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Healthy aging associated with higher levels of both Vitamin D and Omega-3 – Dec 2018

Nutr Hosp. 2018 Dec 3;35(6):1287-1297. doi: 10.20960/nh.1946.
Lozano Relaño M1, Manyes L, Peiró J, Ramada JM.


13 reasons why many seniors need more vitamin D (both dose and level) - July 2023 has the following

  1. Senior skin produces 3X less Vitamin D for the same sun intensity
  2. Seniors have fewer vitamin D receptor genes as they age
    Receptors are needed to get Vitamin D in blood actually into the cells
  3. Many other Vitamin D genes decrease with age
  4. Since many gene activations are not detected by a blood test,
    more Vitamin D is often needed, especially by seniors
  5. Seniors are indoors more than when they were younger
    not as agile, weaker muscles; frail, no longer enjoy hot temperatures
  6. Seniors wear more clothing outdoors than when younger
    Seniors also are told to fear skin cancer & wrinkles
  7. Seniors often take various drugs which end up reducing vitamin D
    Some reductions are not detected by a vitamin D test of the blood
    statins, chemotherapy, anti-depressants, blood pressure, beta-blockers, etc
  8. Seniors often have one or more diseases that consume vitamin D
    osteoporosis, diabetes, Multiple Sclerosis, Cancer, ...
  9. Seniors generally put on weight at they age - and a heavier body requires more vitamin D
  10. Seniors often (40%) have fatty livers – which do not process vitamin D as well
  11. Reduced stomach acid means less Magnesium is available to get vitamin D into the cells
  12. Vitamin D is not as bioavailable in senior intestines
  13. Seniors with poorly functioning kidneys do not process vitamin D as well
       Seniors category has 407 items

Items in both categories Seniors and Omega-3 are listed here:

several indexes are used to measure the quality of nutrition in advanced ages. None of them were designed to evaluate nutrition to avoid disabilities in elderly population.

to retrieve from literature "nutrients and intakes" showing to be involved in aging, and propose a new index, considering this information, to evaluate the quality of nutrition for preventing diseases related to aging.

a bibliographic review was performed, retrieving information on nutrients associated with aging. All these nutrients were incorporated into a new Healthy Aging Diet Index (HADI). Next, a cross-sectional study was carried out with two convenience samples of elderly, collecting the nutritional and dietary data, calculating different validated indexes and comparing them with HADI to validate the results.

forty-eight manuscripts were retrieved for full-text analysis. Associations were found between

cardiovascular diseases

  • macronutrients,
  • dietary fibre,
  • sodium and
  • vitamin D


  • fatty acids


  • fatty acids
  • fibre and
  • simple sugars;


  • calcium
  • vitamin D


  • proteins,
  • calcium
  • vitamin D

cognitive impairment

  • fatty acids
  • folates.

Sample 2, associated with rural areas, obtained lower indexes' scores. The behavior of HADI is similar to the other indexes (6.24/14 and 6.10/14 in samples 1 and 2, respectively).

the presented collection of nutrients adds useful evidence for the design of diets that allow healthy aging. The new index proposed is a tool of specific nutritional measurement in studies aimed to prevent diseases related to aging.

Created by admin. Last Modification: Wednesday December 12, 2018 13:22:45 GMT-0000 by admin. (Version 3)