COVID-19 was 19X more likely if low vitamin D (may be invalid data)– April 2020

Vitamin D supplementation could possibly improve clinical outcomes of patients infected with Coronavirus-2019 (Covid- 2019)

Mark M. Alipio April 9, 2020
Department of Radiologic Technology, College of Allied Health Sciences, Davao Doctors College
Gen. Malvar St., Davao City 8000, Davao del Sur, Philippines, Office +63 (082) 222 0850, markalipiorrt at gmail.com

Chart of data by GrassrootsHealth

Chart of data in German VitaminDService
German vertical axis is the number of people in each group, GRH vertical axis is a % of 100%

To the Editor:
The rapid spread of Covid-2019 in many areas of the world calls for preventive health measures. Although basic guidelines on infection control are recommended, treatment has remained the best choice to avert mortality. However, for the time being, there are no known vaccines for the disease. This has driven several researchers in the world to assess the effectiveness of previously used treatments for severe acute respiratory syndrome (SARS) such as lopinavir.1 Clinical trials for these vaccines could take more time, hence, palliative drugs have been developed to alleviate the severity of the disease.
Vitamin D has been proven to reduce risk of getting common cold.2 It also enhances cellular immunity,3 modulates adaptive immunity,4 and enhances expression of antioxidation-related genes.5 Hence, several authors proposed Vitamin D supplementation to prevent and treat Covid- 2019.6,7,8 To the best of my knowledge, no clinical trials have been conducted yet to determine the potency of Vitamin D in suppressing SARS-CoV-2 strain. A statistical analysis of the association between Vitamin D levels and clinical outcomes of Covid-2019 patients has not been described. In this paper, I used multinomial logistic regression to predict clinical outcomes of patients infected with Covid-2019 based on 25-hydroxyvitamin D [25(OH)D] levels, the barometer for Vitamin D status.
Using the database of three hospitals in Southern Asian countries, I conducted a retrospective multicentre study of 212 cases with laboratory-confirmed infection of SARS-CoV-2. Data pertaining to clinical features and serum 25(OH)D levels were extracted from the medical records. No other patient information was provided to ensure confidentiality. I classified the cases as follows: (1) mild - mild clinical features without pneumonia diagnosis, (2) ordinary - confirmed pneumonia in chest computer tomography with fever and other respiratory symptoms, (3) severe
-hypoxia (at most 93% oxygen saturation) and respiratory distress or abnormal blood gas analysis results (PaC〇2 >50 mm Hg or Pa〇2 < 0 mm Hg), and (4) critical - respiratory failure requiring intensive case monitoring. Classification was based on a previous work.9 I also classified the vitamin D status of the cases based on their serum 25(OH)D level: (1) normal - 25(OH)D of > 30 ng/ml, (2) insufficient - 25(OH)D of 21-29 ng/ml, and (3) deficient - 25(OH)D of < 20 ng/ml.
A previous report guided this classification.10 For statistical analysis, I used Mann-Whitney U and x2 tests to compare differences in the clinical outcomes. Multinomial logistic regression was used to explore the association between serum 25(OH)D level and clinical outcomes of the cases. Frequency and percentage were used for categorical variables. Mean was used for continuous variables. A p-value below 0.01 was considered statistically significant. Ethics approval was considered exempt owing to the nature of the study and open-access data used. All names were originally hidden by the health governing bodies to ensure patient confidentiality.
Table 1. Descriptive statistics

Note: OR = odds ratio associated with the effect of a one standard deviation increase in the predictor.
Table 2. Multinomial logistic regression analysis

