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34 clinical practice Vitamin D guidelines, huge diversity (PDF is behind a paywall) – Sept 2021


Vitamin D recommendations in clinical guidelines:
A systematic review, quality evaluation and analysis of potential predictors - Sept 2021

Int J Clin Pract. 2021 Sep 6;e14805. doi: 10.1111/ijcp.14805
D Fraile Navarro 1 2 3, A López-García-Franco 1 2, E Niño de Guzmán 4, M Rabassa 4, R Zamanillo Campos 5 6 7, H Pardo-Hernandez 8 9, I Ricci-Cabello 5 7 9, C Canelo-Aybar 10 11, J F Meneses-Echavez 12 13, J J Yepes-Nuñez 14 15, J Kuindersma 16, I Gich-Saladich 4 9 17, P Alonso-Coello 4 9

Background: Vitamin D has been widely promoted for bone health through supplementation and fortification of the general adult population. However, there is growing evidence that does not support these strategies. Our aim is to review the quality and recommendations on vitamin D nutritional and clinical practice guidelines and explore predictive factors for their direction and strength.

Methods: We searched three databases and two guideline repositories from 2010 onwards. We performed a descriptive analysis, a quality appraisal using AGREE II scores (Appraisal of Guidelines Research and Evaluation) and a bivariate analysis evaluating the association between direction and strength of recommendations, AGREE II domains' scores and pre-specified characteristics.

Results: We included 34 guidelines,

  • 44.1% recommended,
  • 26.5% suggested, and
  • 29.4% did not recommend vitamin D supplementation.

Guidelines that scored higher for "editorial independence" and "overall quality score" were less likely to recommend or suggest vitamin D supplementation (median 68.8 vs. 35.4; p=0.001), and median 58.3 vs. 37.5; p=0.02). Guidance produced by government organizations and those that reported source of funding were associated with higher AGREE II scores. Unclear role of source of funding was associated with recommending or suggesting vitamin D supplementation (p=0.034). Editorial independence was an independent predictor for recommending or suggesting vitamin D supplementation (OR 1.09; CI95% 1.02 to 1.16; p=0.006).

Conclusions: Policymakers, clinicians and patients should be aware that lower quality guidelines, and those reporting conflicts of interest are more likely to promote vitamin D supplementation. Guideline organizations should improve the quality of their recommendations' development and the management of conflicts of interest. Users and editors should be aware of these findings when using and appraising guidelines.


Dose size needed by an individual varies a lot

  1. Amount needed varies with obesity
  2. Amount needed varies with age
    • Small bodies need small doses
    • Seniors need more - indoors a lot and poor UVB adsorption
  3. Amount needed varies with skin color
  4. Amount needed varies with genes
  5. Amount needed varies with heallth problem to be prevented
  6. Amount needed varies with heallth problem to be treated
  7. Amount needed increases if poor gut when not use a gut-friendly form

Dose size needed has increasing much faster than any consensus can ever be made

Vitamin D levels have been crashing since 1995 (Polish Children, Elite Military, etc)
Many reasons why vitamin D deficiency has become epidemic
Incidence of 22 health problems related to vitamin D have doubled in a decade


