVID-19 in hospitals by VitaminDWiki
- Single dose of 200,000 IU
- Vitamin D should fight COVID-19 (but Irish Consortium recommends only 1,000 IU) – Nov 21, 2020
- 600,000 IU initially followed by 10,000 IU daily for 20 days Dr. Coimbra June 15, 2020
- French National Academy recommended 100,000 IU of Vitamin D to elderly to fight COVID-19 - May 2020
- COVID-19 probably fought by 40 ng of Vitamin D - quickly achieved with 200K-400K IU - Oct 28, 2020
- A single dose of 300,000 IU of vitamin D should fight COVID-19 for 2 months - Hypothesis - Aug 21, 2020
- Vitamin D recommended for COVID-19 – yet another study – July 17, 2020
- Massive Review of papers on Vitamin D and COVID-19 - July 3, 2020
- Portion of image from June 5 video (below)
- Parkinson's Disease patients who were taking Vitamin D were 0.56 X less likely to catch COVID-19 - June 2020
- COVID‐19 in Parkinson’s Disease Patients Living in Lombardy, Italy: https://doi.org/10.1002/mds.28176
- Commentary: Myths and facts on vitamin D amidst the COVID-19 pandemic Metabolism, June 2, FREE PDF, peer-reviewed publication
- "Preventive doses of vitamin D3 of 10,000 IU/day for 4 weeks followed by 5000 IU/day to reach a target 25(OH)D level of 100–150 nmol/L [24], and treatment doses >6000 IU/day in deficient individuals to reach a similar level and reduce disease progression [48], are suggested. ""
- Comment: Strange that the treatment dose is less than the prevention dose. Note treatment dose will take > 3 months to help
- Perhaps they meant the treatment dose to be 60,000 IU, not 6,000 IU
- Perspective: improving vitamin D status in the management of COVID-19 May 22 free PDF
- If low: 50,000 IU twice a week at the diagnosis (100,000 IU total)., then 50,000 IU taken once a week for the 2nd and 3rd weeks.
- Note: VitaminDWiki believes that this dosing is not large enough for prevention, much less treatment
- If low: 50,000 IU twice a week at the diagnosis (100,000 IU total)., then 50,000 IU taken once a week for the 2nd and 3rd weeks.
- COVID-19 might be prevented in 2 months by 50,000 IU weekly – May 12, 2020
- for people who have not been taking any vitamin D BusinessWorld May 22 - by Dr Renu Mahtani in videos below
- Vitamin D 60k IU twice a week for two weeks to be followed by 60k once a week for the next six weeks.
- or Vitamin D 60k IU daily for three days to be followed by 60k weekly for the total period of two months.
- Thus 480,000 IU total, No Vitamin D testing needed
Some people wanted improved immune systems, so took more vitamin D
- 2X to 10 X reduction in rate of preemies during COVID-19 in some countries NYT July 19
- No mention about any possible increased Vitamin D sales in Denmark, Ireland, Calgary,
- Sales of vitamin D supplements up 3000% after Public Health England recommendation May 14
- BBC reported a 6X decrease in % people dying of COVID-19 BBC June 16
- "Wonder if increased D ==> fewer % of COVID-19 patients ended up dying: 6% ==> 1%. Noted also in Italy
- Alternately, the decreased death rate of COVID-19 patients might be just due to more Vitamin D in the summer
- 3.7X decrease in Very Low Weight Births (following huge increase in Vitamin D sales) - June 2020 Vitamin D sales had increased by 2500%
- I expect to find many other observations of:
- Fear of COVID-19 ==> Want to improve immune system ==> Take Vitamin D ==> Improved health
- Candidate health concerns for which people have probably have heard about Vitamin D include:
- Pregnancy, Asthma, Multiple Sclerosis, Parkinson's, and Cancer
- I expect to find many other observations of:
COVID-19 associated with Low Vitamin D
- COVID-19 mortality was associated with vitamin D deficiency of 47 countries – July 2021
- Many drugs, such as Vitamin D, decrease the risk of COVID-19 – July 2021
- The lower the Vitamin D, the worse the COVID-19 (600 in Turkey)– March 2021
- COVID-19 prognostic indicators in plasma extrapolate to zero if Vitamin D is 40 to 80 ng – March 2021
- 3X less likely to die of COVID-19 if good level of vitamin D (seniors in Boston)– March 8, 2021
- All COVID-19 in ICU had low vitamin D, no difference in outcome if low vs very low – Feb 2021
- Low vitamin D associated with COVID-19 problems in NYC hospitals – Feb 2021
- Ultra-Orthodox Jews have concealing clothing, high levels of COVID-19, and ultra low Vitamin D - Feb 2021
- Higher vitamin D in a country is associated with fewer COVID-19 cases (in Asia) Feb 3, 2021 44th association