Of the 212 (100.0%) cases of Covid-2019, 49 (23.1%) were identified mild, 59 (27.8%) were ordinary, 56 (26.4%) were severe, and 48 (22.6%) were critical (Table 1). Mean serum (OH)D level was 23.8 ng/ml. Serum (OH)D level of cases with mild outcome was 31.2 ng/ml, 27.4 ng/ml for ordinary, 21.2 ng/ml for severe, and 17.1 ng/ml for critical. Serum (OH)D levels were statistically significant among clinical outcomes (p<0.001). A total of 55 (25.9%) cases had normal Vitamin D status, majority of which (85.5%) were identified mild. A total of 80 (37.7%) cases had insufficient Vitamin D status, majority of which (43.8%) were ordinary. Cases identified as Vitamin D-deficient were 77 (36.3%), majority of which were severe (40.3%).
Vitamin D status is significantly associated with clinical outcomes (p<0.001).
A multinomial logistic regression analysis reported that the odds of having a mild clinical outcome rather than an ordinary outcome were approximately 1.63 times (OR=0.614, p=0.007) for each standard deviation increase in serum (OH)D (Table 2).
Also, for each standard deviation increase in serum (OH)D, the odds of having a mild clinical outcome rather than a severe outcome were approximately 7.94 times (OR=0.126, p<0.001) while interestingly, the odds of having a mild clinical outcome rather than a critical outcome were approximately more than 19.61 times (OR=0.051, p<0.001).

More generally, the odds of having a mild clinical outcome increase when serum (OH)D level increases. Alternatively, the odds of having a critical outcome increase when serum (OH)D level decreases. This means that serum (OH)D level in the body could account for the clinical outcomes of the patients infected with Covid-2019. An increase in serum (OH)D level in the body could either improve clinical outcomes or mitigate worst (severe to critical) outcomes. On the other hand, a decrease in serum (OH)D level in the body could worsen clinical outcomes of Covid-2019 patients. In this case, Vitamin D supplementation may play an important role to raise 1,25- dihydroxyvitamin D [1,25(OH)2D], the biologically active form of Vitamin D in the blood.

In conclusion this study provides substantial information to clinicians and health policy-makers. Vitamin D supplementation could possibly improve clinical outcomes of patients infected with Covid-2019 based on increasing odds ratio of having a mild outcome when serum (OH)D level increases. Further research may conduct randomized controlled trials and large population studies to evaluate this recommendation.

References

1. Sohrabi, C., Alsafi, Z., ONeiU, N., Khan, M., Kerwan, A., Al-Jabir, A., ... & Agha, R. (2020). World Health Organization declares global emergency: A review of the 2019 novel coronavirus (COVJD-19). International Journal of Surger
2. Lei, G. S., Zhang, C., Cheng, B. H., & Lee, C. H. (2017). Mechanisms of action of vitamin D as supplemental therapy for Pneumocystis pneumonia. Antimicrobial agents and chemotherapy, 61(10), e01226-17. y.
3. Rondanelli, M., Miccono, A., Lamburghini, S., Avanzato, I., Riva, A., Allegrini, P., ... & Perna, S. (2018). Self-care for common colds: the pivotal role of vitamin D, vitamin C, zinc, and Echinacea in three main immune interactive clusters (physical barriers, innate and adaptive immunity) involved during an episode of common colds 一Practical advice on dosages and on the time to take these nutrients/botanicals in order to prevent or treat common colds. Evidence-Based Complementary and Alternative Medicine, 2018.
4. Cantorna, M. T. (2010). Mechanisms underlying the effect of vitamin D on the immune system. Proceedings of the Nutrition Society, 69(3), 286-289.
5. Sharifi, A., Vahedi, H., Nedjat, S., Rafiei, H., & Hosseinzadeh-Attar, M. J. (2019). Effect of single-dose injection of vitamin D on immune cytokines in ulcerative colitis patients: a randomized placebo-controlled trial. Apmis, 127(10), 681-687.
6. Wimalawansa, S. J. (2020). Global epidemic of coronavirus--COVID-19: What we can do to minimize risks. European XXXXX, 7(3), 432-438.
7. Grant, W. B., Lahore, H., McDonnell, S. L., Baggerly, C. A., French, C. B., Aliano, J. L., & Bhattoa, H. P. (2020). Evidence that Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths.姓/rien/s, 12(4), 988.
8. Braiman, M. (2020). Latitude Dependence of the COVID-19 Mortality Rate—A Possible Relationship to Vitamin D Deficiency?. Axx mlable at SSRN3561958.
9. Wang, Y., Liu, Y., Liu, L., Wang, X., Luo, N., & Ling, L. (2020). Clinical outcome of 55 asymptomatic cases at the time of hospital admission infected with SARS-Coronavirus-2 in Shenzhen, China. The Journal of infectious diseases.
10. Holick, M. F. (2009). Vitamin D status: measurement, interpretation, and clinical application. Annals of epidemiology, 19(2), 73-78.

