- Personalized Vitamin D dosing ranged from 2,000 IU to 140,000 weekly for Breast Cancer:
- A range of 70 to 1
- Treating healthy people typically requires a range of Vitamin D of only 4 to 1
- The women getting Breast Cancer treatment were clearly not uniformly unhealthy
- The study failed to note improvement in outcomes vs women not getting Vitamin D
- Shorter treatment durations, less chemo used, less recurrence
- Course of Vitamin D Levels in Newly Diagnosed Non-Metastatic Breast Cancer Patients over One Year with Quarterly Controls and Substitution
- VitaminDWiki -
22 studies in both categories Breast Cancer and After Cancer Diagnosis - VitaminDWiki - Vitamin D: not one size, type, form, route for all - Jan 2022
- VitaminDWiki - Huge variation in response to vitamin D supplementation – personal vitamin D response index – Dec 2016
- VitaminDWiki - Personalized treatment of Vitamin D
- VitaminDWiki – Cancer - After diagnosis category contains:
Course of Vitamin D Levels in Newly Diagnosed Non-Metastatic Breast Cancer Patients over One Year with Quarterly Controls and Substitution
Nutrients. 2024 Mar 15;16(6):854. doi: 10.3390/nu16060854.
Cosima Zemlin 1 2, Laura Altmayer 1, Marina Lang 1, Julia Theresa Schleicher 1, Caroline Stuhlert 1, Carolin Wörmann 1, Laura-Sophie Scherer 1, Ida Clara Thul 1, Lisanne Sophie Spenner 1, Jana Alisa Simon 1, Alina Wind 1, Elisabeth Kaiser 3 4, Regine Weber 3 4, Sybelle Goedicke-Fritz 3 4, Gudrun Wagenpfeil 5, Michael Zemlin 3, Erich-Franz Solomayer 1, Jörg Reichrath 6, Carolin Müller 1 2 7Apparently they adjusted dosing quarterly (goal of 30 to 100 ng): used 2,000 to 140,000 IU weekly
Background: Vitamin D levels in patients remain inadequately understood, with research yielding inconsistent findings. Breast cancer patients, particularly due to oncological therapies, face an increased risk of osteopenia, which can be exacerbated by a vitamin D deficiency.Methods: The prospective observational "BEGYN-1" study assessed serum 25(OH D levels at baseline and quarterly thereafter. Clinical, pathological, nutritional, vitamin supplementation, and lifestyle data were recorded.
Results: Before treatment, 68.5% of patients were vitamin D deficient (<30 ng/mL), with 4.6% experiencing severe deficiency (<10 ng/mL). The median baseline 25(OH)D levels were 24 ng/mL (range: 4.8 to 64.7 ng/mL). Throughout the study, the median vitamin D levels increased to 48 ng/mL (range: 22.0 to 76.7 ng/mL). Before diagnosis, 16.7% received vitamin D substitution, and 97.8% received vitamin D substitution throughout the year with a median weekly dose of 20,000 IU. It took at least three quarterly assessments for 95% of patients to reach the normal range. A multiple GEE analysis identified associations between 25(OH)D levels and supplementation, season, age, VLDL, magnesium levels, and endocrine therapy.
Conclusions: Physicians should monitor 25(OH)D levels before, during, and after oncological therapy to prevent vitamin D deficiency and to adjust substitution individually. While variables such as seasons, age, VLDL, magnesium, diet, and oncological interventions affect 25(OH)D levels, supplementation has the greatest impact.
