Loading...
 
Toggle Health Problems and D

Canadian pregnancies have enough vitamin D – if white, summer, supplement, eat meat, etc. – Nov 2019

J Nutr. 2019 Nov 16. pii: nxz276. doi: 10.1093/jn/nxz276.
Perreault M1, Atkinson SA1, Meyre D2,3, Fusch G1, Mottola MF4; BHIP Study Team.

VitaminDWiki
  • 88% white,
  • 86% took supplements,
  • summer pregnancies
  • The study appears unaware that people get 6X more vitamin D from meat and eggs
    • Vit D semi-activated by animal livers: i.e. 100 gram of egg has 230 IU equiv. instead of 26 IU
  • No data collected on sun bathing nor going on sunny vacations (which is common for people in northern countries)

 Download the PDF from Sci-Hub via VitaminDWiki
Image

BACKGROUND: Vitamin D deficiency in pregnancy is reported as a prevalent public health problem.

OBJECTIVES:
We aimed to evaluate, in pregnant Canadian women, 1) vitamin D intake, 2) maternal and cord serum 25-hydroxycholecalciferol [25(OH)D] and maternal 1,25-dihydroxycholecalciferol [1,25(OH)2D], and 3) factors associated with maternal serum 25(OH)D.

METHODS:
Women (n = 187; mean prepregnancy BMI 24.4 kg/m2, mean age 31 y) recruited to the Be Healthy in Pregnancy study provided fasting blood samples and nutrient intake at 12-17 (early) and 36-38 (late) weeks of gestation, and cord blood. Vitamin D intakes (Nutritionist Pro™) and serum 25(OH)D and 1,25(OH)2D concentrations (LC-tandem MS) were measured.

RESULTS:
Vitamin D intake was comparable in early and late pregnancy [median (IQR) = 586 (459, 859) compared with 689 (544, 974) IU/d; P = 0.83], with 71% consumed as supplements. Serum 25(OH)D was significantly higher in late pregnancy (mean ± SD: 103.1 ± 29.3 nmol/L) than in early pregnancy (82.5 ± 22.5 nmol/L; P < 0.001) and no vitamin D deficiency (<30 nmol/L) occurred. Serum 1,25(OH)2D concentrations were significantly higher in late pregnancy (101.1 ± 26.9 pmol/L) than in early pregnancy (82.2 ± 19.2 pmol/L, P < 0.001, n = 84). Cord serum 25(OH)D concentrations averaged 55% of maternal concentrations. In adjusted multivariate analyses, maternal vitamin D status in early pregnancy was positively associated with summer season (est.β: 13.07; 95% CI: 5.46, 20.69; P < 0.001) and supplement intake (est.β: 0.01; 95% CI: 0.00, 0.01; P < 0.001); and in late pregnancy with summer season (est.β: 24.4; 95% CI: 15.6, 33.2; P < 0.001), nonmilk dairy intake (est.β: 0.17; 95% CI: 0.02, 0.32; P = 0.029), and supplement intake (est.β: 0.01; 95% CI: 0.00, 0.01; P = 0.04).

CONCLUSIONS:
Summer season and recommended vitamin D intakes supported adequate vitamin D status throughout pregnancy and in cord blood at >50 nmol/L in healthy Canadian pregnant women. This trial was registered at clinicaltrials.gov as NCT01693510.


Created by admin. Last Modification: Sunday November 17, 2019 14:08:16 GMT-0000 by admin. (Version 4)

Attached files

ID Name Comment Uploaded Size Downloads
12992 Canadian pregnancies.jpg admin 17 Nov, 2019 24.88 Kb 426
12991 Canada pregnancies.pdf admin 17 Nov, 2019 665.68 Kb 407