Lack of any consensus


30 most-recently changed items in VitaminDWiki Consensus Vitamin D

Id Page Hits Last modification Creator Categories
12880 34 clinical practice Vitamin D guidelines, huge diversity (PDF is behind a paywall) – Sept 2021 299
06 Sep, 2021 20:13
admin How much Vitamin D
Consensus
10402 Vitamin D restoration then monthly was the most popular dosing by trials – Nov 2018 2302
30 Aug, 2021 14:59
admin Loading dose for Vitamin D
Top news
Consensus
12755 Doctors have a lot to learn about Vitamin D (Polish doctors in this case) – July 2021 343
23 Jul, 2021 01:58
admin Overview for doctors
Consensus
12741 Minimum National Vitamin D recommendations range from 200 to 4,000 IU – July 2021 318
15 Jul, 2021 13:07
admin Consensus
2617 Why are doctors reluctant to accept vitamin D 18232
23 Jun, 2021 18:26
admin Overview for doctors
Consensus
10953 FDA allows specific Omega-3 health claims - July 2019 1906
05 Jun, 2021 01:43
admin Top news
Vitamin D and Omega-3
Consensus
6658 Consensus Vitamin D 18687
30 May, 2021 20:03
admin Category
Consensus
4530 30 to 50 ng of vitamin D is optimal – Central Europe consensus Sept 2013 15883
30 May, 2021 18:10
admin Overview for doctors
Top news
Vitamin D in Europe
Optimum
Consensus
9623 Vitamin D sufficiency 10 to 30 ng, optimal 40 to 80 ng (no consensus)– May 2018 2130
30 May, 2021 18:09
admin Deficiency of Vitamin D
Optimum
Consensus
2028 Is 50 ng of vitamin D too high, just right, or not enough 52018
22 Apr, 2021 01:50
admin Optimum
Too much D
Consensus
12150 Consensus: Upper Limit of daily Vitamin D intake is still 4,000 IU (if you do not reduce Calcium) – Aug 2020 761
05 Jan, 2021 22:50
admin Supplement
Vitamin D and Calcium
Consensus
12059 Controversies and consensus in Vitamin D – 3rd Conference Sept 2019 519
29 Dec, 2020 21:56
admin Overview for doctors
Consensus
Conference
11869 A call to action: Vitamin D for hip fracture (50,000 weekly for 8 weeks, then bi-weekly – Holick July 2020 789
11 Dec, 2020 23:48
admin Falls and Fractures
Consensus
9991 Global Vitamin D recommendations - summer 2018 6831
25 Oct, 2020 00:23
admin Top news
Consensus
10001 4,000 IU of Vitamin D is OK - 19 organizations agree - 2018 4972
25 Oct, 2020 00:20
admin Top news
Consensus
11820 Vitamin D Consensus 4,000 to 10,000 IU, upper limit 100 ng – Italy 2018 1197
23 Oct, 2020 22:04
admin Consensus
6946 2,000 IU vitamin D recommended for pediatric rheumatology – May 2015 6921
13 Sep, 2020 16:45
admin Bone - Health
Lupus
Rheumatoid Arthritis
Infant-Child
Consensus
10575 Vitamin D RDA of 600 IU is not enough - global RCT meta-analysis March 2019 2308
21 Aug, 2020 21:12
admin How, when to take Vit. D
Predict Vitamin D
Consensus
10805 Need 40 to 60 ng of Vitamin D – 48 scientists call for action – 2015 2360
05 Aug, 2020 12:41
admin Optimum
Consensus
7351 Vitamin D and Rickets consensus took 80 years – how long till consensuses on 30 other health problems – Feb 2016 4404
02 Aug, 2020 20:06
admin Rickets
Consensus
11870 Call to Action: Eliminate Vitamin D Deficiency during COVID-19 (7 reasons) – Manson July 23, 2020 933
28 Jul, 2020 19:54
admin Consensus
Virus
10920 Call to action – more Vitamin D for pregnancies, loading doses are OK – Holick Aug 2019 1698
28 Jul, 2020 15:08
admin Pregnancy
Consensus
1293 Vitamin D Recommendations around the world - IU and ng 77954
12 May, 2020 01:57
admin How much Vitamin D
Top news
Consensus
7692 Vitamin D voting by panel – agreed upon bone health and high risk of chronic diseases – July 2016 3442
17 Mar, 2020 21:55
admin Health
Consensus
9302 Vitamin D Consensus, Brazil – Many people need 30 – 60 ng – Nov 2017 3459
17 Mar, 2020 12:10
admin Top news
Consensus
10285 Multiple Sclerosis - Coimbra Protocol (high-dose Vitamin D) - by one of the 120 doctors of 20,000 patients - Dec 2018 7644
02 Mar, 2020 17:58
admin Multiple Sclerosis
Autoimmune
Consensus
7787 Vitamin D improves a child’s immune system – can now be claimed in Europe – Sept 2016 2315
02 Mar, 2020 15:17
admin Immunity
Infant-Child
Consensus
10203 Vitamin D consensus for Italian children, 30 ng needed, up to 4,000 IU if over age 10 – May 2018 1573
13 Nov, 2019 17:10
admin Youth
Infant-Child
Consensus
8551 50,000 IU of vitamin D every two weeks – Jordan conclusion - RCT July 2017 4612
20 Oct, 2019 13:32
admin How much Vitamin D
Intervention
Consensus
Intervention - non daily
9022 US admits math mistake was made in 2010 in estimating Vitamin D, but will not change recommendations – Nov 2017 7533
22 May, 2019 22:22
admin How much Vitamin D
Top news
Consensus

