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COVID-19 increased chance of death within 6 months by 1.6X, even if not hospitalized – April 2021

High-dimensional characterization of post-acute sequalae of COVID-19

Nature (2021) https://doi.org/10.1038/s41586-021-03553-9
Ziyad Al-Aly, Yan Xie & Benjamin Bowe


Based on 73,000 Veterans Adminstration patients who got COVID-19 but who were not hospitalized
Ignored deaths during the first 30 days
Study was reported on by New York Times April 22, 2021

The founder of VitaminDWiki believes that:

  1. Vitamin D given to those with COVID-19 symptoms would have substantially decreased the later deaths
  2. A vaccination might have also increased the death rate - perhaps by a simmilar amount

MORTALITY AND Virus (automatically updated):

VitaminDWiki items with "LONG-HAUL" in the title

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 Download the PDF from VitaminDWiki

The acute clinical manifestations of COVID-19 are well characterized1,2; however, its post-acute sequalae have not been comprehensively described. Here, we use the national healthcare databases of the US Department of Veterans Affairs to systematically and comprehensively identify 6-month incident sequalae including diagnoses, medication use, and laboratory abnormalities in 30-day survivors of COVID-19. We show that beyond the first 30 days of illness, people with COVID-19 exhibit higher risk of death and health resource utilization. Our high dimensional approach identifies incident sequalae in the respiratory system and several others including

  • nervous system and neurocognitive disorders,
  • mental health disorders,
  • metabolic disorders,
  • cardiovascular disorders,
  • gastrointestinal disorders,
  • malaise, fatigue,
  • musculoskeletal pain, and
  • anemia.

We show increased incident use of several therapeutics including pain medications (opioids and non-opioids), antidepressants, anxiolytics, antihypertensives, and oral hypoglycemics and evidence of laboratory abnormalities in multiple organ systems. Analysis of an array of pre-specified outcomes reveals a risk gradient that increased across severity of the acute COVID-19 infection (non-hospitalized, hospitalized, admitted to intensive care). The findings show that beyond the acute illness, substantial burden of health loss — spanning pulmonary and several extrapulmonary organ systems — is experienced by COVID-19 survivors. The results provide a roadmap to inform health system planning and development of multidisciplinary care strategies to reduce chronic health loss among COVID-19 survivors.

Created by admin. Last Modification: Friday April 23, 2021 01:06:26 GMT-0000 by admin. (Version 6)

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15486 VA death_compressed.pdf PDF 2021 admin 23 Apr, 2021 00:45 9.00 Mb 123
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