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Diabetes 5.6 X more likely if low vitamin D 4 years before – March 2018

Vitamin D and Incidence of Prediabetes or Type 2 Diabetes: A Four-Year Follow-Up Community-Based Study

Disease Markers, Vol 2018, Article ID 1926308, 8 pages, https://doi.org/10.1155/2018/1926308
Yun Gao,1 Tianpeng Zheng,2 Xingwu Ran,1 Yan Ren,1 Tao Chen,1 Li Zhong,3 Donge Yan,4 Fangfang Yan,1 Qianlin Wu,1 and Haoming Tian1


Measured Vitamin D blood levels in non-diabetics (average age 45)
4 years later

Vitamin D LevelPrediabetes occurance
Increase Risk
Diabetes occurance
Increase Risk
5.58 – 13.42 ng/ml 49%
3 X
16 %
5.6 X
13.43 – 16.04 ng/ml
16.05 – 18.55 ng/ml
18.56 – 32.12 ng/ml 11

See also VitaminDWiki

Overview Diabetes and vitamin D contains the following summary

  • Diabetes is 5X more frequent far from the equator
  • Children getting 2,000 IU of vitamin D are 8X less likely to get Type 1 diabetes
  • Obese people get less sun / Vitamin D - and also vitamin D gets lost in fat
  • Sedentary people get less sun / Vitamin D
  • Worldwide Diabetes increase has been concurrent with vitamin D decrease and air conditioning
  • Elderly get 4X less vitamin D from the same amount of sun
        Elderly also spend less time outdoors and have more clothes on
  • All items in category Diabetes and Vitamin D 481 items: both Type 1 and Type 2

Vitamin D appears to both prevent and treat diabetes

  • Appears that >2,000 IU will Prevent
  • Appears that >4,000 IU will Treat , but not cure
  • Appears that Calcium and Magnesium are needed for both Prevention and Treatment
    • which are just some of the vitamin D cofactors

Number of articles in both categories of Diabetes and:

  • Dark Skin 23;   Intervention 52;   Meta-analysis 34;   Obesity 29;  Pregnancy 40;   T1 (child) 37;  Omega-3 11;  Vitamin D Receptor 21;  Genetics 11;  Magnesium 19    Click here to see details

Diabetes category starts with the following

481 items In Diabetes category

see also Overview Diabetes and vitamin D  Overview Metabolic Syndrome and vitamin D

Autoimmune category listing has 178 items along with related searches

T1 diabetes OR type1 diabetes in title 107 as of April 2018
prediabetes OR prediabetic 1260 items as of April 2021
Search VitaminDWiki for Peripheral Neuropathy 238 items April 2018

 Download the PDF from VitaminDWiki

Aim. To examine whether the baseline 25-hydroxyvitamin D [25(OH)D] level was predictive of the onset of prediabetes or type 2 diabetes (T2DM) in the Chinese population.

Methods. This was a 4-year follow-up study that was conducted in the Chengdu region of China as part of the China National Diabetes and Metabolic Disorders Study. The study included 490 participants that were free of prediabetes and type 2 diabetes mellitus (T2DM) at baseline and had complete data by follow-up examinations. Glucose, insulin, and 25(OH)D levels were measured at baseline and at 4 years later. Prediabetes and T2DM were defined by results obtained from an oral glucose tolerance test.

Results. Over a 4-year follow-up, 95 (48.5‰) developed prediabetes and 31 (15.8‰) individuals developed diabetes. Low 25(OH)D status was significantly associated with the risk of developing prediabetes [OR 3.01 (95% CI: 1.50–6.06), ] and T2DM [OR 5.61 (95% CI: 1.73–18.27), ] after adjustment for multiple potential confounders. In a multiple linear regression analysis, low baseline levels of 25(OH)D were an independent predictor of increased insulin resistance over a 4-year period ().

Conclusions. The current prospective study suggests that low 25(OH)D levels might have contributed to the incidence of prediabetes or T2DM in Chinese individuals.

This trial is registered with TR-CCH-ChiCTR-OCS-09000361.

Created by admin. Last Modification: Thursday May 17, 2018 10:14:42 GMT-0000 by admin. (Version 4)

Attached files

ID Name Comment Uploaded Size Downloads
9872 China diabetes 4 year.pdf PDF 2018 admin 17 May, 2018 10:01 1.48 Mb 292
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