VitaminDWiki pages with RECOMMEND in title (119 as of Sept 2021)

This list is automatically updated

Items found: 118
Title Modified
Wide variation in vitamin D recommendations (in this case, pregnant in Australia) – Aug 2021 23 Aug, 2021
Minimum National Vitamin D recommendations range from 200 to 4,000 IU – July 2021 15 Jul, 2021
Annweiler recommendations for Vitamin D for COVID-19, etc. often start with 200,000 - June 2021 22 Jun, 2021
Consensus recommends at least 20 ng of Vitamin D for childhood cancer (not nearly enough) – June 2021 08 Jun, 2021
Recommends vitamin D after hip fracture ( but not enough and no-bone building co-factors) – May 2021 21 May, 2021
Expert panel recommends Vitamin D for COVID-19, but fails recommend how much – May 2021 17 May, 2021
Omega-3 recommended in Australia during pregnancy - April 2021 14 Apr, 2021
Pregnancy recommendations – huge differences in Vitamin D, Mg, iron, Iodine, DHA, etc – April 2021 13 Apr, 2021
Ireland - Vitamin D often less than 20 ng, recommends only 800 IU - April 2021 09 Apr, 2021
Vitamin D recommendations for COVID-19 – Spanish Geriatrics Society – March 2021 04 Mar, 2021
Vitamin D to prevent COVID- strange trial recommendations from the UK – Jan 2021 18 Jan, 2021
Vitamin D recommended to fight COVID-19 by 2 groups – Dec 7, 2020 11 Dec, 2020
Vitamin D and COVID-19: Video and PDF by Dr. Grant (includes recommendations)- Nov 25, 2020 26 Nov, 2020
Vitamin D should fight COVID-19 (but Irish Consortium recommends only 1,000 IU) – Nov 21, 2020 21 Nov, 2020
French National Academy recommended 100,000 IU of Vitamin D to elderly to fight COVID-19 - May 2020 08 Nov, 2020
COVID-19 was killing dark-skinned doctors, then they got a Vitamin D recommendation 28 Oct, 2020
1,200 IU of Vitamin D now recommended if you consume 3,000 calories daily (FDA) – 2018 06 Oct, 2020
WHO recommends zero vitamin D during pregnancy, rest of the world disagrees – 2018, 2020 16 Aug, 2020
Weekly oral Vitamin D recommended before surgery (Bariatric in this case) – RCT June 2019 19 Jul, 2020
Vitamin D recommended for COVID-19 – yet another study – July 17, 2020 18 Jul, 2020
Vitamin D Recommendations around the world - IU and ng 12 May, 2020
Vitamin D should prevent COVID-19 (recommended dose takes 3 months to raise levels) - April 2020 03 Apr, 2020
Synthetic EPA drug recommended to FDA for Cardio (Omega-3 is 8 X better) – Nov 2019 13 Jan, 2020
Omega-3 during pregnancy and breastfeeding is recommended – May 2019 23 May, 2019
Omega-3 – only 5 percent of US physicians have recommended amount – Dec 2017 13 Jan, 2019
A paltry 400 IU Vitamin D recommended during pregnancy - NICE UK Dec 2018 17 Dec, 2018
None of the Czech groups got the recommended Vitamin D from food – Oct 2018 07 Oct, 2018
Alaska recommends more vitamin D: Infancy 800 IU, Pregnancy 1400 IU (avoid rickets) Sept 2018 15 Sep, 2018
Global Vitamin D recommendations - summer 2018 30 Aug, 2018
Vitamin D has been recommended for Cystic Fibrosis – a small dose helps a little – Aug 2018 11 Aug, 2018
Recommended increasing vitamin D for space flight – NASA Sept 2013 24 Jul, 2018
US admits math mistake was made in 2010 in estimating Vitamin D, but will not change recommendations – Nov 2017 17 Jul, 2018
Less than half of health providers recommend 600 to 1000 IU of vitamin D (age 1-18) – May 2018 25 May, 2018
Children need vitamin D - good global overview, poor recommendations for Italian children - May 2018 16 May, 2018
Vitamin D recommendations by Italian Endocrinologists – 40 ng if pregnant, 30 ng if high risk – April 2018 27 Apr, 2018
Italian consensus of recommended Vitamin D, Omega-3, etc – Oct 2016 27 Apr, 2018