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COVID-19 treated by Vitamin D - studies, reports, videos

As of April 29, 2022, the VitaminDWiki COVID page had:  19 trial results,   37 meta-analyses and reviews,   Mortality studies   see related:   Governments,   HealthProblems,   Hospitals,  Dark Skins,   26 risk factors are ALL associated with low Vit D,   Fight COVID-19 with 50K Vit D weekly   Vaccines   Take lots of Vitamin D at first signs of COVID   126 COVID Clinical Trials using Vitamin D (March 2023)   Cost to prevent a COVID death: 11 dollars of Vitamin D - Nov 2022
5 most-recently changed Virus entries

Vitamin D and COVID-19 - - - (since Sept 2021)

• Children with COVID 4X more likely to have poor Vitamin D Receptors (Note: COVID deactivates VDR) – April 2023
• 3,400 peer-reviewed studies found COVID Vaccination problems as of April 2023
• COVID death 1.5 X less likely if high vitamin D, emergency D (50K to 100K) is great – meta-analysis March 2023
• Poor vaccine batches associated with adverse events - March 2023
  • Probably less of a problem if had high Vitamin D when vaccinated
• Excess deaths - 5 possible reasons - many studies
  • Probably multiple vaccinations wears out the immune system
  • Perhaps high vitamin D when vaccinated will not wear out the immune system 1  2   3
• COVID was associated with low Vitamin D or Zinc – umbrella review Feb 2023
• COVID predicted to be a pandemic that could be stopped by high dose vitamin D - Feb 2020
• COVID and other Virus fought by UV - many studies
• Seniors raised Vitamin D levels, more COVID survivors, less CKD (Slovakia) – Feb 2023
• COVID recovery 1.6X faster after 200,000 IU of Vitamin D RCT – Feb 2023
• Multisystem Inflammatory Syndrome of COVID in Children 3X more likely if low Vitamin D – Feb 2023
• COVID was associated with low Vitamin D or Zinc – umbrella review Feb 2023
• Vitamin D, now conclusive (for COVID) - Dr. Campbell Video and transcript - Feb 1, 2023
• COVID ICU 3X less-likely if take any amount and type of Vitamin D – meta-analysis Jan 2023
• 2nd COVID infection increases the risk of Long-COVID - 2022
• More COVID vaccinations, more infections - Cleveland Clinic - Dec 2022
  • 
• COVID vaccination increased by 137X the risk of 10-14 year olds of dying (UK) – Jan 2023
• Chart of excess deaths and vaccination in the Netherlands - for 2022
• China: From Zero Covid to No Plan - people left to improvise - NYT Dec 18, 2022
• COVID variants in US evade bivalent vaccination by 3X to 13X – Cell Dec 13, 2022
• Fight infections such as COVID with 50 ng of Vitamin D – Sunil Dec 2022
• COVID and Vitamin D: any amount of D, at any time, for any duration reduced ICU - meta-analysis Dec 2022
• The vitamins and minerals that help the immune system respond to respiratory viruses – Dec 2022
• The COVID supplement with the most publications: Vitamin D – Nov 2022
• 23 COVID mitigation strategies: at least 6 of which increase Vitamin D in cells - Sept 2022
• Severe COVID 1.8 X more likely in pregnant women with less than 15 ng of vitamin D – Nov 2022
• Long-COVID fatigue reduced by Vitamin C and l-Arginine in one month– RCT Nov 2022
• COVID 2X more likely to be severe if low Vitamin D in previous month (Denmark, May 2020) – Nov 2022
• Respiratory viral infection (RSV) and low vitamin D - many studies
• T1 Diabetic adults 5X more likely to get COVID (hint low vitamin D)– Nov 2022
• Cost to prevent a COVID death: 11 dollars of Vitamin D - Nov 2022
• COVID US deaths: 116,000 fewer if everyone had been taking 50,000 IU Vitamin D – Campbell transcript Nov 2022
• COVID existed in the second half of 2019 - several studies nothing about Vitamin D
• PICU layoffs due to pandemic lulls, but children are now getting 3 years of viral infection all at once – Oct 2022 nothing about Vitamin D
• Fatigue and other long-haul problems appear to be associated with low Magnesium - Chambers Oct 2022
• Long-COVID symptoms in 10 Percent of women 3 months after infection (22 countries) – Oct 2022 nothing about Vitamin D
• COVID-Osteoporosis association appears to be low Vitamin D – Oct 2022
• Low Magnesium associated with severe COVID – many studies
• 10,000 COVID infections: Hospitalization 2.4X more likely if low vitamin D - Oct 2022
• BIDEN: "Almost everyone who will die from COVID this year will not be up to date on their shots." (nope) - Oct 2022
• Tripledemic: Flu, COVID, and RSV (all fought by Vitamin D) - Oct 2022
• COVID: more than 33 lineages and vaccines – Nov 2022 nothing about Vitamin D
• 1,000 X lower COVID mortality rate in 2020 for age 10 vs 65 – Oct 2022
• COVID 5.5 X more likely to be severe if low Vitamin D (children in this case) – Oct 2022
• Vitamin D was the most popular nutraceutical to avoid COVID – 41 percent of dentists in Brazil – Oct 2022
• The more COVID vaccinations you get, the More Likely you’ll get COVID - Oct 2022
• CDC v-safe vaccination data is finally on-line - Oct 5, 2022
• 400 doctors, scientists declare “international medical crisis” due to COVID-19 vaccinations - Sept 2022
• Hair loss is increased by stress: example 4X increase by COVID (hint: Vitamin D) – Sept 2022
