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Childhood Asthma risk greatly reduced if mothers were given 4,400 IU Vitamin D daily – RCT 2019

To be published in 2019
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Based on data from VDAART
Vitamin D supplementation in pregnancy, prenatal 25(OH)D levels, race, and subsequent asthma or recurrent wheeze in offspring: Secondary analyses from the Vitamin D Antenatal Asthma Reduction Trial.
J Allergy Clin Immunol. 2017;140(5):1423-9 e5.
Wolsk HM, Harshfield BJ, Laranjo N, Carey VJ, O'Connor G, Sandel M, et al.
This secondary analysis of the VDAART study is the first to show that the effect of prenatal supplementation with vitamin D on asthma and recurrent wheeze is modified by the initial maternal level of circulating vitamin D early in pregnancy. This work suggests that having a higher vitamin D level at the beginning of pregnancy and maintaining the level throughout pregnancy maximizes the preventive effect of vitamin D on asthma and recurrent wheeze in offspring.


Breathing category starts with the following

453 items in Breathing category

Breathing-related Overviews at VitaminDWiki:
Allergy   Lung Cancer   TB   Asthma  Influenza  Colds and flu
Pneumonia   Respiratory infections   COPD   Air Polution   Smoking   Cystic Fibrosis

Healthy pregnancies need lots of vitamin D has the following summary

Most were taking 2,000 to 7,000 IU daily for >50% of pregnancy
   Click on hyperlinks for details

Problem
Vit. D
Reduces
Evidence
0. Chance of not conceiving3.4 times Observe
1. Miscarriage 2.5 times Observe
2. Pre-eclampsia 3.6 timesRCT
3. Gestational Diabetes 3 times RCT
4. Good 2nd trimester sleep quality 3.5 times Observe
5. Premature birth 2 times RCT
6. C-section - unplanned 1.6 timesObserve
     Stillbirth - OMEGA-3 4 timesRCT - Omega-3
7. Depression AFTER pregnancy 1.4 times RCT
8. Small for Gestational Age 1.6 times meta-analysis
9. Infant height, weight, head size
     within normal limits
RCT
10. Childhood Wheezing 1.3 times RCT
11. Additional child is Autistic 4 times Intervention
12.Young adult Multiple Sclerosis 1.9 timesObserve
13. Preeclampsia in young adult 3.5 timesRCT
14. Good motor skills @ age 31.4 times Observe
15. Childhood Mite allergy 5 times RCT
16. Childhood Respiratory Tract visits 2.5 times RCT

RCT = Randomized Controlled Trial

Note The earlier the vitamin D levels are raised during pregnancy, the better the outcome

Ensure a healthy pregnancy and baby - take Vitamin D before conception
Start Vitamin D soon if pregnant VDW 9923

Lung development starts early during pregnancy

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Attached files

ID Name Comment Uploaded Size Downloads
11153 Lung dev during pregnancy.jpg admin 05 Jan, 2019 41.58 Kb 515
11152 Asthma 4400 IU.jpg admin 05 Jan, 2019 33.94 Kb 592