Omega-3 helps the heart, AHA class II recommendation, more than 1 gm may be needed – March 2018 26 Mar, 2018
Healthy pigs get at least 2 X more vitamin D than the govt recommends 01 Mar, 2018
Pregnancies helped by Vitamin D – recommendations and trials underway – review Dec 2017 02 Jan, 2018
IoM admits math mistake was made in 2009 in estimating Vitamin D, but will not change their recommendations – Nov 2017 22 Nov, 2017
Review of vitamin D recommendations around the world – April 2017 22 Nov, 2017
Turkey recommended 1200 IU Vitamin D during pregnancy, only 1 in 7 took more than 1,000 IU – Sept 2017 14 Sep, 2017
Canadian Paediatric Society – vitamin D recommendations unchanged since 2007 – Jan 2017 21 Aug, 2017
2010 recommendations for Vitamin D are Deficient – by 1997 panelists 08 Aug, 2017
Infant-Child Vitamin D recommendations from NZ (many are wrong) – Feb 2017 13 Jul, 2017
Endocrine Society recommend higher vitamin D levels – June 2011 14 Apr, 2017
Do not expect a doctor to recommend a pill which will eliminate his job (vitamin D) 27 Feb, 2017
Review of the Benefits of Vitamin D and Recommendations – Jan 2017 09 Jan, 2017
Osteoporosis helped by Vitamin D, still not willing to recommend exact dose size – Nov 2016 23 Nov, 2016
The CDC recommendations for Zika prevention – Aug 2016 04 Oct, 2016
Only 1 in 5 toddlers get recommended minimum vitamin D – Sept 2016 16 Sep, 2016
Calcitriol (active Vitamin D) recommended after kidney transplant – March 2014 28 Apr, 2016
Animals get a lot more vitamin D than minimum recommended for humans – 2016 31 Mar, 2016
Vitamin D recommendations barely help even bones – March 2016 23 Mar, 2016
Vitamin D recommendations should reduce Rickets (but not much else) - March 2016 23 Mar, 2016
Vitamin D Recommendations during Pregnancy, Lactation and Early Infancy – Nov 2011 14 Mar, 2016
Vitamin D deficiency and childhood obesity: interactions, implications, and recommendations (5,000 IU) – Feb 2016 05 Feb, 2016
Recommend 100 IU of vitamin D per kg of infant - Poland July 2011 04 Feb, 2016
World Health Organization considering new pregnancy Vitamin D recommendations - behind paywall Nov 2015 11 Nov, 2015
Chronic kidney with low vitamin D: 90 percent of pediatric nephrologists now recommend more D – Feb 2013 27 Oct, 2015
2,000 IU vitamin D recommended for pediatric rheumatology – May 2015 29 Sep, 2015
Pediatric rheumatologists – recommend 2,000 IU vitamin D supplementation – May 2015 29 Sep, 2015
Why Most Calcium Supplement Recommendations are DEAD WRONG - Sept 2013 30 Jun, 2015
Osteoporosis groups hide their vitamin D recommendations behind 40 dollar paywall – May 2015 03 May, 2015
Osteoporosis groups hide their synthetic vitamin D recommendations behind 40 dollar paywall – May 2015 03 May, 2015
Autism cured in a child with Vitamin D, Dr. Cannell comments and cofactor recommendations – March 2015 27 Mar, 2015
Dr. Oz recommends at least 50 ng of vitamin D 20 Mar, 2015
Cystic Fibrosis Foundation recommends vitamin D dose, patients are taking even more – March 2015 17 Mar, 2015
HIV children in UK – Vitamin D recommendations – Feb 2014 22 Jan, 2015
Polish conference recommended vitamin D levels from 30 to 60 ng – Oct 2012 30 Dec, 2014
Shape Magazine recommends a max of 1,000 IU of vitamin D (wrong) - Dec 2014 23 Dec, 2014
Recommended levels of vitamins and minerals - history RDA DRI 23 Dec, 2014
Child Bone health – (incorrect) recommendations by US Pediatric and Bone Health groups – Sept 2014 30 Sep, 2014
Vitamin D recommended for all animals (FEEDAP does not say how much) – Feb 2014 30 Sep, 2014
Child Bone health – recommendations by US Pediatric and Bone Health groups – Sept 2014 29 Sep, 2014
Institute of Medicine (which recommended low vitamin D) has many conflicts of interest – July 2014 15 Jul, 2014