• COVID in hospital fought by Vitamin D (25,000 IU daily for 4 days, then 25K weekly) - RCT – July 2022
• We had an inexpensive life-saving solution both before and during the pandemic (Vitamin D) - Malone May 2022
• Australia’s COVID Response resulted in 31 X more life years lost than were saved - Sept 2022
• Congress members demand FDA Investigate COVID-19 Vaccine Injuries – Sept 2022
• Early puberty during pandemic (perhaps just low vitamin D) - Sept 2022
• Vitamin D energizes the innate and adaptive immune systems to fight lung inflammation – Sept 2022
• COVID increased seniors risk of Alzheimer's by 1.7X in the next year- Sept 2022
• Pfizer vaccination trial – 1 in 800 actually had a serious adverse event – Sept 2022
• Model discovered: More UV, less COVID (many excellent charts) – Sept 2022
• COVID kids were more likely to have a poor VDR (4.3 X), than low Vitamin D (2.6 X) – Sept 2022
• Worse COVID during 3Q pregnancy if 2.5 ng lower Vitamin D – meta-analysis Sept 2022
• COVID fought by the antioxidants: Vitamin D, Zinc, Vitamin C, and Selenium – Review Sept 2022
• Vitamin D Supplementation and COVID-19 Outcomes: Mounting Evidence and Fewer Doubts - Aug 2022
• Many viral infections can be fought by Vitamin D (Astronaut’s in this case)– Aug 2022
• COVID worse if lower Vitamin C, but not Vitamin D in this study – Aug 2022 Why C but NOT D?
• Vitamin D improves Sinovac vaccine (fast innate response) - July 2022
• COVID survival in Europe in 2020 best predicted by population-level Vitamin D (of 13 variables) – July 2022
• Vitamin D can provide HEALTH immunity to fight the Corona virus this fall - Aug 2022
• Super-immune do not get COVID symptoms (perhaps Vitamin D) - Aug 2022
• COVID children helped by Vitamin D, trial terminated: unethical to not give Vitamin D to all: – RCT July 2022
• Current Compherensive Approach to COVID-19 (293 pages) - July 2022
• Some countries give treatment kits containing vitamin D if test positive for COVID - July 2022
• Elderly who had been in COVID ICU were 4X more likely to die if low vitamin D – Nov 2022
• Pandemic of the Boosted: UK Data Reveal Problem With COVID Vaccinations - July 2022
• Pandemic Vitamin D levels dropped by 3.3 ng (perhaps less D, more health problems) – May 2022
• Long-COVID is now the biggest COVID concern - many studies
• Severe COVID 2.6 X less likely if supplement with Vitamin D – 26th meta-analysis - July 2022
• Calcifediol is in the title of 7 virus pages as of June 2022
• Some COVID hospitalizations are due to poor Vitamin D genes (Binding Protein in this commentary) – June 2022
• COVID, Cancer, etc. are Vitamin D low-hanging-fruit – Editorial June 2022
• COVID deaths are often of fully vaccinated in fully vaccinated countries – June 2022
• Both Omicron and Monkeypox show evidence of mutation by the human immune system – June 2022
• Treat COVID early with high-dose Vitamin D (20th as of June 2022)
• Vitamin D might mitigate endemic COVID - June 2022
• Vitamin D also provides COVID Neuroprotection – April 2022
• 89% are vaccinated, but Omicron BA.5 is surging (Portugal) June 2022
• COVID hospital deaths reduced 2X by 8 days of UVB – pilot RCT May 2022
• Surviving COVID with vitamins and minerals is not a myth – June 2022
  • Vitamin D is the only one which: 1) Can be done at home, 2) Needs only a single dose
• 400,000 IU of vitamin D 3 days after COVID symptoms reduced 14 day mortality by 3X – Annweiler RCT May 2022
• Patients hospitalized with COVID not helped by 500,000 IU of Vitamin D – RCT – May 2022
  • Suspect that they did not get the Vitamin D until 1 week after getting symptoms
  • both groups had adequate vitamin D levels upon entering hospital
• COVID-19 Is Treatable and Preventable With Vitamin D: Dr. Malone - May 24, 2022
• Less COVID if more vitamin D from food (Spain) – May 2022
• You Are Going to Get COVID Again … and Again … and Again once every 3 years
  • Unless you take Vitamin D
• Omicron BA.2.12.1 - US dominate form,100,000 cases daily - May 24, 2022
• Problems after childhood vaccinations - many studies - perhaps fewer problems if more Vitamin D
• Loading dose of Vitamin D for patients hospitalized with COVID (140,000 IU) – RCT completed 2021
• COVID Ventilation 2X less likely if 200,000 IU of Vitamin D when enter hospital – May 2022
• COVID in seniors 5X less likely to be severe if vegetarian (small study) – April 2022
• Inhaling Nitric Oxide 4 times a day (which increases Vitamin D) fights COVID - May 2022
• Forecast of 100 million more US COVID infections in fall and winter - May 2022
• Vitamin D, Immune function, and SARS-CoV2 – May 2022
• COVID death 5.2X more likely if Vitamin D deficient – May 2022
• Severe COVID while pregnant - none had taken any vitamin D – Oct 2021
• Risk factors for severe COVID in children are all related to low vitamin D (same as adults) - April 2022
• Innate immune suppression by SARS-CoV-2 mRNA vaccinations - April 2022
  • Dr. McCullough is one of the authors, in-depth look at VARS 2021 data
• COVID death 6.9X less likely if high Magnesium to Calcium ratio – April 2022
