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Cardiovascular Disease is treated by Vitamin D - review Oct 2021


Cardiovascular Disease: Current Evidence and Future Perspectives.

Nutrients 2021, 13, 3603. https:// doi.org/10.3390/nu13103603
Nicola Cosentino i2, Jeness Campodonico '2, Valentina Milazzo *, Monica De Metrio 2, Marta Brambilla 2, Marina Camera 13 and Giancarlo Marenzi 1,Correspondence: giancarlo.marenzi at ccfm.it
Centro Cardiologico Monzino IRCCS, 20138 Milan, Italy; nicola.cosentino at ccfm.it (N.C.); jeness.campodonico at ccfm.it (J.C.); valentina.milazzo at ccfm.it (V.M.); monica.demetrio at ccfm.it (M.D.M.); marta.brambilla at cfm.it (M.B.); marina.camera at ccfm.it (M.C.)
Department of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy
Department of Pharmaceutical Sciences, University of Milan, 20133 Milan, Italy

Vitamin D deficiency is a prevalent condition, occurring in about 30-50% of the population, observed across all ethnicities and among all age groups. Besides the established role of vitamin D in calcium homeostasis, its deficiency is emerging as a new risk factor for cardiovascular disease (CVD). In particular, several epidemiological and clinical studies have reported a close association between low vitamin D levels and major CVDs, such as coronary artery disease, heart failure, and atrial fibrillation. Moreover, in all these clinical settings, vitamin deficiency seems to predispose to increased morbidity, mortality, and recurrent cardiovascular events. Despite this growing evidence, interventional trials with supplementation of vitamin D in patients at risk of or with established CVD are still controversial. In this review, we aimed to summarize the currently available evidence supporting the link between vitamin D deficiency and major CVDs in terms of its prevalence, clinical relevance, prognostic impact, and potential therapeutic implications.
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Note: All 4 trials use Vitamin D + Omega-3


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Created by admin. Last Modification: Thursday October 14, 2021 16:18:48 GMT-0000 by admin. (Version 8)

Attached files

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16412 CVD RCT.jpg admin 14 Oct, 2021 16:12 196.12 Kb 66
16410 Major CVD.jpg admin 14 Oct, 2021 16:08 345.45 Kb 65
16409 CVD Vitamin D interactions.jpg admin 14 Oct, 2021 16:08 47.88 Kb 80
16408 CVD Vitamin D.pdf PDF 2021 admin 14 Oct, 2021 16:07 372.92 Kb 84
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