- Heavy Smokers 2.2 X more likely to be hospitalized with COVID-19 (they typically have 10 ng less Vitamin D Jan 30 FREE PDF
- COVID-19 onset strongly associated with latitude in Europe (Vitamin D)– Jan 21, 2021
- Many drugs increase ACE2 and COVID-19 (176 page review) - Dec 2020
- COVID-19 lung infection upsets Vitamin D genes (so more or different form of Vit D is required) - Dec 22, 2020
- Shift workers 2X more likely to get COVID-19 (low Vitamin D) - Dec 2020
- COVID-19 plus pneumonia in ICU with low vitamin D equaled Death - Dec 2020
- COVID-19 patients with low vitamin D had far fewer natural killer cells – Dec 2020
- Excessive insulin decreases vitamin D in 4 ways – problems for diabetic COVID-19 – Dec 2020
- UV provides the best explanation of COVID-19 variation in Italy (74 pcnt) – Nov 2020
- Vitamin D fighting COVID-19 meets all Bradford Hill Criteria - Nov 2020
- Magnesium (which increases vitamin D) may fight COVID-19 - Oct 2020
- COVID-19 and Vitamin D studies - Dec 2021
- Low serum 25‐hydroxyvitamin D levels in patients hospitalised with COVID‐19 are associated with greater disease severity July 3 FREE PDF
- Has undergone peer review, 200,000 IU Vitamin D occasional dosing, 134 people
- Obesity, walking pace and risk of severe COVID-19: Analysis of UK Biobank preprint July 11
- normal weight slow walkers were 2.5 more likely to get COVID-19
- Perspective: Vitamin D deficiency and COVID-19 severity - plausibly linked by latitude, ethnicity, impacts on cytokines, ACE2, and thrombosis (R1) July 2020, FREE PDF
- ICU was 2X less likely for COVID-19 hospitalization if Vitamin D more than 20 ng – July 2020
- T1 Diabetic children with low vitamin D have COVID-19 problems (like diabetic adults) - preprint May 15
- COVID-19 deaths strongly correlated with percent having less than 10 ng of Vitamin D in a country– July 1 2020
- Pregnant women admitted to hospital with COVID-19 5X more often than non-pregnant women NYT June 24
- 31% vs 6%. Note: NYT article is confusing. Note: Vitamin D levels drop during pregnancy
- The role of vitamin D in reducing risk of COVID-19: a brief survey of the literature - June 9, 2020 in VitaminDWiki
- Evidence Supports a Causal Model for Vitamin D in COVID-19 Outcomes – June 3, 2020 in VitaminDWiki
- Founder of VitaminDWiki believes that Causal Modeling will replace many RCTs in the future
- BIG DATA is far faster and lower cost than RCTs while being able to consider far more interactions
- Model A: 16 predictions match observed data; 3 predictions cannot be determined.
- Founder of VitaminDWiki believes that Causal Modeling will replace many RCTs in the future
- Obese have major problems with COVID-19 - probably due to lower vitamin D and higher ACE2 June 5, 2020
- Researchers show potential link between vitamin D and coronavirus NBC News Madison Wisconsin May 22
- Reporting on the study from the University in that city - which is below
- Vitamin D for Covid-19? May 12 FREE PDF
- Perspective: improving vitamin D status in the management of COVID-19 European Journal of Clinical Nutrition May 12 FREE PDF
- Avoidance of vitamin D deficiency to slow the COVID-19 pandemic Martin Kohlmeier, BMJ, May 20 FREE PDF
- Vitamin D deficiency as risk factor for severe COVID-19: a convergence of two pandemics preprint May 5. updated May 18
- 186 patients. Lower Vitamin D levels associated with worse COVID-19 only for males
- Vitamin D levels : all males at same hospital in 2019, males in 2020 with COVID-19
- COVID-19 and vitamin D—Is there a link and an opportunity for intervention? Hrvoje Jakova, letter to the editor, May 1, FREE PDF
- [https://www.researchsquare.com/article/rs-30390/v1 |No COVID-19 patient in ICU had >20 ng, 4 had 12.5-20 ng, 13 had < 12.ng ] preprint May 22
- COVID-19 associated with low Vitamin D in more than 20 studies – May 21, 2020 BMJ reply
- Max Minute: How Much Does Vitamin D Help Against COVID-19? CBS News NYC Video May 19
- The Essential Role of Vitamin D in the Biosynthesis of Endogenous Antimicrobial Peptides May Explain Why Deficiency Increases Mortality Risk in COVID-19 Infections preprint May 16 (at least 10,000 IU daily)
- Vitamin D appears to play role in COVID-19 mortality rates Northwestern Univ. May 7
- "Patients with severe deficiency are twice as likely to experience severe complications, including death"
- "...statistical analysis of data from hospitals and clinics across China, France, Germany, Italy, Iran, South Korea, Spain, Switzerland, the United Kingdom (UK) and the United States."
