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Cancer continues to be more deadly for Blacks than Whites (hint – low Vitamin D) – May 2022

JAMA Oncol. Published online May 19, 2022. doi:10.1001/jamaoncol.2022.1472
Wayne R. Lawrence, DrPH1; Jennifer K. McGee-Avila, PhD1; Jacqueline B. Vo, PhD1; et alQianlai Luo, PhD1; Yingxi Chen, MD, PhD1; Maki Inoue-Choi, PhD1; Amy Berrington de González, DPhil1; Neal D. Freedman, PhD1; Meredith S. Shiels, PhD1


Key Points
Questions How did cancer mortality among Black individuals change in the US from 1999 to 2019 by age, sex, and cancer site, and how did 2019 cancer mortality rates among Black individuals compare with rates in other racial and ethnic groups?

Findings In this cross-sectional study of 1 361 663 deaths from cancer among Black individuals, although cancer mortality decreased considerably among Black individuals from 1999 to 2019, the cancer mortality rate was higher among Black men and women than in other racial and ethnic groups in 2019.

Meaning The findings suggest that resources should be allocated toward eliminating social inequalities and barriers throughout the cancer control continuum that contribute to substantially higher cancer mortality rates among Black men and women.

Importance Cancer is the second leading cause of mortality in the US. Despite national decreases in cancer mortality, Black individuals continue to have the highest cancer death rates.

Objective To examine national trends in cancer mortality from 1999 to 2019 among Black individuals by demographic characteristics and to compare cancer death rates in 2019 among Black individuals with rates in other racial and ethnic groups.

Design, Setting, and Participants This serial cross-sectional study used US national death certificate data obtained from the National Center for Health Statistics and included all cancer deaths among individuals aged 20 years or older from January 1999 to December 2019. Data were analyzed from June 2021 to January 2022.

Exposures Age, sex, and race and ethnicity.

Main Outcomes and Measures Trends in age-standardized mortality rates and average annual percent change (AAPC) in rates were estimated by cancer type, age, sex, and race and ethnicity.

Results From 1999 to 2019, 1 361 663 million deaths from cancer occurred among Black individuals. The overall cancer death rate significantly decreased among Black men (AAPC, −2.6%; 95% CI, −2.6% to −2.6%) and women (AAPC, −1.5%; 95% CI, −1.7% to −1.3%). Death rates decreased for most cancer types, with the greatest decreases observed for lung cancer among men (AAPC, −3.8%; 95% CI, −4.0% to −3.6%) and stomach cancer among women (AAPC, −3.4%; 95% CI, −3.6% to −3.2%). Lung cancer mortality also had the largest absolute decreases among men (−78.5 per 100 000 population) and women (−19.5 per 100 000 population). We observed a significant increase in deaths from liver cancer among men (AAPC, 3.8%; 95% CI, 3.0%-4.6%) and women (AAPC, 1.8%; 95% CI, 1.2%-2.3%) aged 65 to 79 years. There was also an increasing trend in uterus cancer mortality among women aged 35 to 49 years (2.9%; 95% CI, 2.3% to 2.6%), 50 to 64 years (2.3%; 95% CI, 2.0% to 2.6%), and 65 to 79 years (1.6%; 95% CI, 1.2% to 2.0%). In 2019, Black men and women had the highest cancer mortality rates compared with non-Hispanic American Indian/Alaska Native, Asian or Pacific Islander, and White individuals and Hispanic/Latino individuals.

Conclusions and Relevance In this cross-sectional study, there were substantial decreases in cancer death rates among Black individuals from 1999 to 2019, but higher cancer death rates among Black men and women compared with other racial and ethnic groups persisted in 2019. Targeted interventions appear to be needed to eliminate social inequalities that contribute to Black individuals having higher cancer mortality.
 Study PDF
 Supplement PDF - men and women, not Black and White

VitaminDWiki Dark-skin pages with CANCER in the title (29 as of May 2022)

