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Fractures reduced by monthly 30,000 IU of Vitamin D, perhaps 100,000 IU would be better – July 2019

Should vitamin D administration for fracture prevention be continued? :
A discussion of recent meta-analysis findings.

Zeitschrift fur Gerontologie und Geriatrie (PMID:31263959), DOI: 10.1007/s00391-019-01573-9
Bischoff-Ferrari HA 1

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Falls and Fractures category contains the following


Pages listed in BOTH the categories Falls/Fracture and Meta-analysis

 Download the PDF from Sci-Hub via VitaminDWiki

In consideration and critical review of four recent meta-analyses on vitamin D and fracture prevention, vitamin D supplementation with or without calcium is supported among older adults age 65 years and older at risk of vitamin D deficiency and fractures if given in daily or equivalent weekly or monthly doses of 800 to 1000 IU and with good adherence. Vitamin D supplementation might not be effective in primary prevention among adults age 50 years and older without vitamin D deficiency and osteoporosis; however, clinical trials on primary prevention are limited. Notably, large annual bolus administration of vitamin D is detrimental with regard to falls and fractures among older adults at risk of fractures and should not be continued in clinical care. Larger monthly doses of 100,000 IU need further evaluation with respect to efficacy and safety.

Created by admin. Last Modification: Wednesday July 17, 2019 20:12:00 GMT-0000 by admin. (Version 4)

Attached files

ID Name Comment Uploaded Size Downloads
12273 FF 100,000.pdf PDF 2019 admin 07 Jul, 2019 11:32 293.73 Kb 16
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