- There are 2 concurrent pandemics – COVID-19 and Vitamin D deficiency – May 13, 2020
- Vitamin D Deficiency and ARDS after SARS-CoV-2 Infection Irish Medical Journal May 11
- Analysis of 36 COVID-19 patients: Vitamin D status: (nmol) ARDS 27, pneumonia 41;
- and, if <30 nmol. 3.2 X more likely to have intubation
Vitamin D levels are lower in those who test positive for COVID-19 -[doi:10.3390/nu12051359| Nutrients] May 09
- [https://articles.mercola.com/sites/articles/archive/2020/05/08/vitamin-d-level-correlated-to-covid19-outcomes.aspx?cid_source=dnl&cid_medium=email&cid_content=art1HL&cid=20200508Z1&et_cid=DM527863&et_rid=867359477 |Vitamin D Level Is Directly Correlated to COVID-19 Outcome] Mercola May 8
- Overview of many studies and video by Ivor Cummins
- [https://www.sciencedaily.com/releases/2020/05/200507131012.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine%2Fvitamin_d+%28Vitamin+D+News+--+ScienceDaily%29 |Vitamin D linked to low virus death rate in 20 countries in Europe] Science Daily May 7
- [https://doi.org/10.1101/2020.05.01.20087965 |Evidence Supports a Causal Model for Vitamin D in COVID-19 Outcomes] May 6 preprint
- Excellent extensive use of Causal Influence AI to discover associations.
- I have suspected that Causal Influence could be much better, far lower cost, and faster than the use of RCTs
- [https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3586555|Evidence of Protective Role of Ultraviolet-B (UVB) Radiation in Reducing COVID-19 deaths] preprint May 7
- "permanent unit increase in UVI is associated with a 2.2 % decline in daily growth rates of cumulative COVID-19 deaths [p < 0.01]
- as well as a 1.9 % decline in the daily growth rates of CFR [p < 0.05]
- 64 countries, 78 days, 6 UVI models
- [https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3593258#.XrE0oF1wSjU.twitter |Vitamin D Level of Mild and Severe Elderly Cases of COVID-19: A Preliminary Report] May 5
- 176 seniors in S. Asia - published in India
- Almost everyone with COVID-19 in a Louisiana ICU had low vitamin D – April 29, 2020
- COVID-19 mortality rate highest North of 35 degrees latitude (Vitamin D) – April 20, 2020
- COVID-19 was 19X more likely if low vitamin D (may be invalid data)– April 2020 Philippines
- The raw data has strange gaps in the vitamin D levels
- Research Suggests a Link Between Vitamin D Deficiency and COVID-19 Deaths May 5
- Indonesia preprint 13X if vitamin D insufficient,19X for patients who are vitamin D deficient.
