Cardiovascular Disease is treated by Vitamin D - review Oct 2021

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Cardiovascular Disease: Current Evidence and Future Perspectives.

Nutrients 2021, 13, 3603. https:// doi.org/10.3390/nu13103603
Nicola Cosentino i2, Jeness Campodonico '2, Valentina Milazzo *, Monica De Metrio 2, Marta Brambilla 2, Marina Camera 13 and Giancarlo Marenzi 1,Correspondence: giancarlo.marenzi at ccfm.it
Centro Cardiologico Monzino IRCCS, 20138 Milan, Italy; nicola.cosentino at ccfm.it (N.C.); jeness.campodonico at ccfm.it (J.C.); valentina.milazzo at ccfm.it (V.M.); monica.demetrio at ccfm.it (M.D.M.); marta.brambilla at cfm.it (M.B.); marina.camera at ccfm.it (M.C.)
Department of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy
Department of Pharmaceutical Sciences, University of Milan, 20133 Milan, Italy

Vitamin D deficiency is a prevalent condition, occurring in about 30-50% of the population, observed across all ethnicities and among all age groups. Besides the established role of vitamin D in calcium homeostasis, its deficiency is emerging as a new risk factor for cardiovascular disease (CVD). In particular, several epidemiological and clinical studies have reported a close association between low vitamin D levels and major CVDs, such as coronary artery disease, heart failure, and atrial fibrillation. Moreover, in all these clinical settings, vitamin deficiency seems to predispose to increased morbidity, mortality, and recurrent cardiovascular events. Despite this growing evidence, interventional trials with supplementation of vitamin D in patients at risk of or with established CVD are still controversial. In this review, we aimed to summarize the currently available evidence supporting the link between vitamin D deficiency and major CVDs in terms of its prevalence, clinical relevance, prognostic impact, and potential therapeutic implications.
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Note: All 4 trials use Vitamin D + Omega-3

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Cardiovascular category in VitaminDWiki

459 items In Cardiovascular category

• Overview Cardiovascular and vitamin D
• Overview Hypertension and Vitamin D 151 items
• Overview Metabolic Syndrome and vitamin D 93 items
• Overview Stroke and vitamin D 106 items
• Cardiovascular Disease is treated by Vitamin D - review Oct 2021
• Arterial Stiffness and Vitamins – only Vitamin D was found to help – meta-analysis Feb 2022
• Those raising Vitamin D above 30 ng were 1.4 X less likely to die of Heart Attack (VA 19 years) – Oct 2021
• Giving free vitamin D to every Iranian would pay for itself by just reducing CVD – Oct 2021
• 26 health factors increase the risk of COVID-19 – all are proxies for low vitamin D
• Sudden Cardiac Arrest – 2.8 X higher risk if low vitamin D – 2019
• Cardiovascular death 1.5X more likely if less than 20 ng of Vitamin D – 22nd meta-analysis Nov 2019
• Peripheral arterial disease risk is 1.5X higher if low vitamin D – meta-analysis March 2018
• Heart attack ICU costs cut in half by Vitamin D – Oct 2018

Cardio Meta-analyses: 32 studies

(auto-updated)

Cholesterol, Statins

• Cholesterol is needed to produce both Vitamin D and Cortisol
• Overview Cholesterol and vitamin D
• Statins and vitamin D statins often reduce levels of vitamin D
• Statin side-effects are reduced by Vitamin D – US patent Application – April 2019

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Cardiovascular and Omega-3

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Cardiovascular and Magnesium

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Cardiovascular and Virus