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Bones not helped much by vitamin D (low dose or short term) National Osteoporosis Foundation – Feb 2016

The National Osteoporosis Foundation's position statement on peak bone mass development and lifestyle factors: a systematic review and implementation recommendations.

Osteoporos Int. 2016 Feb 8. [Epub ahead of print]
Weaver CM1, Gordon CM2,3, Janz KF4, Kalkwarf HJ5, Lappe JM6, Lewis R7, O'Karma M8, Wallace TC9,10,11, Zemel BS12,13.

Lifestyle choices influence 20-40 % of adult peak bone mass. Therefore, optimization of lifestyle factors known to influence peak bone mass and strength is an important strategy aimed at reducing risk of osteoporosis or low bone mass later in life. The National Osteoporosis Foundation has issued this scientific statement to provide evidence-based guidance and a national implementation strategy for the purpose of helping individuals achieve maximal peak bone mass early in life. In this scientific statement, we (1) report the results of an evidence-based review of the literature since 2000 on factors that influence achieving the full genetic potential for skeletal mass; (2) recommend lifestyle choices that promote maximal bone health throughout the lifespan; (3) outline a research agenda to address current gaps; and (4) identify implementation strategies. We conducted a systematic review of the role of individual nutrients, food patterns, special issues, contraceptives, and physical activity on bone mass and strength development in youth. An evidence grading system was applied to describe the strength of available evidence on these individual modifiable lifestyle factors that may (or may not) influence the development of peak bone mass (Table 1). A summary of the grades for each of these factors is given below. We describe the underpinning biology of these relationships as well as other factors for which a systematic review approach was not possible. Articles published since 2000, all of which followed the report by Heaney et al. [1] published in that year, were considered for this scientific statement. This current review is a systematic update of the previous review conducted by the National Osteoporosis Foundation [1]. Lifestyle Factor Grade Macronutrients  Fat D  Protein C Micronutrients  Calcium A  Vitamin D B  Micronutrients other than calcium and vitamin D D Food Patterns  Dairy B  Fiber C  Fruits and vegetables C  Detriment of cola and caffeinated beverages C Infant Nutrition  Duration of breastfeeding D  Breastfeeding versus formula feeding D  Enriched formula feeding D Adolescent Special Issues  Detriment of oral contraceptives D  Detriment of DMPA injections B  Detriment of alcohol D  Detriment of smoking C Physical Activity and Exercise  Effect on bone mass and density A  Effect on bone structural outcomes B Considering the evidence-based literature review, we recommend lifestyle choices that promote maximal bone health from childhood through young to late adolescence and outline a research agenda to address current gaps in knowledge. The best evidence (grade A) is available for positive effects of calcium intake and physical activity, especially during the late childhood and peripubertal years-a critical period for bone accretion. Good evidence is also available for a role of vitamin D and dairy consumption and a detriment of DMPA injections. However, more rigorous trial data on many other lifestyle choices are needed and this need is outlined in our research agenda. Implementation strategies for lifestyle modifications to promote development of peak bone mass and strength within one's genetic potential require a multisectored (i.e., family, schools, healthcare systems) approach.


 Download the 106 page PDF from VitaminDWiki
Typically they considered tfials using only 200 or 400 IU of vitamin D
Sometimes trials used Vitamin D2
Typically trials lasted less than 12 weeks
Continued to focus on Calcium - which actually CAUSES many health problems
Continued to focus on Bone DENSITY rather than bone STRENGTH
Did not consider Magnesium other than one trial using Magnesium Oxide (which has poor bioavailability)
Did not mention that excessive Vitamin A reduces bone strength

See also VitaminDWiki

Pages listed in BOTH the categories Bone and Magnesium

Pages listed in BOTH the categories Bone and Vitamin K2

Overview Osteoporosis and vitamin D contains the following summary

  • FACT: Bones need Calcium (this has been known for a very long time)
  • FACT: Vitamin D improves Calcium bioavailability (3X ?)
  • FACT: Should not take > 750 mg of Calcium if taking lots of vitamin D (Calcium becomes too bio-available)
  • FACT: Adding vitamin D via Sun, UV, or supplements increased vitamin D in the blood
  • FACT: Vitamin D supplements are very low cost
  • FACT: Many trials, studies. reviews, and meta-analysis agree: adding vitamin D reduces osteoporosis
  • FACT: Toxic level of vitamin D is about 4X higher than the amount needed to reduce osteoporosis
  • FACT: Co-factors help build bones.
  • FACT: Vitamin D Receptor can restrict Vitamin D from getting to many tissues, such as bones
  • It appears that to TREAT Osteoporosis:
  •        Calcium OR vitamin D is ok
  •        Calcium + vitamin D is good
  •        Calcium + vitamin D + other co-factors is great
  •        Low-cost Vitamin D Receptor activators sometimes may be helpful
  • CONCLUSION: To PREVENT many diseases, including Osteoporosis, as well as TREAT Osteoporosis
  • Category Osteoporosis has 187 items
  • Category Bone Health has 265 items

Note: Osteoporosis causes bones to become fragile and prone to fracture
  Osteoarthritis is a disease where damage occurs to the joints at the end of the bones

Osteoporosis category includes the following

Pages in BOTH the categories Osteoporosis and Meta-analysis

Falls and Fractures category contains the following summary

The Meta-analysis of Falls/Fractures

Attached files

ID Name Comment Uploaded Size Downloads
6397 NOF Feb 2016.pdf PDF 2016 admin 10 Feb, 2016 12:53 1.84 Mb 718
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