- VitaminDWiki has requested but has not yet access to the raw data
- COVID-19 infections associated with very low vitamin D – Turin Italy – March 2020
Speculation
- Vitamin D known to fight 8 classes of health problems, probably fight COVID-19 as well – July 2021
- COVID-19 mortality for Parkinson’s is 1 in 5, speculates that vitamin D could help - March 28, 2021
- COVID-19 what it is, prevention by Functional Nutrition doctor - Feb 2021
- Vitamin D plus Inositol might help pregnancies during COVID-19 – April 2021
- Unraveling the roles of vitamin D status and melanin during COVID-19 (Review) Jan 11
- Don’t Let COVID-19 Patients Die With Vitamin D Deficiency - Jan 5, 2021
- Vitamin D helps athletes while reducing their COVID-19 risk - Dec 4, 2020
- COVID-19 and Vitamin D: Health Authorities do not understand risk-reward – Nov 2020
- COVID-19 – Putative Roles of Vitamin D – Nov 2020
- Fight COVID-19 without drugs or vaccines, Vitamin D is the single most-studied way – Nov 2020
- Vitamin D and Covid-19 (June evidence) – Nov 2020
- COVID-19 deaths are proportional to previous interleukin-6 levels, Vitamin D lowers them – Nov 2020
- Vitamin D3 as Potential Treatment Adjuncts for COVID-19 Nutrients Nov 14
- Evidence Regarding Vitamin D and Risk of COVID-19 and its Severity - Oct 27, 2020
- COVID-19 fought by Vitamin D in 43 studies - Oct 15, 2020
- AI is examining 170,000 potential COVID-19 treatments, Vitamin D is one of only 6 found – Sept 4, 2020
- The benefits of Vitamin D in the COVID-19 pandemic: biochemical and immunological mechanisms Oct 8, behind paywall
- Vitamin D could knock out COVID-19 in 3 months – Dr. Matthews interview Oct 2020
- COVID-19 and Vitamin D studies - Dec 2021
- Possible role of vitamin D supplementation in coronavirus disease 2019 - Sept 2020
- Note how long standard publication takes - it was accepted (after peer review?) June 18
- WHO – Severe COVID-19 mortality reduced by hormones (should consider hormone D too) - Sept 2020
- COVID-19 Call to Action – eliminate Vitamin D deficiency – Manson Sept 1, 2020
- Vitamin D in Prevention and Treatment of COVID-19 (16 reasons) – Sept 1, 2020
- AARP features a news item on Vitamin D (and Zinc) and COVID-19 AARP Aug 17
- Nothing new, but it is nice to see Vitamin D being highlighted
- Perhaps the Vitamin D deficiency pandemic caused the COVID-19 pandemic - Aug 17, 2020
- The Covid-19 pandemic is a Vitamin D Deficiency problem and is easy to solve – June 2020
- Mainstream Media Catching on to Vitamin D’s Impact on COVID - Aug 17, 2020
- Progesterone and ACE2 are possible reasons for fewer female COVID-19 deaths
- MECHANISMS IN ENDOCRINOLOGY: Vitamin D and COVID-19 in European Journal of Endocrinology Aug 1
- 32 pages, 180 references, FREE PDF
__
- Vitamin D3 and K2 and their potential contribution to reducing the COVID-19 mortality rate Inter. J. of Infectious Diseases, Aug 5, FREE PDF
- Has a Causal Loop Diagram of Vitamin D3, K2 and the immune system
- Call to Action: Eliminate Vitamin D Deficiency during COVID-19 (7 reasons) – Manson July 23, 2020 in VitaminDWiki
- Vitamin D and Inflammation: Potential Implications for Severity of Covid-19 May 7, PMID: 32603576
- Vitamin D Supplementation: A Potential Approach for Coronavirus/COVID-19 Therapeutics?
- June 23, 2020 FREE PDF, Peer reviewed by Dr. Grant. Includes the following:
- "We demonstrated that a daily oral supplement of 4000 IU of vitamin D during 10 days represented an adequate dose to enhance dengue virus control and reduce the cytokine response, in vitro, suggesting that vitamin D status can, in fact, restrict the viral assault (53, 54)."
- See also VitaminDWiki: Dengue virus prevented by a small amount of Vitamin D – RCT Nov 2019
- Experts criticise UK govt. for review of Vitamin D COVID-19 Nutragredients July 2
- "Shouldn't the best available proof be enough when it is better than doing nothing?"
- Nursing homes could reduce risk of COVID-19 with Vitamin D – June 30, 2020
- Hill's Criteria indicates that COVID-19 will be treated by Vitamin D - Annweiler June 8 2020
- Evidence that vitamin D is causally linked to COVID-19 outcomes using
- Vitamin D: A cheap yet effective bullet against coronavirus disease-19 – Are we convinced yet?
- June 5, FREE PDF
- How We can fix this pandemic in a month (Vitamin D: 20K IU for 14 days) – June 22, 2020 in VitaminDWiki
- COVID-19 1.9X more likely if Hypocalcemia (which is associated with low vitamin D) June 22, small study, FREE 17 page PDF
- Possible Role of Vitamin D in Covid-19 Infection in Pediatric Population Endocrinol Investigation June 15, FREE PDF
- Covid-19: Public health agencies review whether vitamin D supplements could reduce risk BMJ June 19
- The 2017 BMJ publication that concluded that vitamin D reduced the risk of ARDS was viewed 300,000 times since COVID-19 started.
