Toggle Health Problems and D

Depression is often associated with low D and treated by Vitamin D – April 2022

Depression and Vitamin D: A Peculiar Relationship

Cureus. 2022 Apr 21;14(4):e24363. doi: 10.7759/cureus.24363
Nisha Saji Parel 1, Parimi Vamsi Krishna 2, Anuradha Gupta 3, Kamsika Uthayaseelan 4, Kivonika Uthayaseelan 5, Monika Kadari 6, Muhammad Subhan 7, Sripada Preetham Kasire 8

List of criteria


Randomized Controlled Trials


Depression is a psychiatric disorder characterized by various symptoms that can impact one's quality of life. Vitamin D, a fat-soluble vitamin, is well-known for its role in bone health, and research on its effects on mental health has only recently emerged. Vitamin D deficiency is widespread worldwide, and it has been linked to an increased risk of depression. In this article, we have discussed different hypotheses that explain the role of vitamin D in gene expression and its effects on neurotransmitters and different brain functions. We have reviewed literature that shows us that Vitamin D deficiency is a risk factor for depression and explored studies that show us the effects of using or supplementing Vitamin D in preventing depression among various populations.

 Download the PDF from VitaminDWiki

Intervention of Vitamin D for Depression

Meta-analyses of Vitamin D and Depression

VitaminDWiki - Depression summary

VitaminDWiki - Suicide associated with low vitamin D contains

Hints that suicide is associated with low vitamin D:

  1. Suicide peaks in the Spring, when vitamin D values are lowest
  2. Suicide has increased while vitamin D has been decreasing
  3. Suicide higher in dark-skinned individuals (low vitamin D due to built-in sun protection)
  4. Suicide higher in prison (shut-ins have low levels of vitamin D)
  5. Suicide attempts in males 3.7 X more likely if poor CYP24A1 gene (less D to cells)
  6. Suicide rate is higher at high latitudes (where vitamin D is less available)
    See Criteria to associate a health problem with low vitamin D

Created by admin. Last Modification: Sunday June 5, 2022 16:43:11 GMT-0000 by admin. (Version 4)

Attached files

ID Name Comment Uploaded Size Downloads
17709 Depression trials.jpg admin 01 Jun, 2022 10:43 179.61 Kb 130
17708 Depression Criteria.jpg admin 01 Jun, 2022 10:43 26.04 Kb 96
17707 Depression and Vitamin D - A Peculiar Relationship.pdf PDF 2022 admin 01 Jun, 2022 10:35 171.28 Kb 67