  • 13 Magnesium and COVID studies in VitaminDWiki
• 21 fewer days in hospital with ARDS (COVID) if 10,000 IU of Vitamin D daily after enter hospital – RCT April, 2022
  • Speculation: "No hospitalization if had gotten high dose vitamin D at COVID symptom onset"
• 4X less likely to get COVID following 4,000 IU daily for a month – RCT April 2022
• COVID and CVD deadly pandemics share a risk factor: low vitamin D - April 2022
• 29 X more likely to die of COVID if less than 20 ng of Vitamin D - March 2022
• 2.9 X less risk of COVID ICU if seniors had supplemented with Vitamin D (any amount) – April 2022
  • Data from Spring of 2020. Wonder why the 2 year delay
• Micronutrients such as vitamin D should improve vaccine effectiveness (and decrease side effects) – April 2022
• High altitudes reduce the COVID-19 infection (not a surprise) – April 2022
• Obesity, Hypovitaminosis D, and COVID-19 – April 2022
• COVID while pregnant: 2.6 X more likely to be Vitamin D deficient (need to supplement) - March 2022
• Pfizer vaccine produced 30 percent more antibodies if more vitamin D – July 2022
• COVID-XE variant can probably be fought by strong immune systems (Vitamin D, etc.) - April 2022
• COVID Long-Haul at 49 weeks: overactive immune system, type O blood - March 2022
• CDC and UK data reveal the COVID vaccines do not prevent cases, transmission, severe illness or deaths - April 3, 2022
• Children have less severe COVID, but just as much long-haul as adults - April 2022
• COVID-XE variant can probably be fought by strong immune systems (Vitamin D, etc.) - April 2022
• COVID breakthru 2X more likely if pregnant (should take Vitamin D) - April 2022
• COVID, like influenza, may be able to mutate to avoid vaccines for decades - March 2022
• Increase in COVID Omicron deaths among vaccinated (CA this time) - March 2022
• Risk of COVID not reduced by 3,200 IU of vitamin D during 6 months (no surprise) – RCT March 2022
• COVID length of stay: the best predictor was Vitamin D (of 70 parameters) – March 2022
• Review of Early Treatments of COVID-19 (within a few days of symptoms)
• Omicron-1 survives on surfaces 3X longer than original - March 18, 2022
• Compare symptoms of Omicron, Flu and Colds Vitamin D fights all of them
• Immune system both activates and uses vitamin D (in brain, fight COVID, etc.) - March 2022
• COVID length of stay: The best predictor was Vitamin D (of 70 parameters) – March 2022
• COVID: most places are dropping restrictions, some are surging, and a few are both - March 15, 2022
• Giving Vitamin D often reduced COVID Mortality– Review of 11 studies – March 2022
• 18 million excess global deaths in past 2 years: COVID plus collateral damage - Lancet March 2022
  • decreased Vitamin D due to lock-up is one of the possible causes
• Vitamin D of 30-40 ng fights COVID, Dr. Grimes on Liverpool Study - March 2022
• Vitamin D separately helps X or COVID, should help X with COVID (example: diabetes) – March 2022
  • Recall: 26 health problems associated with increased COVID risk, ALL are assoicated with low vitamin D
• COVID can be fought by healthy immune systems (vitamins, etc.) - Feb 2022
  • Note elsewhere: Vitamin D improved immune system so much that half did not even test positive 24th meta-analysis
• Vitamin D helps both the innate and adaptive immune systems fight COVID-19 – Jan 2022
• Only a single supplement taken before infection decreased COVID severity (vitamin D) – Feb 2022
• COVID children with multisystem inflammatory syndrome have less than 10 ng of vitamin D – March 2022
• Vitamin D supplementation reduced risk of COVID-19 ICU by 2.8 X – review of 10 reviews Feb 2022
• COVID vaccination makes 6X more antibodies in those having good levels of both vitamin D and Iron – June 2021
• VitaminDWiki interview and transcript - Jan 2022 143 minute - includes a section on early treatments for COVID
• 14 X less likely to have severe COVID if previously had more than 40 ng level of Vitamin D – Feb 2022
• How vitamins A, B, C, D, E, F (Omega), K fight COVID - Feb 2022
• Estrogen supplements may cut COVID-19 deaths by half (no surprise - more E, more Vitamin D) - Feb 2022
• Group achieving 30 ng (vs 26 ng) were 2X less likely to get COVID symptoms - RCT Jan 2022
• Vitamin D helps both the innate and adaptive immune systems fight COVID-19 – Jan 2022
• COVID test positive is about half as likely if have Vitamin D – 24th meta-analysis - Jan 2022
• FLCCC COVID guidelines now include vitamin D loading doses - Jan 2022
• Vitamin D and its’ role in Parkinson’s disease patients with COVID - Jan 2022
• COVID death rate was 3X lower in those with Multiple Sclerosis (85 pcnt were taking Vitamin D) - Jan 2022
• Vitamin D fights COVID (54 studies of 1,400,000 people) – 23rd meta-analysis - Dec 2021
• Vitamin D benefits ignored at a time they are most needed - Grant Jan 9, 2022
• Increase in non-COVID deaths (ages 18-64) in Indiana, India, etc. - Jan 5, 2022
• Vitamin D and COVID-19: a narrative review - Holick - Jan 4, 2022
• Two times less likely to test positive for COVID if vitamin D level more than 55ng, etc. – Dec 31, 2021