- An RCT this Winter may be run by the UK to confirm the possibility
- Note: Many other RCTs are already underway - see the top of this section
- Vitamin D and Coronavirus Geriatric Nursing, June 18
- Vitamin D deficiency and co-morbidities in COVID-19 patients – A fatal relationship – June 7, 2020 in VitaminDWiki*
- Does Vitamin D play a role in the management of Covid-19 in Brazil? April 2020 free PDF
- A strong role, but recommends against high doses such as 10,000 IU - no reason given
- Exploring the Links Between Coronavirus and Vitamin D NYT June 10
- A review of preprints, which does not look at on-line comments about about errors in a few of them.
- Apparently authored by a reporter, not a scientist
- Is Vitamin D One of the Key Elements in COVID-19 Days? June 2020, letter to editor, Turkey
- " Although there is a need for more research related to this subject, we think that supplementing vitamin D as a part of standard nutrition may be somewhat effective in providing clinical benefit"
- El rol de la vitamina D en la infección por SARS-CoV-2 Spanish June FREE PDF
- Is Vitamin D One of the Key Elements in COVID-19 Days? Letter to the editor of The journal of nutrition, health & aging - June 13
- YES, 20 references
- Vitamin D Levels and COVID-19 Susceptibility: Is there any Correlation? June 2 FREE PDF
- 4,000 IU for 2 months should help a lot. No data (yet) to support quickly fighting COVID-19 with loading doses
- Does Vitamin D play a role in the management of Covid-19 in Brazil? June 1, FREE PDF
- Recommends AGAINST 10,000 IU/day
- Supplementing with high doses of vitamin D could represent a promising alternative to prevent or treat COVID-19 infection June 1, peer reviewed ,FREE Spanish PDF
- 10,000 IU daily, 50,000 to 100,000 IU weekly
- Your Vitamin D Level Must Reach 60ng/mL Before the Second Wave Mercola June 1
- Founder of VitaminDWiki believes than 40 ng should be sufficient - based on ~40 studes
- Does vitamin D (and C) help with Covid-19 - May 2020 Germany
- Vitamin D deficiency and COVID-19 pandemic May 29 FREE PDF
- Patrick Zemb a Peter Bergmanb Carlos A.Camargo Jr c, Etienne Cavalier d, Catherine Cormier e, Marie Courbebaisse f, Bruce Hollis g, Salvatore Minisola h Stefan Pilz i, Pawel Pludowsk j, François Schmitt k, Mihnea Zdrenghea l, Jean-ClaudeSouberbielle m"
- Premorbid IL-6 levels may predict mortality from COVID-19 preprint, Morry Silberstein May 29 FREE PDF
- Vitamin D: A simpler alternative to tocilizumab for trial in COVID-19? Medical Hypotheses, Morry Silberstein July 2020 FREE PDF
- "Vitamin D lowers immune cell production of IL-6"
- "Vitamin D lowers immune cell production of IL-6"
- Does COVID-19 have a fear of hights? -(or just a fear of the increased VItamin D generated at high altitudes) WP May 31
- Cusco Peru (11,000 feet) - Vitamin D is not mentioned. yet there may be 50% more UVB-generated Vitamin D at that altiude
- "In one peer-reviewed study, published in the journal Respiratory Physiology & Neurobiology, researchers from Australia, Bolivia, Canada and Switzerland looking at epidemiological data from Bolivia, Ecuador and Tibet found populations living above 3,000 meters (9,842 feet) reported significantly lower levels of confirmed infections than their lowland counterparts"
- Reduced COVID-19 in Mexico is associated with higher UV or higher elevation (both of which are associated with higher vitamin D) preprint May 27
- Vitamin-D and COVID-19: Do Deficient Risk a Poorer Outcome? Lancet May 20
- Reviews many reports and includes the following comment by a researcher of "COVIDENCE UK, a study to investigate how diet and lifestyle factors might influence transmission of SARS-CoV-2, severity of COVID-19 symptoms, speed of recovery, and any long-term effect"
- "Despite his enthusiasm for the study, Martineau is pragmatic: “At best vitamin D deficiency will only be one of many factors involved in determining outcome of COVID-19, but it’s a problem that could be corrected safely and cheaply; there is no downside to speak of, and good reason to think there might be a benefit”.
