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Autism treated by Vitamin D (monthly injection of 150,000 IU) – June 2017

Clinical improvement following vitamin D3 supplementation in Autism Spectrum Disorder.

Nutr Neurosci. 2017 Jun;20(5):284-290. doi: 10.1080/1028415X.2015.1123847. Epub 2016 Jan 18.
Feng J1, Shan L1, Du L1, Wang B1, Li H1, Wang W1, Wang T1, Dong H1, Yue X1, Xu Z2, Staal WG3, Jia F1,4,5.
ABCD
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Social
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Self Help
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Not as much benefit if > 3 year
- Perhaps need higher dose if more weight?

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Autism category in VitaminDWiki starts with

Autism category has 154 items

 - see also Overview Autism and vitamin D,  Autoimmune ,   Cognitive,    ADHD
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Autism associated with low Vitamin D

Autism treated by Vitamin D

Autism reduced by vitamins before and during pregnancy

Autism and Vitamin D Receptor (not enough Vit D gets to the cells)
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Dr. Cannell on Autism and Vitamin D in VitaminDWiki

Autism and Omega-3
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This study used 3 monthly injections of 150,000 IU (no vary with child weight nor Vitamin D Level)

 Download the PDF from Sci-Hub via VitaminDWiki

OBJECTIVE:
High prevalence of vitamin D deficiency was previously reported in children with Autism Spectrum Disorder (ASD), but little is known about the efficacy of vitamin D3 treatment in ASD, although data from pilot studies seem promising. We hypothesized that serum vitamin D levels are reduced in ASD and correlate with the severity of disease. Also, we hypothesized that vitamin D3 treatment may be beneficial for a considerable portion of children with ASD.

METHODS:
In total, 215 children with ASD and 285 healthy control children were recruited in our study. Thirty seven of 215 ASD children received vitamin D3 treatment. The Autism Behaviour Checklist (ABC) and the Childhood Autism Rating Scale (CARS) were used to assess autism symptoms. High-performance liquid chromatography was used to assess the serum 25-hydroxyvitamin D [25(OH) D] level. Evaluations of ABC, CARS, and serum 25(OH) D levels were performed before and after 3 months of treatment.

RESULTS:
Serum levels of 25(OH) D were significantly lower in ASD children than typically developing children. Levels of serum 25(OH) D were negatively correlated with ABC total scores and language subscale scores. After vitamin D3 supplementation, symptom scores were significantly reduced on the CARS and ABC. In addition, the data also suggest that treatment effects were more pronounced in younger children with ASD.

CONCLUSION:
Vitamin D deficiency might contribute to the aetiology of ASD. Supplementation of vitamin D3, which is a safe and cost-effective form of treatment, may significantly improve the outcome of some children with ASD, especially younger children (identifier ChiCTR-CCC-13004498).

CLINICAL TRIAL REGISTRATION:
The trial 'Association of Polymorphisms of Vitamin D Metabolism-Related Genes With Autism and the Treatment of Autism with Vitamin D' has been registered at www.chictr.org/cn/proj/show.aspx? proj=6135 (identifier ChiCTR-CCC-13004498).

PMID: 26783092 DOI: 10.1080/1028415X.2015.1123847


Created by admin. Last Modification: Sunday December 22, 2019 03:48:29 GMT-0000 by admin. (Version 7)

Attached files

ID Name Comment Uploaded Size Downloads
9455 Autism 3 year.jpg admin 06 Mar, 2018 15.63 Kb 1547
9454 Autism self-help.jpg admin 06 Mar, 2018 14.47 Kb 1463
9453 Autism social.jpg admin 06 Mar, 2018 15.24 Kb 1497
9452 Autism ABC.jpg admin 06 Mar, 2018 15.57 Kb 1698
9451 Autism injection.pdf admin 06 Mar, 2018 870.28 Kb 1255