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VitaminDWiki -
22 studies in both categories Breast Cancer and After Cancer Diagnosis This list is automatically updated
- Lots of Vitamin D needed weekly during Breast Cancer Treatment (mean 20,000 IU up to 140,000 IU) – March 2024
- Breast Cancer survival: 44% with just 10,000 IU of vitamin D per week, 33% with placebo – RCT Dec 2023
- Breast Cancer survivors with high vitamin D were 3.3 X less likely to have metastases – May 2023
- Breast Cancers with the lowest Vitamin D levels were more likely to metastasize – Sept 2022
- Breast cancer chemo made more women vitamin D insufficient, even 6 months later– 2019
- Breast Cancer chemo reduces Bone Mineral Density, injecting Vitamin D increases it – Sept 2019
- Chemotherapy for Breast Cancer lowers Vitamin D levels – Oct 2018
- Vitamin D prevents breast cancer, reduces BC mortality, and reduces BC chemotherapy problems – Sept 2018
- Breast cancer recurred twice as often if have less than 20 ng of vitamin D – Dec 2018
- Following breast cancer 100K IU Vitamin D doses twice a month helped a lot – RCT July 2016
- Breast Cancer chemotherapy 2.7 X more likely to be successful if not vitamin D deficient – Dec 2017
- Breast Cancer trial using 50,000 IU Vitamin D weekly cancelled (no funding)
- Increased Breast Cancer metastasis if low vitamin D or poor VDR – Feb 2016
- Breast Cancer Chemotherapy dropped Vitamin D levels by 6 nanograms – Nov 2015
- Breast cancer chemotherapy benefits from highest vitamin D levels – June 2014
- 85 percent less risk of death from Breast Cancer when vitamin D levels higher than 30 ng – May 2012
- Vitamin D after breast cancer diagnosis - May 2012
- Breast Cancer Chemotherapy initially decreases vitamin D levels – May 2012
- Aromatase inhibitor chemotherapy after breast cancer not associated with vitamin D levels – Dec 2011
- Cancer patients 64% less likely to die if have high level of vitamin D – Dec 2011
- Vitamin D and breast cancer radiation
- Vitamin D3 sensitizes breast cancer to radiation treatment - increasing cancer cell death – May 2010
VitaminDWiki - Vitamin D: not one size, type, form, route for all - Jan 2022
VitaminDWiki - Huge variation in response to vitamin D supplementation – personal vitamin D response index – Dec 2016
VitaminDWiki - Personalized treatment of Vitamin D
VitaminDWiki – Cancer - After diagnosis category contains:
- Most cancers reduce vitamin D levels
- Most cancer treatments (chemo, radiation) further lower Vitamin D
- Higher levels of vitamin D minimize many side-effects of cancer therapy
- High levels of vitamin D augment many chemotherapies
- High levels of vitamin D augment cancer immunotherapies
- High levels of vitamin D can kill some cancer cells 1,720 items 12/2023
- Some cancers deactivate the vitamin D receptor
Example VitaminDWiki Studies
- Cancer and Vitamin D - many studies
- Easiest way to treat cancer – take Vitamin D – Nov 2022
- Even after a Cancer diagnosis Vitamin D improves survival – meta-analysis Aug 2022
- Vitamin D is synergistic with many Cancer therapies (radiation in this case) – Aug 2021
- Vitamin D prevents and treats cancer in many ways – May 2021
- Cancer patients need more vitamin D, even those who are supplementing – observational study June 2021
- Metastatic Cancer probably reduced by vitamin D - many studies
- Colorectal Cancer treatment aided by omega-3 plus weekly Vitamin D – RCT Sept 2019
- Radiation therapy, used to treat some cancers, causes less damage if use Vitamin D (or Melatonin) – Aug 2022
- Vitamin D is synergistic with many Cancer therapies (radiation in this case) – Aug 2021
- Vitamin D prevents and treats cancer in many ways – May 2021
- Palliative care is helped by Vitamin D - many studies
- 4X less of one chemo needed after vitamin D receptor activation - June 2020
Breast Cancer
- Breast Cancer survivors with high vitamin D were 3.3 X less likely to have metastases – May 2023
- Breast Cancer survival: 44% with just 10,000 IU of vitamin D per week, 33% with placebo – RCT Dec 2023
- Breast cancer recurred twice as often if have less than 20 ng of vitamin D – Dec 2018
- Breast Cancer chemotherapy 2.7 X more likely to be successful if not vitamin D deficient – Dec 2017
Lots of Vitamin D needed weekly during Breast Cancer Treatment (mean 20,000 IU up to 140,000 IU) – March 2024(Cached) Printer Friendly Follow this page for updates297 visitors, last modified 29 Mar, 2024, This page is in the following categories (# of items in each category)Attached files
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