Possible site-specific effect of an intervention combining nutrition and lifestyle counselling with consumption of fortified dairy products on bone mass: the Postmenopausal Health Study II.
Bone Miner Metab. 2011 Apr 1.
Moschonis G, Kanellakis S, Papaioannou N, Schaafsma A, Manios Y.
Department of Nutrition and Dietetics, Harokopio University of Athens, 70, El.Venizelou Ave, Kallithea, 176 71, Athens, Greece, gmoschi at hua.gr.
The aim of the present study was to examine whether a holistic approach combining nutrition and lifestyle counselling with the consumption of milk and yoghurt enriched with calcium, vitamin D(3) and phylloquinone (vitamin K(1)) or menaquinone (vitamin K(2)) would have any additional benefit on bone mineral density (BMD) indices measured at various skeletal sites using two different techniques, dual energy X-ray absorptiometry and quantitative ultrasonography (QUS). A sample of 115 postmenopausal women were randomized to three intervention groups, receiving daily via fortified milk and yoghurt and for 12 months,
- 800 mg calcium, 10 ?g vitamin D(3) (CaD group, n = 26);
- 800 mg calcium, 10 ?g vitamin D(3) and 100 ?g vitamin K(1) (CaDK1 group, n = 26);
- 800 mg calcium, 10 ?g vitamin D(3) and 100 ?g vitamin K(2) (CaDK2 group, n = 24); and a
- control group (CO group, n = 39) following their usual diet.
All three intervention groups attended biweekly nutrition and lifestyle counselling sessions.
Total BMD significantly increased in all three intervention groups and these changes were significantly higher compared to the CO (P < 0.001). Furthermore, the significant increases observed for L2-L4 BMD in the CaDK1 and CaDK2 groups were found to be significantly higher compared to the decrease observed in the CO (P = 0.001). No significant differences were observed for QUS parameters.
The combined approach used in the current study led to favourable changes for all three intervention groups in total body BMD, while an additional benefit was observed for L2-L4 BMD in CaDK1 and CaDK2 groups.
No significant differences were observed among groups in any of the QUS parameters.
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Interesting: most studies have found that 800+ IU of vitamin D is needed to increase bone density unless have magnesium
- 400 IU of Vitamin D Magnesium and Calcium helped Twin bones – Feb 2011
- Calcium in food increased much more than Magnesium in recent decades April 2010
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- Overview2 of Magnesium
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- Overview - Bone Fractures
- Osteoporosis prevented and treated by vitamin D and K- July 2007
- Overview Seniors lack Vitamin D
- National Osteoporosis Foundation on Vitamin D - more than 30 ng - 2010 800 to 1000 IU daily for elderly
- Lowest cost osteoporosis treatment was vitamin D and Calcium – Oct 2010
- Low cost co-factors for vitamin D More than Calcium is needed for healthy bones
- Vitamin D and Fracture Prevention – June 2010
- Vitamin D and calcium for the prevention of fractures
- Osteoporosis reduced by 800 or more IU of vitamin D - July 2010
- Would there be fewer stress and bone fractures with vitamin D?
- 4000 IU Vitamin D intervention helped elderly bones – March 2010
- 890 IU of vitamin D and 1200 mg Calcium improved bone density – July 2010
- Calcium and just 900 IU of vitamin D can improve Bone Density – July 2010
- Calcium citrate and more than 800 IU of vitamin D to treat Osteoporosis – Mar 2011
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