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Diabetes (Type I, in males) became seasonal (with birth) when vitamin D supplementation was removed – Oct 2015

Vitamin D fortification and seasonality of birth in type 1 diabetic cases: D-tect study.

J Dev Orig Health Dis. 2015 Oct 27:1-6. [Epub ahead of print]
Jacobsen R1, Moldovan M2, Vaag AA3, Hypponen E2, Heitmann BL1.
1 Research Unit for Dietary Studies, The Parker Institute, Frederiksberg Hospital, Frederiksberg, Denmark.
2 School of Population Health, University of South Australia, Adelaide, Australia.
3 Department of Endocrinology, Rigshospitalet, Copenhagen, Denmark.

Fortification of margarine with vitamin D was mandatory in Denmark during 1961-1985. The aim of the study was to assess whether gestational and early infancy exposure to margarine fortification was associated with seasonality of birth in Danish type 1 diabetes (T1D) patients. The risks of T1D in Danes born during various exposure periods around margarine fortification termination in 1985 were analyzed.
As expected, the T1D hazards in males unexposed to margarine fortification and born in spring were higher than in males born in autumn: relevant hazard ratios (95% confidence intervals) in various exposure groups ranged from 1.74 (1.112/2.708) to 37.43 (1.804/776.558).
There were no indications of seasonality of birth in males exposed to fortification, nor in both exposed and unexposed females. The study suggests that early life exposure to low-dose vitamin D from fortified food eliminates seasonality of birth in T1D male patients. Further studies are required to investigate the identified gender differences.

PMID: 26503327

How much vitamin D in was in the margarine?

See also VitaminDWiki

  • Diabetes is 5X more frequent far from the equator
  • Children getting 2,000 IU of vitamin D are 8X less likely to get Type 1 diabetes
  • Obese people get less sun / Vitamin D - and also vitamin D gets lost in fat
  • Sedentary people get less sun / Vitamin D
  • Worldwide Diabetes increase has been concurrent with vitamin D decrease and air conditioning
  • Elderly get 4X less vitamin D from the same amount of sun
        Elderly also spend less time outdoors and have more clothes on
  • All items in category Diabetes and Vitamin D 447 items: both Type 1 and Type 2

Vitamin D appears to both prevent and treat diabetes

  • Appears that >2,000 IU will Prevent
  • Appears that >4,000 IU will Treat , but not cure
  • Appears that Calcium and Magnesium are needed for both Prevention and Treatment
    • which are just some of the vitamin D cofactors

Number of articles in both categories of Diabetes and:

  • Dark Skin 22;   Intervention 48;   Meta-analysis 28;   Obesity 26;  Pregnancy 39;   T1 (child) 33;  Omega-3 10;  Vitamin D Receptor 18;  Genetics 9;  Magnesium 18    Click here to see details
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