- Should be cost-effective to use Vitamin D, Vitamin C and Curcumin to fight Covid-19 in India preprint May 22
- Fails to mention dose sizes or frequencies
- U.S. Rep. Glenn Grothman (Wisc.) wants the CDC to investigate if Vitamin D can fight COVID-19 May 22
- Letter: does vitamin D have a potential role against COVID-19 May 20
- Optimisation of Vitamin D Status for Enhanced Immuno-protection Against Covid-19 Irish Medical Journal, April 2020
- Lungs as target of COVID-19 infection: Protective common molecular mechanisms of vitamin D and melatonin as a new potential synergistic treatment Aug 2020
- both should help fight lung problems. Clinical Trials needed to see to discover dosing and benefits FREE PDF
- Mechanism of inflammatory response in associated comorbidities in COVID-19 PubMed literature Review May 12, free PDF
- "Vitamin D is highlighted as a potential therapeutic target, because in addition to acting on the immune system, it plays an important role in the control of cardiometabolic diseases"
- Vitamin D: A Low-Hanging Fruit in COVID-19? Medscape May 17
- Statements by a dozen doctors, such as Dr. Rosen: "I've been a huge skeptic from the get-go, and loudly criticized the data for doing nothing. I am surprised at myself for saying there might be some effect,"
- DOES VITAMIN D DEFICIENCY REALLY INCREASE RISK OF DEATH FROM COVID-19? Newsweek May 15
- Reviews about 10% of the items on this page
- Which fights COVID-19 more in the long-term - Vitamin D or Ultraviolet light Elemental+ May 13
- Note: Megadoses of Vitamin D can restore the immune system in days, whereas UV takes months
- Vitamin D and SARS-CoV-2 virus (Vitamin D should help) British Medical Journal May 13, 2020
- Unfortunately. the UK consensus is that 400 IU is enough to prevent or treat any health problem, including COVID-19
- The Possible Role of Vitamin D in Suppressing Cytokine Storm and Associated Mortality in COVID-19 Patients preprint April 30
- FoxNews May 7: China, France, Germany, Italy, Iran, South Korea, Spain, Switzerland, the UK and the US.
- Also reported on in Science Blogs and as The Vitamin That Reduces COVID Risk PSYBLOG May 30
- "Backman said this correlation might help explain the many mysteries surrounding COVID-19, such as why children are less likely to die. Children do not yet have a fully developed acquired immune system, which is the immune system’s second line of defense and more likely to overreact. Children primarily rely on their innate immune system,” Backman said. “This may explain why their mortality rate is lower.”
- "Not only does vitamin D enhance our innate immune systems, it also prevents our immune systems from becoming dangerously overactive"
- Role of vitamin D in pathogenesis and severity of COVID-19 infection preprint April 20
- Includes ACE2 discussion
- Perhaps solve the other pandemic: Vitamin D deficiency — to help beat Coronavirus? April 9, Joanneova - Australia 258 comments 10 days later
- Vitamin D reduces viral respiratory infections – editorial April 18, 2020 in VitaminDWiki
- Taiwan seniors have high vitamin D levels, perhaps that reduces the risk of COVID-19 outbreaks von Helden April 18
- Does Vitamin D Protect Us From Viral Infections? April 6
- Croatian, 17 references - probably does protect
- Deficient Vitamin D status might be a severe risk factor for COVID-19 DailyKos April 9
- The role of Vitamin D in the prevention of Coronavirus Disease 2019 infection and mortality April 8
- Charts of country levels of vitamin D and COIVD-19 cases and mortality Published May 6
- Chart by von Helden No high death rates if Vitamin D> 30 ng / ml. (Mortality> 0.1 dead / 1000 inhabitants)
- COVID-19: Vitamin D deficiency; and, death rates; are both disproportionately higher in elderly Italians, Spanish, Swedish Somali, and African Americans? April 7
- Vitamin D may be a COVID-19 Game-changer - BMJ April 6, 2020
- Vitamins C and D being considered as Coronavirus Treatments - April 7, 2020