There have been no studies of vitamin D testing resulting in less disease – so task force recommends that there be no testing June 2014 24 Jun, 2014
Cancer Council of Australia recommends 30 minutes of daily sunshine – June 2014 04 Jun, 2014
Tasmania Vitamin D official recommendation 20 up to 200 ng – March 2014 20 Mar, 2014
Governments recommend a small amount of vitamin D, people consume even less – March 2014 04 Mar, 2014
Dr. Oz again recommends at least 50 ng of vitamin D - Dec 2013 05 Jan, 2014
Task force for senior fall prevention finally recommends 800 IU of vitamin D – May 2012 16 Dec, 2013
5,000 IU recommended by Vitamin D Council - Dec 2013 16 Dec, 2013
Dr Oz recommends 50 ng vitamin D blood level 03 Dec, 2013
Review of Vitamin D recommendations and knowledge – Oct 2013 28 Nov, 2013
HIV – recommend 100,000 IU vitamin D monthly to get levels 30 ng – May 2013 18 Oct, 2013
Only about 10 percent of breastfed infants get even the minimum recommended vitamin D – April 2010 26 Jun, 2013
Japanese recommendations without RDA: Vitamin D about 200 IU, Vitamin K about 60 ug– May 2013 08 May, 2013
European Osteo group recommends 20-50 ng of vitamin D – Jan 2013 17 Jan, 2013
Most German skin cancer doctors recommend both sunscreen and vitamin D – Dec 2012 12 Dec, 2012
Nordic countries considering raising vitamin D to US recommended levels – Dec 2012 02 Dec, 2012
French Society of Paediatics Vitamin D recommendations – Jan 2012 15 Nov, 2012
Chief UK Medical Officer recommends only 280 IU for children - Jan 2011 12 Nov, 2012
Variety of vitamin D loading dose recommendations in the UK - 2011 28 Oct, 2012
Nordic mothers vitamin D deficient even though meet recommendations – April 2010 04 Sep, 2012
Review of Parkinson's disease and vitamin D recommends use of active form – Aug 2012 29 Aug, 2012
Hip fractures in India - editorial with recommendation - Sept 2010 06 Jul, 2012
Vitamin D 2nd most recommended way to prevent next hip fracture – Nov 2010 23 Jun, 2012
Poland Vitamin D recommendations - 2009 23 Jun, 2012
OBGYN College in UK still recommends only 400 IU during pregnancy – Jan 2012 18 Jun, 2012
Review of vitamin D recommendations – April 2012 01 May, 2012
Piglets get more vitamin D than recommended by the govt, for piglets or humans – March 2012 27 Mar, 2012
When will it become a crime to fail to recommend or provide vitamin D 17 Mar, 2012
Calves do well with 1930 IU of vitamin D - 6X more that feed recommendations - May 2010 07 Feb, 2012
Vitamin D level recommendations - Bosomworth Jan 2011 06 Jan, 2012
Grade A recommendations for vitamin D - May 2009 07 Nov, 2011
NLM Vitamin D recommendations and interactions – Jan 2011 21 Oct, 2011
25 experts recommend vitamin D level of min 30 ng – Nov 2009 24 Sep, 2011
100 IU increases 1 ng vitamin D – recommend 3000 IU – Book 2011 27 Aug, 2011
Recommend 2500-4000 IU per day to reduce all-cause mortality by 18%– Grant Netherlands April 2010 13 Jul, 2011
Why the IOM Recommendations for Vitamin D Are Deficient – Mar 2011 26 Feb, 2011
Only 18 percent of Swedes got recommended amount of vitamin D – Feb 2011 09 Feb, 2011
Experts Recommend 10000 IU Upper Limit Vitamin D – 2007 17 Oct, 2010
Osteoporosis Foundation recommends 30 ng – May 2010 29 Sep, 2010
Recommend 400 IU to prevent rickets – Mar 2010 25 Sep, 2010
Vitamin D books recommended by VitaminDResearch today 02 Jul, 2010
Recommendations to elderly- avoid UV but take vitamin D – May 2010 27 Jun, 2010
36% of pediatricians recommend adding vitamin D – Nov 2009 30 May, 2010

Created by admin. Last Modification: Monday September 6, 2021 20:13:16 GMT-0000 by admin. (Version 7)
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