• Vitamin D and COVID - Davies, Benskin (Dark Horse video with transcript) - Dec 27, 2021
• Ivermectin taken before COVID decreased death rate by 68 percent (3,000 with Ivermectin vs 3,000 without) - Dec 24, 2021
• The Vitamin D Receptor is associated with many health problems perhaps SARS-COV-2 as well
• Dr. McCullough on COVID-19: vaccine problems, home treatment – video, transcript – Dec 13, 2021
• Far fewer vaccination antibodies against Omicron - Dec 14, 2021
• Did HIV help Omicron evolve - Dec 10, 2021
• COVID-19 death increased 2X if low Vitamin D (less than 10 to less than 30 ng) – 21st meta-analysis Dec 2021
• Most COVID patients had sticky blood platelets (Omega-3 helps) - Dec 2021
• 16,000 Physicians and Scientists Agree Kids Shouldn’t Get COVID Vaccine - Dec 15, 2021
• Florida A.G. recommends Vitamin D, Zinc, Quercetin, etc. to reduce risk of COVID - Dec 12, 2021
• Vitamin D and a Dr. in Israel - Campbell video and transcript - Dec 11, 2021
• Epstein-Barr Virus probably causes Long-COVID, CFS, and MS - many studies
• Pfizer knew of 290 kinds of COVID vaccine problems
• Vaccinated have HIGHER infection rates than unvaxxed (UK age 30-70) - Dec 9, 2021
• Rapid Vitamin D Delivery May Result in Better COVID Outcomes - Dec 9, 2021
• 11,321 Breakthru COVID cases in Massachusetts last week (fully vaccinated) - Dec 7, 2021
• COVID vaccines produce blood antibodies, not the needed mucosal antibodies - Dec 7, 2021
  • also has several Vitamin D & COVID videos
• Coronaviruses evolve faster with vaccinations, expect more beyond Omicron - Nov 30, 2021
• Omega-3 decreases heart disease and COVID: Harris and Patrick, video and transcript - Dec 2021
• COVID is also associated with low Vitamin K - many studies
• Compulsory COVID Interventions do not work (400 studies - GreenMed Info) Dec 1, 2021
• Vitamin D loading doses quickly and safely raise levels – meta-analysis Dec 2021
• Real Anthony Fauci - book synopsis by Masterjohn Dec 3, 2021
• Large dose of calcifediol or vitamin D up to 15 days before COVID hospitalization reduced death rates (1.5X, 1.3X) – Dec 2021
• COVID-19 infection risk 2X higher in vaccinated than previously infected (28,000 in Netherlands) – preprint Nov 24, 2021
• Higher COVID death rates in more obese counties - Dec 2021
• COVID Virus kept mutating for 154 days in an immunocompromised person – Dec 2020
• COVID-19 risk reduction by Vitamin D, etc. - Grassroots Health Nov 29, 2021
• Vitamin D appears to drop while fighting COVID but recover later – Nov 2021
• How obesity reduces the ability of vitamin D to fight health problems such as COVID - Nov 2021
• Vaccinated were 28 percent of cases, 23 percent of deaths (waning)- CDC Sept 2021
• 11 percent fewer COVID-19 deaths if lockdowns had allowed sunshine – Nov 2021
• Long-Haul COVID is somewhat less of a problem if vaccinated – Nov 2021
• Elderly vaccinated for COVID were 2X more likely to die of ischemic stroke (2930 vs 1180 deaths)– Nov 2021
• Younger are much less likely to die of COVID than elderly (posters) - Nov 2021
• 3.3 X more likely to die if infected with SARS-Cov-2 plus a second pathogen – meta-analysis May 2021
• Pfizer trial vaccinated 22,000: 1 COVID death prevented, but 4 died of heart attacks - Nov 2021
• Problems with vaccine use during a pandemic - Dr. Bossche 2021 - 2023
• 3,900 deaths within 2 weeks of 2nd vaccination in Sweden - Nov 18, 2021
• Discussion of COVID and 50 ng of Vitamin D (video and transcript)– Dr. Campbell Nov 17, 2021
• Vaccine definition by the CDC seems to now include Vitamin D - Sept 2021
• US is buying 5 billion dollars of Pfizer COVID pills (10 million dollars of Vitamin D might do as well) - Nov 2021
• Vaccination immunity is waning - Fauci - Nov 14, 2021
• Low Vitamin D etc. more than 3 months after COVID hospitalization – Sept 2021
• Bill Gates admits COVID-19 vaccines don't stop viral transmission - Nov 5, 2021
• COVID, influenza, hepatitis B, measles, etc. vaccine responses vary with Vitamin D and its receptor
• 2X more male teens died than normal in England this summer (perhaps vaccination) - Oct 2021
• Vaccine passports expire in 6 months in Israel, but not (yet) in the US - Oct 2021
• COVID probably fought by Vitamin D, might need 50 ng - Dr. Patrick Nov 8, 2021
• COVID-19 risk reduced by vitamin D supplementation – umbrella review of 7 meta-analysis – Oct 2021
• Perhaps 3X more likely to catch COVID-19 in a group (church) in Nov 2021 than Nov 2020
• Vaccination effectiveness dropped from 83 percent to ZERO after 9 months (Sweden, preprint) – Oct 2021
• COVID natural Immunity is most likely better than vaccination immunity- literature review by Masterjohn - Oct 2021
• COVID winter is coming again in Northern US, Canada, Europe, Russia - Nov 2021
• French recommended 200,000 IU of Vitamin D to stop COVID-19 - Jan 2021
• COVID-19 severity associated with 3 vitamin D genes – Oct 2021
• Vitamin D was the only supplement that fought COVID-19 (out of 6) – Oct 2021
• Colin Powell died of COVID-19 (he had 4 risk factors for low vitamin D) – Oct 18, 2021
• https://vdmeta.com/
  