- Preventing a COVID-19 pandemic with Vitamin D – Grant April 2020)
- COVID-19 and Vitamin D: Could We Be Missing Something Simple? Children's Health Defence April 9
- COVID-19 prompts awareness of deficiencies of Vitamin D, C and Magnesium - April 6 2020
- Vitamin D Supplements Could Reduce Risk of Influenza and COVID-19 Infection and Death - April 9, 2020
- Vitamin D should prevent COVID-19 (recommended dose takes 3 months to raise levels) - April 2020
- 97 year old woman with hypertension, diabetes, heart problems but with 75 ng of Vitamin D survived COViD-19 von Helden April 10
- Vitamin D supplementation could prevent and treat influenza, CORONAVIRUS, and pneumonia infections - March 2020
VIDEOS and PODCASTS
- Vitamin D and Health video with transcript - Dr. Grant Sept 2021
- Vitamin D fights many health symptoms, including COVID-19: Dr. Mahtani video and transcript - April 2021
- COVID public health messages 1, 2, and 3 should be - vitamin d vitamin d, vitamin d (video and transcript) - Mar 5, 2021
- COVID-19 fought by Vitamin D or Heat - Drs Seheult and Patrick video - March 3, 2021
- Vitamin D and COVID-19 webinar - Feb 24, 2021
- Low-cost Ivermectin and Vitamin D fight COVID-19 – Marik video 1 hr – Feb 18, 2021
- Vitamin D and COVID-19: 1 hour simple video - Jan 31, 2021
- Vitamin D helps the immune system fight COVID-19 – video Jan 21, 2021
- Vitamin D Help Us Fight Infections - interview of Dr. Thakkar (transcript) Jan 20, 2021
- Vitamin D-COVID interview by Dr. Campbell of Davies (member of UK Parliament) - Jan 17, 2021
- Dr. Mark Gordon Recommends for immune system/COVID-19 Jan 6, 15 minutes
- 120,000 IU Vitamin D in a week + Quercetin + Zinc etc. Joe Rogan show
- This is one of 35 videos on Vitamin D and COVID-19 posted in the past week (in 6 languages)
- COVID 19 Video - Drs. Seheult and Campbell - Jan 2021
- If You Get COVID 19: Optimize Immune System (Vitamin D, Monoclonal Antibodies, NAC, Quercetin etc.) Jan 2 Dr. Seheult
- COVID-19 Vitamin D: Overview of Evidence by Dr. Seheult (Video and transcript) - Dec 10, 2020
- COVID-19 and Vitamin D Dec 9, 2020 23 minutes, GERMAN, with captions in any language
- COVID-19 Vitamin D: Overview by Dr. in Sri Lanka (Video and transcript) - Dec 8, 2020
- Vitamin D and COVID-19: Video and PDF by Dr. Grant (includes recommendations)- Nov 25, 2020
- Video review by Dr. Campbell of Observation in India
- Vitamin D and COVID-19 - observational studies found it helps, never hurts - Campbell Oct 31, 2020
- Can vitamin D fight COVID-19 - interview of Dr. Matthews Oct 2020 with transcript
- UK parliament members starting to be interested in Vitamin D for COVID-19 – Oct 10, 2020 with transcript
- COVID-19 and Vitamin D – 3 minute video - Sept 2020 made by students at low cost, but with high content
- Interview of A Marteneau Aug 2, 2020 36 minutes
- 10X more needed for prevention trial as treatment trial, 400 IU might be useful in the UK
- Chris Masterjohn 33 minute Vitamin D and COVID-19 literature review Aug 14, 2020
- " > 30 ng "in some way, shape, or form is associated with lower COVID-19 risk"
- Vitamin D looks very promising - Dr. Cambell July 27, 2020 37 minutes
- High Fructose reduces Vitamin D needed to fight COVID-19 June 12, 2020 video, reviews many studies
- COMING OUT STRONGER FROM LOCKDOWN WITH VITAMIN D: A VITAMIN D MOVEMENT INITIATIVE Renu Mahtani and 3 others 13 minutes, June 5, 2020 - see her other video below.
- "It is not an optional supplement, It is a non negotiable cellular necessity" 40 ng minimum
- "Worrying about Vitamin D toxicity is like worrying about drowning when you are dying of thirst" Dr. Cannell
- Anecdote: 50,000 IU daily for 10 days given to people who live with person infected by COVID-19 ==> prevented infection
- Rhonda Patrick on Joe Rogan May 17, 2020
- Philippines: every standard deviation ==> 8 times more likely chance to have a mild
- Indonesia: only 4% of patients with sufficient vitamin D died.