This list is automatically updated

Items found: 31
Title Modified
Prostate cancer patients in Jamaica were 5X more likely to die of PC if low vitamin D - Sept 2022 01 Oct, 2022
Newly diagnosed Children with Cancer have low vitamin D, especially if black - May 2022 16 Jun, 2022
Cancer continues to be more deadly for Blacks than Whites (hint – low Vitamin D) – May 2022 30 May, 2022
Cancer of breast is highest in dark-skinned women (low Vitamin D: dark skin and obese) - Feb 2022 12 Feb, 2022
Cancers and Vitamin D Receptors, including change with race – Feb 2021 24 Oct, 2021
Those with recent cancer diagnosis had 7X increased risk of COVID-19 (more if A-A )- Dec 2020 19 Feb, 2021
Deaths after Cancer Surgery higher in blacks (probably low vitamin D) – Dec 2020 10 Jan, 2021
Multiple Myeloma (blood cell cancer) treated by vitamin D - many studies 14 Jun, 2019
Blacks are more obese, have lower Vitamin D, and have more Cancer etc. than whites – Feb 2018 03 May, 2018
Hypothesis: Blacks get more cancer than whites due to lower levels of vitamin D – June 2012 03 May, 2018
Prostate Cancer risk in black men increased 2X having poor Vitamin D Binding Protein – July 2017 20 Nov, 2017
Breast cancer in blacks – 5X increased risk of triple negative if low vitamin D – Oct 2017 01 Nov, 2017
Breast cancer worse for black women – Sept 2011 19 Aug, 2017
Prostate cancer in black men is 1.6 times more likely if a poor Vitamin D Receptor – Feb 2017 06 Mar, 2017
Aggressive Prostate Cancer in blacks with low vitamin D – 7X more likely if added Calcium – Jan 2017 28 Dec, 2016
Head and Neck Cancer associated with low vitamin D, especially with blacks - April 2012 17 Nov, 2016
2X less prostate cancer in A-A with low Calcium is due vitamin D receptor gene – July 2013 14 Nov, 2016
Higher rate of prostate cancer in AA may decrease if take vitamin D – July 2016 07 Jul, 2016
Prostate Cancer incidence and death 2X more often among black men (vitamin D not mentioned) - July 2015 30 Jul, 2015
Kidney Cancer differences with skin color probably due to vitamin D differences – May 2015 25 May, 2015
Tanning potential predicts risk of Prostate Cancer in Blacks – Nov 2014 02 Jan, 2015
Cancer patients at high risk of vitamin D deficiency were not tested as often (paradoxically) – July 2014 12 Aug, 2014
Colon cancer more likely in blacks due to differences in Vitamin D genes (wonder if more Vitamin D would help) – May 2014 21 May, 2014
Barefoot on mega doses of vitamin D and his book on Cancer 10 Apr, 2014
Hypothesis - Dark skin evolved to avoid skin cancer - Feb 2014 02 Mar, 2014
Breast cancer more deadly for blacks than whites 13 Feb, 2014
Skin cancer risk and vitamin D from sun both decrease with darker skin – March 2013 10 Nov, 2013
Hypothesis: Vitamin D is related to breast cancer racial disparities in the US - Sept 2012 08 Jul, 2013
Genes may account for some of AA Breast Cancer – April 2012 08 Jul, 2013
More US deaths due to cancer than heart if dark skinned – Sept 2012 18 Sep, 2012
Low vitamin D in blacks increases colorectal cancer deaths 40 percent – Cancer Oct 2010 23 Oct, 2010

VitaminDWiki - Overview Dark Skin and Vitamin D contains

FACT - - People with dark skins have more health problems and higher mortality rate than those with light skins
FACT - - People with dark skins have low levels of vitamin D
FACT - - People with light skins who have low vitamin D have health problems
OBSERVATION - - The health problems of whites with low level of vitamin D are similar to those with dark skins
CONCLUSION - - People with dark skins have more health problems due to low levels of vitamin D
African American Health Disparities are associated with low Vitamin D - Grant Feb 2021
Low Vitamin D increases health problems - independent of skin color

Dark Skin studies: Pregnancy (27 studies),  Genetics (13 studies),  Vitamin D Binding Protein (8 studies),  Vitamin D Receptor (7 studies),  Diabetes (24 studies),   Cardiovascular (18 studies),  Mortality (12 studies), Intervention (17 studies) Click here to see the studies

VitaminDWiki - Blacks die more often than whites of many diseases (they have less vitamin D) – 2012 contains

Cancer Facts & Figures for African Americans Cancer.org

  • “African Americans have the highest death rate and shortest survival of any racial and ethnic group in the US for most cancers”
  • Has a huge number of tables and charts, Note: Vitamin D is not mentioned

Leading Causes of Death as of March 2018

All Ages Death rateBlackWhiteRatio
Heart diseases 217 1711.27
Cancer 1991701.17
Cerebrovascular diseases51361.4
Diabetes 40 192.0

Rates per 100,000    Age adjusted   Non-Hispanic

Blacks die younger than whites - 2021Image


VitaminDWiki - Skin - Dark shows some associated health problems

458 items below see also Overview Dark Skin and Vitamin D,  Overview Dark skin births and Vitamin D,  High Risk,   "Sickle Cell"

Dark Skin studies: Pregnancy (27 studies),  Genetics (13 studies),  Vitamin D Binding Protein (8 studies),  Vitamin D Receptor (7 studies),  Diabetes (24 studies),   Cardiovascular (18 studies),  Mortality (12 studies), Intervention (17 studies) Click here to see the studies

Created by admin. Last Modification: Monday May 30, 2022 22:38:13 GMT-0000 by admin. (Version 12)

Attached files

ID Name Comment Uploaded Size Downloads
17698 Cancer B-W.jpg admin 30 May, 2022 22:37 48.02 Kb 105
17697 cbr220009supp1_prod_1652382514.3696.pdf admin 30 May, 2022 22:33 1.73 Mb 80
17696 Cancers men.jpg admin 30 May, 2022 19:23 68.76 Kb 121
17694 Blacks continue to die of cancer more than whites.pdf PDF 2022 admin 30 May, 2022 19:22 284.87 Kb 85