• COVID-19 treated by Vitamin D (example: ICU reduced by 5X) – 20th meta-analysis Oct 13, 2021
• COVID-19 and Vitamin D (42 studies, consensus) – Oct 2021
• Vitamin D was a top COVID-19 treatment at 4 hospital groups - May 2021
  • ~ 83,000 patients
• COVID-19 and Vitamin D - Wikipedia Oct 10, 2021
• COVID-19 risk reduction by early treatment: 5X Vitamin D – Oct 8, 2021
• Dr. McCullough on COVID-19: vaccine problems, home treatment – video, slides, transcript – Oct and Dec 2021
• COVID-19 symptoms and comorbidities associated with the type of Vitamin D Receptor – Oct 2021
• COVID-19 and Vitamin D – expert consensus and guidelines (Annweiler, behind paywall) – Oct 2021
• Pfizer vaccine half as effective as Moderna after 6 months (fading or Delta) - Mayo preprint Aug 2021
• Severe COVID-19 2.5 X more likely if low vitamin D (23 studies) – 19th meta-analysis Oct 2021
• COVID-19 cases vs. vaccination (counties and countries) - Sept 2021
• 7 Symptoms predictive of COVID-19 (from 1,000,000 in UK) – Oct 2021
• Emergency treatments if get COVID-19 symptoms - Oct 2021

