A Study to Assess Anti-Inflammatory Effect of Vitamin D on Gingivitis: A Dose Dependent Randomised Controlled Trial
J Pharm Bioallied Sci. 2023 Jul; 15(Suppl 2): S1182–S1184. doi: 10.4103/jpbs.jpbs_169_23
Rahul Srivastava,1 Hadi Raza,2 Pooja Kabra,3 Ashtha Arya,4 Athira Purushothaman,2 and Pallavi A. Thomas5
Introduction:
Vitamin D deficiency increases gingivitis risk. Studies show that higher vitamin D levels reduce inflammation.
Materials and Methods:
College conducted a double-blind, randomized, controlled trial on 451 people’s vitamin D and gingival health at baseline. For three months, participants were given a placebo (group A), 1000 international units (IU) of vitamin D3 per day (group , 500 IU per day (group C), or 2000 IU per day (group A). Gingival scores were recorded for three months to assess the anti-inflammatory effect (the first, second, and third). Vitamin D levels also affected gingivitis.
Results:
Vitamin D dose-dependently reduces gingivitis inflammation. Vitamin D administration negatively correlated with gingival index score. Anti-inflammatory vitamin D levels are 32–37 ng/ml.
Conclusion:
Vitamin D supplementation can reduce gingivitis severity. The optimal blood vitamin D level is 30–35 ng/ml.
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VitaminDWiki – Dental category contains:
Some Dental studies
- Vitamin D cut dental caries in half 80 years ago – meta-analysis 2013 80 years ago
- Caries (tooth decay) and Vitamin D - 23+ studies
- Periodontitis reduced by Vitamin D - many studies
- Risk of Oral Surgery reduced by Vitamin D – scoping review Nov 2021
- Some Dental Malocclusions 5X more likely if low vitamin D – June 2021
- Grinding teeth while sleeping (sleep bruxism) 6 X more likely if low vitamin D – Jan 2021
- Early tooth decay 1.9 X more likely if a poor Vitamin D receptor – July 2017
7 Intervention AND Dental studies 19 items listed in BOTH Dental and Infant or Child 7 listed in BOTH Dental and Vitamin D Receptor
VitaminDWiki – Strontium and vitamin D patented in 2008 for periodontitis, gingivitis
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