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Angina dramatically reduced by injections of vitamin D twice a month (300,000 IU) – Jan 2015

Vitamin D replacement therapy in patients with cardiac syndrome X

Perfusion January 2015 vol. 30 no. 1 60-63
A Andishmand, Z Ansari, MH Soltani, H Mirshamsi mirshamsih at yahoo.com, S Raafat
Cardiovascular Research Center, Afshar Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Hamide Mirshamsi Cardiovascular Department Afshar Hospital, Jomhoori Blvd Yazd, 8917945556 Iran.

Aims: The aim of present study was to assess whether vitamin D, with proven beneficial effects on the cardiovascular system, has any effect on angina and exercise-induced ischemia in patients with cardiac syndrome X and low serum vitamin D.

Methods: Patients with cardiac syndrome X and low serum vitamin D3 were studied before and after treatment with an intramuscular injection of vitamin D3 (300,000 units, every other week for 2 months). We determined the angina episode (per day) and several indices of exercise capacity.

Results: At the end of the treatment course (75±6 day),

  • a significant increase of serum vitamin D3 occurred and was within the normal range (45±8 ng/ml) and
  • the frequency of angina improved significantly (p=0.003).
  • Exercise duration and maximal work capacity increased significantly (p<0.001).
  • Maximal ST-segment depression (mm) decreased significantly (p=0.001).
  • The calculated Duck treadmill score improved significantly (p=0.001).

Conclusions: Our findings show that vitamin D replacement therapy in patients with cardiac syndrome X and vitamin D deficiency dramatically improves symptoms and signs of ischemia.
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It appears that the main benefit of injection is that the doctor get more income and does not have to worry about compliance
secondary reason for using injection - poor digestion
300,000 IU averaged over 14 days could be as well accomplished by other means
Example: 50,000 IU of vitamin D every 2nd day

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VitaminDWiki Cardiovascular pages with "Cardiac syndrome X" in title (3 as of Nov 2022)

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Items found: 3

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Attached files

ID Name Comment Uploaded Size Downloads
7891 cardiac syndrome X.pdf admin 05 Apr, 2017 333.98 Kb 735
7276 Angina reduced.pdf admin 02 Nov, 2016 91.09 Kb 1036