- Blacks 2X as likely to die from COVID-19 than whites in England
- Daily or weekly vitamin D reduced the risk of acute respiratory infection by more than 50%
- Vitamin D normalizes ACE2 receptor levels in animals
- The Cheapest COVID-19 Therapy in the World May 24, 2020
- Doctor Mike Hansen - 2 nice videos discussing Vitamin D science and interaction with COVID-19
- Vitamin D3, Vitamin D2 and Calcitriol May 21, 13 minutes Does Vitamin D help with Immunity? May 30, 2020 13 minutes
- COVID-19 - Do You Need to Start Getting This Vital Nutrient? Mercola May 31, 2020
- Video with Hollis, Wagner, and Baggerly of Vitamin D and COVID-19; a 2nd video of Wagner on the immune system
- Understanding—COVID-19: Actions For Mitigating Risks—Facts & Myths Sunil Wimalawansa, 90 minutes May 27, 2020
- Dr. Campbell (has daily COVID-19 videos) COVID-19 and Vitamin D May 9, 2020
- Dr. Coimbra: Vitamin D and COVID, 88 minutes in Portuguese May 1, 2020
- Click here for transcript in many languages
- COVID-19 and Vitamin D 30 minute updated May 12, 2020 excellent, Renu Mahtani
- previous version, taken down by YouTube, had 600,000 views, >2,000 comments
- for people who have not been taking any vitamin D she recommends Business World May 22
- Vitamin D 60k IU twice a week for two weeks to be followed by 60k once a week for the next six weeks.
- or Vitamin D 60k IU daily for three days to be followed by 60k weekly for the total period of two months.
- Could Vitamin D Help with COVID-19 April 9, 2020 India
- Vitamin D against Viral Infections: Antiviral Nutrition 2020 (excerpt 3) by Dr. Alex Vasquez March 6, 2020 8 minutes
- Vitamin D for respiratory infections April 18 Rishi Desai CDC Viral Infections
- Could Vitamin D Help with COVID-19? April 6, 2020
- Vitamin D and Immunity, Lots of Evidence April 15, 2020 Dr. Campbell
- Vitamin D normalizes the ACE2, which is the attachment point for COVID-19 virus Dr. Patrick Video April 12, 2020
- Her video reviews about a dozen publications. Her description of the importance of vitamin D starts at 24:52
- Many videos by Sunil Wimalawansa April 12-- - , 5-10 minutes each
- He is starting a Randomized Controlled Trial in Sri Lanka for COVID-19 treatment by Vitamin D - not described in the videos
- 20: Vitamin D & COVID-19
- 21: How does vitamin D reduce COVID-19 infection?
- 22: What is ACE2 receptor, through which COVID-19 enters cells
- 23: How does COVID-19 kill us?
- 26: How does vitamin D reduce COVID-19 infection
- 44: What have we learned during the past 2 weeks on COVID-19?
- 45: How vitamin D help to attenuate COVID-19?
- 48: Herd immunity and the importance of testing
- 53 Reducing the severity of COVID-19 with vitamin D adequacy
- 54: Tropical countries, warm weathwer, and lower deaths due to COVID-19
- See also Video May 27 90 minute
- Dr. Eric Berg DC April 5 - one of his many vitamin D videos
- Take 100,000 IU of vitamin D, and again 3 months later to prevent COVID-19 Dr. Anderson March 22
Groups which actively ignore Vitamin D possibility
- The Wellcome-Gates COVID-19 Accelerator initiative expressly prohibits funding for Vitamins.
Why/How Vitamin D both treats and prevents virus
- Coronaviruses attach to cells via ACE2, Vitamin D might reduce ACE2
- All previous Coronarvirus have been treated by Vitamin D
- Most enveloped virus are treated by Vitamin D
- Vitamin D can inhibit enveloped virus (e.g. Corona, Herpes, Zoster, Epstein, Hepatitis, RSV) – March 2011
- Also: cytomegalovirus, retrovirus-like HIV, Dengue, Yellow fever. Measles, Mumps, smallpox
- The interplay between vitamin D and viral infections – Jan 2019
- Influenza virus might be prevented and treated by Vitamin D, if no vaccination – Aug 2018
- Influenza prevented by 40 ng levels or treated with vitamin D hammer (50,000 IU) – June 2015
- Influenza of 1918 and vitamin D - July 2010 -an H1N1 that was strongly associated with low vitamin D
- Dengue fever - 8X higher risk for getting worse if low vitamin D – Sept 2017
- Immune system is fortified by Vitamin D (other supplements help too)
- Overview Colds and flu and Vitamin D
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