Loading...
 
Toggle Health Problems and D

Chinese COVID-19 study – 80 pct of severe cases had low Vitamin D, all asymptomatic cases had OK Vit D – Oct 13, 2020

Does Serum Vitamin D Level Affect COVID-19 Infection and Its Severity?-A Case-Control Study

Journal of the American College of Nutrition https://doi.org/10.1080/07315724.2020.1826005
Kun Ye,Fen Tang,Xin Liao,Benjamin A. Shaw,Meiqiu Deng,Guangyi Huang, show all

VitaminDWiki

Reported by Grassroots Health Nov 4, 2020

Image


COVID-19 treated by Vitamin D - studies, reports, videos in VitaminDWiki

As of Jan 22 had:  34 trials4 trial results,  12 meta-analyses and reviews,   44 observations,   25 recommendations,   42 associations,  83 speculations,  36 videos   see also COVID-19 and Vitamin D:   Governments.   Health problems.   Hospitals

Top Vitamin D and COVID-19 recent updates

Many clinical trials are underway which are testing Vitamin D to fight COVID-19

COVID-19 RCTs

 Download the PDF from VitaminDWiki
Image

Background
As effective medication to treat COVID-19 is currently unavailable, preventive remedies may be particularly important.

Objective
To examine the relationship between serum 25-hydroxy vitamin D (25(OH)D) level and COVID-19 infection, its severity, and its clinical case characteristics.

Methods
This case-control study compared serum 25(OH)D levels and rates of vitamin D deficiency (VDD) between 80 healthy controls and 62 patients diagnosed with COVID-19 and admitted to Guangxi People’s Hospital, China, 2/16/2020–3/16/2020. Cases were categorized into asymptomatic, mild/moderate, and severe/critical disease. Logistic regression analysis was conducted to examine the associations between 25(OH)D level, or VDD, and case status/severity of COVID-19 while controlling for demographics and comorbidities. A threshold level of vitamin D for conveying COVID-19 risk was estimated.

Results
Severe/critical COVID-19 cases were significantly older and had higher percentages of comorbidity (renal failure) compared to mild cases. The serum 25(OH)D concentration in COVID-19 patient was much lower than that in healthy control. And 25(OH)D level was the lowest in severe/critical cases, compared with mild cases. In further, significantly higher rates of VDD were found in COVID-19 cases (41.9%) compared to healthy controls (11.1%). And VDD was the greatest in severe/critical cases (80%), compared with mild cases (36%). These statistically significant associations remained even after controlling for demographics and comorbidities. A potential threshold of 25(OH)D (41.19 nmol/L) to protect against COVID-19 was identified.

Conclusion
Elderly and people with comorbidities were susceptible to severe COVID-19 infection. VDD was a risk factor for COVID-19, especially for severe/critical cases. While further confirmation is needed, vitamin D supplementation may have prevention or treatment potential for COVID-19 disease.


Created by admin. Last Modification: Thursday November 5, 2020 09:26:26 GMT-0000 by admin. (Version 4)

Attached files

ID Name Comment Uploaded Size Downloads
14529 China study GRH.jpg admin 05 Nov, 2020 04:09 118.14 Kb 249
14528 China study.jpg admin 05 Nov, 2020 04:09 44.86 Kb 219
14527 Does Serum Vitamin D Level Affect COVID 19 Infection and Its Severity A Case Control Study.pdf PDF 2020 admin 05 Nov, 2020 04:08 1.20 Mb 30
See any problem with this page? Report it (FINALLY WORKS)