Loading...
 
Translate Register Log In Login with facebookLogin and Register

A poor Vitamin D Receptor is associated with many cancers (oral cancer in this case) – Jan 2019

Role of vitamin D and vitamin D receptor (VDR) in oral cancer.

Biomed Pharmacother. 2019 Jan;109:391-401. doi: 10.1016/j.biopha.2018.10.102. Epub 2018 Nov 3.
Fathi N1, Ahmadian E2, Shahi S2, Roshangar L3, Khan H4, Kouhsoltani M5, Maleki Dizaj S6, Sharifi S7.
Vitamin D Receptor VDW10617

After activated Vitamin D gets past the 3 levels of VDR it can fight Cancer in 6 ways

Calcitriol Fights Cancer VDW10617

VitaminDWiki

Many cancers have evolved to protect themselves by deactivating the VDR
A deactivated VDR limits the amount of Vitamin D (Calcitriol) actually getting to the tissues
There appear to be 10+ simple/low-cost ways to increase the VDR activation
The risk of 40 diseases at least double with poor Vitamin D Receptor as of July 2019



Items in both categories Vitamin D Receptor and Cancer - Breast:

Items in both categories Vitamin D Receptor and Cancer - Colon:

Items in both categories Vitamin D Receptor and Cancer

Items in both categories Vitamin D Receptor and Cancer - other:

Items in both categories Vitamin D Receptor and Cancer - Skin:

Items in both categories Vitamin D Receptor and Cancer - Prostate:

Items in both categories Vitamin D Receptor and Cancer - Lung:

 Download the PDF from VitaminDWiki

Oral cancer is known as one of the most common cancers, with a poor prognosis, related to delayed clinical diagnosis, either due to the lack of particular biomarkers related to the disease or costly therapeutic alternatives. Vitamin D executes its functions by interacting with the vitamin D receptor (VDR), both in healthy and diseased individuals, including oral cancer. This review discusses the role of vitamin D and VDR on tumorigenesis, emphasizing on oral cancer. Furthermore, regulation of VDR expression, mechanisms of anticancer effects of calcitriol, oral cancer chemoresistance and its relation with VDR and polymorphisms of VDR gene will be discussed. The manuscript is prepared mainly using the information collected from PubMed and MEDLINE.
Clipped from PDF
"It have been reported that there are significant associations in VDR polymorphisms within cancers of

  • bladder (Fok1),
  • colorectal (Fok1, Bsm1),
  • ovary (Fok1, Apa1),
  • skin (Fok1, Bsm1, A-1210),
  • renal cell carcinoma (Taq1, Apa1),
  • prostate (Bsm1, Fok1, Taq1, poly (A)) and
  • breast (Taq1, Fok1, Bsm1, Apa1, poly (A)"
Created by admin. Last Modification: Friday July 12, 2019 02:17:11 GMT-0000 by admin. (Version 17)

Attached files

ID Name Comment Uploaded Size Downloads
11666 VDR Oral Cancer.pdf admin 26 Mar, 2019 13:03 2.00 Mb 31
See any problem with this page? Report it (FINALLY WORKS)