Incidence of myocardial infarction and associated mortality varies by latitude and season: findings from a Swedish Registry Study.
J Public Health (Oxf). 2019 Nov 28. pii: fdz131. doi: 10.1093/pubmed/fdz131
Harvey NC1,2, Lorentzon M3,4, Kanis JA5,6, McCloskey E5,7, Johansson H5,6.
Cardiovascular death 1.5X more likely if less than 20 ng of Vitamin D – 22nd meta-analysis Nov 2019
Cardiovascular deaths 12 percent less likely if have 10 ng more vitamin D – meta-analysis March 2017
perhaps need 10 ng more vitamin D for every 10 degrees further from equator
Vitamin D varies with latitude has the following
Higher incidence of many health problems if Higher Latitude
- Many diseases increase with latitude (low UV, Vitamin D) many "smile" charts
- Dementia risk increases with latitude (less vitamin D) - Feb 2015 Sweden
- Schizophrenia and vitamin D have latitude-related genes – Nov 2010
- Headaches vary with latitude and season and perhaps vitamin D as well -May 2010
- Many autoimmune diseases associated with latitude and vitamin D receptor – March 2016
- Rheumatoid Arthritis associated with lower vitamin D and higher latitude – meta-analysis Jan 2016
- Crohn’s disease associated with vitamin D and latitude – meta-analysis Dec 2015
- Autism and Vitamin D massive review – latitude, season, migration, VitD levels and intervention – April 2016
- Mortality varies with latitude in the UK – Feb 2011
Cancer and Latitude
- Breast Cancer vs latitude
- Non-melanoma skin cancer varies with latitude, melanoma does not – April 2017
MS and latitude
- Why has the MS latitude gradient disappeared – Oct 2011 - reasons might apply to other diseases as well
- MS is related to latitude – conclusion from 321 studies – April 2011
- Multiple Sclerosis incidence varies with latitude (noted in Brazil too) – Nov 2015
Cardiovascular category starts with the following
- Overview Cardiovascular and vitamin D
- Hypertension and vitamin D
- Overview Metabolic Syndrome and vitamin D
- Overview Stroke and vitamin D
- Peripheral arterial disease risk is 1.5X higher if low vitamin D – meta-analysis March 2018
- Peripheral Arterial Disease 3.7 X more likely in diabetics with low vitamin D – June 2019
- Heart attack ICU costs cut in half by Vitamin D – Oct 2018
- Heart Failure and Vitamin D meta-analyses - 2016, 2019
- Cardiovascular death 1.5X more likely if less than 20 ng of Vitamin D – 22nd meta-analysis Nov 2019
- Vitamin D supplementation reduces many Cardiovascular Disease markers– meta-analysis July 2018
- Cardiovascular Prevention with Omega-3 (finally using high doses) – Sept 2019
- Higher Omega-3 index (4 to 8 percent) associated with 30 percent less risk of coronary disease (10 studies) July 2017
A poor Vitamin D Receptor can block Vitamin D in blood from getting to tissues
- Heart Failure 15X more likely if poor VDR, even if good level of vitamin D (China) – March 2019
- Coronary Artery Disease without diabetes 5 times more likely if VDR gene problems – meta-analysis May 2016
- Cholesterol is needed to produce both Vitamin D and Cortisol
- Overview Cholesterol and vitamin D
- Statins and vitamin D statins often reduce levels of vitamin D
- Statin side-effects are reduced by Vitamin D – US patent Application – April 2019
We investigated whether the incidence of death following myocardial infarction (MI) varied by season and latitude in the Swedish population.
We studied deaths following MI from January 1987 to December 2009, using the Swedish National Cause of Death Register. County of residence was used to determine latitude and population density. An extension of Poisson regression was used to study the relationship between risk of death following MI with age, latitude, time (from 1987), population density and calendar days.
Over the study period, there was a secular decrease in the incidence of MI-related death.
In men, MI-related death incidence increased by 1.3% [95% confidence interval (CI) = 1.1-1.5] per degree of latitude (northwards).
In women, MI-related death incidence increased by 0.6% (95% CI = 0.4-0.9) per degree of latitude.
There was seasonal variation in the risk of MI-related death with peak values in the late winter and a nadir in the summer months in both the north and the south of Sweden. Findings were similar with incident MI as the outcome.
The incidence of MI-related death varied markedly by season and latitude in Sweden, with summer months and more southerly latitude associated with lower rates than winter months and more northerly latitude.