J Am Coll Nutr. 2018 Apr 13:1-5. doi: 10.1080/07315724.2018.1446194. Epub ahead of print
Botros RM1, AbdElsalam Besibes MM1, Bahaaeldin AM1, Abo Elyazed S1,2.
1 Department of Internal Medicine and Endocrinology , Faculty of Medicine, Ain Shams University , Cairo , Egypt.
2 Department of Internal Medicine and Endocrinology , Faculty of Medicine, Ain Shams University , Cairo , Egypt.
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Vitamin D deficiency is rarely considered or treated in critically ill patients. Deficiency of 25-hydroxy vitamin D [25(OH)D] prior to hospital admission might be a significant predictor of short- and long-term all cause patient mortality in a critically ill patient. The aim of this work is to investigate the prevalence of vitamin D deficiency in hospitalized patients and its relation to the length of stay and outcome of hospitalization.
Prospective cohort study performed on 80 patients admitted with acute deterioration of their chronic illness. Four groups of diseases were included, namely, chronic liver diseases (CLD), chronic obstructive pulmonary diseases (COPD), cerebrovascular stroke (CVS), and heart failure (HF). The patients were followed up until their discharge, or transfer, or death. Patients were sampled for their vitamin D level on admission and were divided according to their vitamin D status into sufficient, insufficient, and deficient. Statistical methods and analysis of the present study were conducted using the SPSS V17 program.
Vitamin D level had a significant inverse correlation with length of hospital stay (r = -0.648) (p < 0.001). In vitamin D-deficient and -insufficient groups, there was a significant difference between survivors and nonsurvivors as regards vitamin D levels and an inverse correlation between vitamin D level and outcome of hospital admission.
CONCLUSIONS: Vitamin D deficiency and insufficiency are significantly associated with a longer hospital stay and a poor outcome of hospital admission in comparison to control.
PMID: 29652593 DOI: 10.1080/07315724.2018.1446194
A separate study in May 2018 found no benefit of Vitamin D - 20ng instead of 30 ng as the breakpoint
Correlation of admission serum 25-hydroxyvitamin D levels and clinical outcomes in critically ill medical patients