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Fertility of men and women reduced by obesity and low vitamin D (perhaps synergistically) – June 2019

Vitamin D and Obesity: Two Interacting Players in the Field of Infertility.

Nutrients. 2019 Jun 27;11(7). pii: E1455. doi: 10.3390/nu11071455.
Bosdou JK1, Konstantinidou E2, Anagnostis P3, Kolibianakis EM1, Goulis DG2.


Items in both categories Obesity and Fertility are listed here:

Items in both of the categories Intervention AND Fertility/Sperm

Fertility and Sperm category contains the following summary

140 items in Fertility or Sperm in VitaminDWiki

See also:
Overview Women and Vitamin D
Overview Pregnancy and vitamin D    Fertility and Vitamin D – several articles
Ensure a healthy pregnancy and baby - take Vitamin D before conception
IVF OR "IN VITRO FERTILIZATION" etc. in 18 VitaminDWiki titles

 Download the PDF from VitaminDWiki
(This article belongs to the Special Issue Vitamin D and Obesity)

Obesity plays an important role in human fertility in both genders.
The same is true for vitamin D, for which accumulating evidence from observational human studies suggests a key role for both male and female fertility. In the latter case, however, robust data from relevant interventional studies are currently lacking.
It is also not clear whether obesity and vitamin D deficiency, besides their independent effect on human infertility, act in synergy.
Several pathogenetic mechanisms may be proposed as a linkage between vitamin D deficiency and obesity, with respect to infertility. In any case, the independent contribution of vitamin D deficiency in obese infertile states needs to be proven in interventional studies focusing on either vitamin D supplementation in obese or weight loss strategies in vitamin D-deficient infertile patients.

Table 1. Vitamin D and infertility

Male infertility
Linear or U-shaped correlation between vitamin D concentrations and sperm motility/morphology
Sufficient vitamin D concentrations associated with high testosterone concentrations
Supplementation of vitamin D improved semen quality and pregnancy rates
Supplementation of vitamin D increased testosterone concentrations
Female infertility
Contradictory data on whether supplementation of vitamin D is associated with pregnancy rates
ART (assisted reproductive techniques)
Higher live birth rates in vitamin D-sufficient women
Linear correlation between vitamin D concentrations and diameter of ovarian endometriomas
Higher incidence of vitamin D deficiency/insufficiency in women with endometriosis
PCOS (polycystic ovary syndrome)
Linear correlation between vitamin D levels and reproductive success rates after ovulation induction in women with PCOS

Created by admin. Last Modification: Monday December 23, 2019 22:56:18 GMT-0000 by admin. (Version 8)

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