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Diabetes in child not prevented by a tiny amount of vitamin D during pregnancy – Nov 2015

No association between use of multivitamin supplement containing vitamin D during pregnancy and risk of Type 1 Diabetes in the child.

Pediatr Diabetes. 2015 Nov 10. doi: 10.1111/pedi.12334. [Epub ahead of print]
Granfors M1, Augustin H1, Ludvigsson J2, Brekke HK1,2.

VitaminDWiki

The PDF defines supplemementation as > 80 IU of vitamin D
It is rare for prenatal vitamins to have as much as 400 IU of vitamin D
See also VitaminDWiki


BACKGROUND:
Sweden has the second highest incidence of type 1 diabetes in the world. Nutritional aspects in utero and in infancy affect the development. We conducted a survey to determine whether reported maternal use of vitamin D-containing micronutrient supplements during pregnancy was associated with the risk of developing type 1 diabetes in the child.
METHODS:
This report was based on data from the ABIS (All Babies In Southeast Sweden) study, with questionnaire data on 16 339 mother and infant pairs at birth and at 1-yr of age (n = 10 879), of whom 108 children were registered with type 1 diabetes before 14-16 yr of age. The questions 'during pregnancy, did you take any vitamin/mineral supplements?' and 'if yes, which? (open answer)' in addition to other lifestyle questions were answered. Logistic regression was performed with onset of type 1 diabetes as the dependent variable and vitamin D supplementation use as the independent variable, adjusted for relevant factors.
RESULTS:
Vitamin D supplementation during pregnancy was consumed by 9.3% of mothers whose children later got type1 diabetes and among 11.3% of those mothers whose children did not get type 1 diabetes (p = 0.532). No significant association was found between reported supplement intake of vitamin D during pregnancy and risk of type 1 diabetes, even when adjusting for factors which could influence the association.
CONCLUSION:
Maternal use of vitamin D-containing multivitamin supplements during pregnancy was not related to the risk of developing type 1 diabetes in children before 14-16 yr of age in Southeast of Sweden.

© 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

PMID: 26552946

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