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Intervention

Intervention Trial Summary Table

Details on #5 = COVIT-TRIAL Dec 27
Note: >70% of the RCT using Vitamin D to fight COVID-19 are using at least 100,000 IU during the first week

 

 

Trial Results 40 studies in both Virus and Intervention

This list is automatically updated

 

Virus meta-analyses and Systematic Reviews

   Short URL for this section = is.gd/vdwmeta

Reviews

• Vitamin D supplementation reduced risk of COVID-19 ICU by 2.8 X – review of 10 reviews Feb 2022
• COVID-19 and Vitamin D (42 studies, consensus) – Oct 2021

 

Observe - Less likely to become infected

short URL to this section = https://is.gd/COVID_less

• 
• 14 X less likely to have severe COVID if previously had more than 40 ng level of Vitamin D – Feb 2022
• COVID-19 patients had low levels of Zinc, Vitamin A, Vitamin D, and Vitamin C – Sept 2021

Observe - Reduced Severity/Death

MORTALITY AND Virus (automatically updated):

• Vitamin D of 30-40 ng fights COVID, Dr. Grimes on Liverpool Study - March 2022
• Higher vitamin D, less severe COVID and deaths in hospital (in Iran this time) – Sept 2021

 

Vitamin D Dosing Recommendations for COVID-19

• COVID predicted to be a pandemic that could be stopped by high dose vitamin D - Feb 2020
• FLCCC COVID guidelines now include vitamin D loading doses - Jan 2022
• Vitamin D and COVID, review of evidence, loading dose if less than 50 ng - Masterjohn Sept 2021

Short URL for this section = https://is.gd/covitamind  https://is.gd/virusvitd

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